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The map label for this gene is yjgI [C]

Identifier: 121639708

GI number: 121639708

Start: 4209568

End: 4210332

Strand: Direct

Name: yjgI [C]

Synonym: BCG_3853

Alternate gene names: 121639708

Gene position: 4209568-4210332 (Clockwise)

Preceding gene: 121639707

Following gene: 121639709

Centisome position: 96.23

GC content: 64.71

Gene sequence:

>765_bases
ATGGTTCTTGATGCCGTAGGAAACCCCCAGACGGTGCTGCTGCTCGGTGGCACCTCCGAGATCGGGCTCGCCATCTGCGA
GCGCTACCTGCACAATTCGGCGGCCCGCATCGTGCTGGCCTGCCTGCCCGACGACCCACGGCGGGAGGACGCGGCCGCTG
CGATGAAGCAGGCCGGCGCGCGGTCGGTGGAGCTGATCGACTTTGACGCCCTGGATACCGACAGCCACCCGAAGATGATC
GAGGCGGCCTTCTCCGGCGGTGATGTGGACGTGGCTATCGTCGCGTTCGGCTTGCTCGGCGACGCCGAAGAGCTGTGGCA
GAACCAGCGCAAGGCGGTGCAGATCGCCGAAATCAACTACACCGCAGCGGTTTCGGTGGGCGTGCTGCTGGCTGAGAAGA
TGCGCGCTCAGGGCTTCGGTCAGATCATCGCGATGAGCTCGGCCGCCGGTGAGCGGGTGCGACGGGCGAACTTCGTCTAC
GGCTCCACCAAGGCCGGTCTGGACGGGTTTTACCTGGGGTTGTCAGAAGCGCTGCGCGAGTACGGTGTTCGTGTGCTGGT
GATCCGGCCCGGCCAGGTGCGTACCCGGATGAGCGCGCACCTCAAGGAAGCTCCATTGACCGTCGACAAGGAGTACGTCG
CCAACCTCGCGGTGACCGCGTCCGCAAAAGGTAAGGAATTGGTTTGGGCGCCAGCAGCGTTCCGCTACGTCATGATGGTG
TTGCGTCACATCCCGCGGAGCATCTTCCGCAAGCTGCCCATCTGA

Upstream 100 bases:

>100_bases
CATGTATCCGCGCGTCGACGAATGGATCTCCGTGCGCCGCAAGGTCGATCCGCTGCGCGTATTCGCCTCCGACATGGCCC
GACGCTTGGAGCTGCTGTAG

Downstream 100 bases:

>100_bases
GTATGCCGAGCAGACGCAAAAGCCCCCAATTCGGGCACGAAATGGGGGCTTTTACGTCTGCTCGCGCCCGGGAGGTGCTG
GTCGCTCTTGGCCAGCTGGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGARSVELIDFDALDTDSHPKMI
EAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVY
GSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMV
LRHIPRSIFRKLPI

Sequences:

>Translated_254_residues
MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGARSVELIDFDALDTDSHPKMI
EAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVY
GSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMV
LRHIPRSIFRKLPI
>Mature_254_residues
MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGARSVELIDFDALDTDSHPKMI
EAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINYTAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVY
GSTKAGLDGFYLGLSEALREYGVRVLVIRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMV
LRHIPRSIFRKLPI

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the reduction of at C-2 of decaprenylphosphoryl 2-ket

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPRE2_MYCTU (P66783)

Other databases:

- EMBL:   BX842584
- EMBL:   AE000516
- PIR:   C70697
- RefSeq:   NP_218308.1
- RefSeq:   NP_338450.1
- ProteinModelPortal:   P66783
- EnsemblBacteria:   EBMYCT00000000873
- EnsemblBacteria:   EBMYCT00000070331
- GeneID:   886124
- GeneID:   922605
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3899
- KEGG:   mtu:Rv3791
- TIGR:   MT3899
- TubercuList:   Rv3791
- GeneTree:   EBGT00050000015167
- HOGENOM:   HBG750976
- OMA:   GQVRTKM
- ProtClustDB:   PRK07904
- BioCyc:   MetaCyc:MONOMER-15262
- GO:   GO:0005488
- GO:   GO:0040007
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081

Pfam domain/function: PF00106 adh_short

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27469; Mature: 27469

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 160-160 BINDING 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGA
CEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
RSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINY
CEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEHHHHHHCCCHHHHHHHHHHEEEEEECCC
TAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSEALRE
HHHHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHH
YGVRVLVIRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMV
CCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEECHHHHHHHHHH
LRHIPRSIFRKLPI
HHHHHHHHHHHCCC
>Mature Secondary Structure
MVLDAVGNPQTVLLLGGTSEIGLAICERYLHNSAARIVLACLPDDPRREDAAAAMKQAGA
CEECCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
RSVELIDFDALDTDSHPKMIEAAFSGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAEINY
CEEEEEEECCCCCCCCCHHHHHHCCCCCEEEEHHHHHHCCCHHHHHHHHHHEEEEEECCC
TAAVSVGVLLAEKMRAQGFGQIIAMSSAAGERVRRANFVYGSTKAGLDGFYLGLSEALRE
HHHHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHH
YGVRVLVIRPGQVRTRMSAHLKEAPLTVDKEYVANLAVTASAKGKELVWAPAAFRYVMMV
CCCEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEECHHHHHHHHHH
LRHIPRSIFRKLPI
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036