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The map label for this gene is aftA

Identifier: 121639709

GI number: 121639709

Start: 4210335

End: 4212266

Strand: Direct

Name: aftA

Synonym: BCG_3854

Alternate gene names: 121639709

Gene position: 4210335-4212266 (Clockwise)

Preceding gene: 121639708

Following gene: 121639710

Centisome position: 96.25

GC content: 68.63

Gene sequence:

>1932_bases
ATGCCGAGCAGACGCAAAAGCCCCCAATTCGGGCACGAAATGGGGGCTTTTACGTCTGCTCGCGCCCGGGAGGTGCTGGT
CGCTCTTGGCCAGCTGGCAGCGGCGGTGGTAGTGGCCGTCGGTGTCGCGGTGGTGTCCCTGCTCGCCATTGCGCGGGTGG
AGTGGCCCGCCTTCCCGTCGTCCAACCAGCTGCATGCGCTGACCACCGTCGGCCAGGTCGGCTGCCTGGCCGGGCTGGTC
GGCATCGGCTGGTTGTGGCGGCACGGTCGATTCCGGCGACTGGCCCGGCTGGGCGGGCTGGTTTTGGTATCCGCGTTTAC
CGTCGTGACGCTGGGCATGCCGCTGGGCGCCACCAAGCTGTATCTGTTCGGCATCTCTGTCGACCAGCAGTTCCGCACCG
AATACCTCACCAGGCTCACCGACACCGCCGCCCTGCGCGACATGACCTACATCGGACTGCCACCGTTTTACCCACCGGGC
TGGTTCTGGATCGGCGGACGCGCGGCGGCGCTGACCGGGACGCCGGCCTGGGAGATGTTCAAGCCGTGGGCGATCACCTC
GATGGCCATTGCGGTGGCCGTCGCGCTGGTGCTGTGGTGGCGGATGATCCGCTTCGAATACGCCTTGCTGGTCACCGTCG
CCACAGCGGCGGTGATGCTGGCCTACAGCTCGCCGGAGCCCTACGCCGCGATGATCACGGTGTTGTTGCCGCCGATGCTC
GTACTGACCTGGTCGGGCCTGGGCGCGCGCGACCGTCAGGGCTGGGCCGCGGTGGTCGGTGCCGGCGTCTTCCTGGGCTT
CGCGGCCACCTGGTACACCCTGTTGGTCGCCTACGGCGCGTTCACGGTGGTGCTGATGGCGCTGCTGCTGGCCGGGTCGC
GGCTGCAATCCGGAATCAAGGCGGCGGTAGACCCGCTGTGCCGGCTTGCCGTCGTCGGCGCGATCGCGGCCGCCATCGGA
TCCACCACCTGGCTGCCCTACCTGCTGCGGGCGGCCCGCGACCCGGTCAGCGACACCGGCAGCGCCCAGCACTACCTACC
CGCAGACGGCGCCGCACTGACCTTCCCCATGCTGCAGTTCTCCCTGCTGGGCGCGATCTGTCTGCTGGGCACGCTGTGGC
TGGTGATGCGCGCGCGATCATCGGCGCCAGCCGGCGCCCTGGCCATCGGCGTGCTGGCCGTCTACCTGTGGTCCCTGCTG
TCGATGCTGGCCACATTGGCGCGCACCACACTGCTGTCGTTTCGCCTGCAGCCGACGCTGAGCGTGCTGCTGGTGGCGGC
CGGTGCGTTCGGCTTCGTCGAAGCGGTCCAAGCCCTTGGCAAACGGGGTCGCGGTGTCATTCCGATGGCCGCCGCCATCG
GGTTGGCCGGCGCGATCGCGTTCAGCCAGGACATCCCCGACGTGTTGCGGCCGGACCTGACCATCGCCTACACCGACACC
GACGGCTACGGCCAGCGCGGCGACCGGCGACCGCCCGGCTCCGAGAAGTACTACCCAGCCATCGATGCCGCCATCCGGCG
CGTCACCGGCAAGCGCCGCGATCGGACCGTCGTGTTGACCGCCGACTACAGCTTCCTGTCGTACTACCCCTACTGGGGCT
TTCAGGGGTTGACGCCGCACTACGCCAACCCGCTGGCACAGTTCGACAAGCGCGCCACACAGATCGACAGCTGGTCGGGA
CTCTCCACCGCCGACGAGTTCATCGCCGCGCTGGACAAGCTGCCCTGGCAGCCGCCGACCGTCTTCCTCATGCGCCACGG
CGCACATAACAGCTACACCCTGCGGCTGGCCCAGGACGTCTACCCCAACCAGCCCAATGTTCGCCGCTACACGGTGGACC
TACGGACCGCCCTCTTCGCCGACCCGCGTTTCGTCGTCGAGGACATTGGCCCGTTCGTGCTGGCCATCCGCAAGCCGCAG
GAGAGCGCGTGA

Upstream 100 bases:

>100_bases
AAGGTAAGGAATTGGTTTGGGCGCCAGCAGCGTTCCGCTACGTCATGATGGTGTTGCGTCACATCCCGCGGAGCATCTTC
CGCAAGCTGCCCATCTGAGT

Downstream 100 bases:

>100_bases
TGGCTACCGAAGCCGCCCCACCCCGTATCGCCGTCCGGCTACCATCTACCTCCGTGCGCGACGCGGGAGCAAACTACCGG
ATCGCCCGGTACGTCGCTGT

Product: putative transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAIARVEWPAFPSSNQLHALTTVGQVGCLAGLV
GIGWLWRHGRFRRLARLGGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRDMTYIGLPPFYPPG
WFWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALVLWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPML
VLTWSGLGARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSRLQSGIKAAVDPLCRLAVVGAIAAAIG
STTWLPYLLRAARDPVSDTGSAQHYLPADGAALTFPMLQFSLLGAICLLGTLWLVMRARSSAPAGALAIGVLAVYLWSLL
SMLATLARTTLLSFRLQPTLSVLLVAAGAFGFVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTIAYTDT
DGYGQRGDRRPPGSEKYYPAIDAAIRRVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKRATQIDSWSG
LSTADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVYPNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQ
ESA

Sequences:

>Translated_643_residues
MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAIARVEWPAFPSSNQLHALTTVGQVGCLAGLV
GIGWLWRHGRFRRLARLGGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRDMTYIGLPPFYPPG
WFWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALVLWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPML
VLTWSGLGARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSRLQSGIKAAVDPLCRLAVVGAIAAAIG
STTWLPYLLRAARDPVSDTGSAQHYLPADGAALTFPMLQFSLLGAICLLGTLWLVMRARSSAPAGALAIGVLAVYLWSLL
SMLATLARTTLLSFRLQPTLSVLLVAAGAFGFVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTIAYTDT
DGYGQRGDRRPPGSEKYYPAIDAAIRRVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKRATQIDSWSG
LSTADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVYPNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQ
ESA
>Mature_642_residues
PSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAIARVEWPAFPSSNQLHALTTVGQVGCLAGLVG
IGWLWRHGRFRRLARLGGLVLVSAFTVVTLGMPLGATKLYLFGISVDQQFRTEYLTRLTDTAALRDMTYIGLPPFYPPGW
FWIGGRAAALTGTPAWEMFKPWAITSMAIAVAVALVLWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPMLV
LTWSGLGARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSRLQSGIKAAVDPLCRLAVVGAIAAAIGS
TTWLPYLLRAARDPVSDTGSAQHYLPADGAALTFPMLQFSLLGAICLLGTLWLVMRARSSAPAGALAIGVLAVYLWSLLS
MLATLARTTLLSFRLQPTLSVLLVAAGAFGFVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTIAYTDTD
GYGQRGDRRPPGSEKYYPAIDAAIRRVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPHYANPLAQFDKRATQIDSWSGL
STADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDVYPNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQE
SA

Specific function: Involved in cell wall arabinan biosynthesis. Catalyzes the addition of the first key arabinofuranosyl residue from the sugar donor beta-D-arabinofuranosyl-1-monophosphoryldecaprenol to the galactan domain of the cell wall, thus 'priming' the galactan for

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 85 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AFTA_MYCBO (Q7TVN5)

Other databases:

- EMBL:   BX248347
- RefSeq:   NP_857458.1
- ProteinModelPortal:   Q7TVN5
- EnsemblBacteria:   EBMYCT00000017645
- GeneID:   1093628
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3821
- GeneTree:   EBGT00070000032387
- HOGENOM:   HBG429582
- OMA:   AEDVYPN
- ProtClustDB:   CLSK792726
- BioCyc:   MBOV233413:MB3821-MONOMER
- InterPro:   IPR020959
- InterPro:   IPR020963

Pfam domain/function: PF12249 AftA_C; PF12250 AftA_N

EC number: NA

Molecular weight: Translated: 69516; Mature: 69385

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x19fb735c)-; HASH(0x19a90de4)-; HASH(0x18ddea18)-; HASH(0x196cfe2c)-; HASH(0x196eae30)-; HASH(0x19ddf520)-; HASH(0x1990d308)-; HASH(0x19f3b7f0)-; HASH(0x19aadd9c)-; HASH(0x19a531ec)-; HASH(0x19e6afa8)-; HASH(0x18836848)-; HASH(0x19f24460)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAIARVEWPAFPS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SNQLHALTTVGQVGCLAGLVGIGWLWRHGRFRRLARLGGLVLVSAFTVVTLGMPLGATKL
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
YLFGISVDQQFRTEYLTRLTDTAALRDMTYIGLPPFYPPGWFWIGGRAAALTGTPAWEMF
EEEECCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCEEEECCEEEEECCCCCHHHC
KPWAITSMAIAVAVALVLWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VLTWSGLGARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSRLQSGIK
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAVDPLCRLAVVGAIAAAIGSTTWLPYLLRAARDPVSDTGSAQHYLPADGAALTFPMLQF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SLLGAICLLGTLWLVMRARSSAPAGALAIGVLAVYLWSLLSMLATLARTTLLSFRLQPTL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
SVLLVAAGAFGFVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTIAYTDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECC
DGYGQRGDRRPPGSEKYYPAIDAAIRRVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCCCCCH
YANPLAQFDKRATQIDSWSGLSTADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDV
HCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEHHC
YPNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQESA
CCCCCCCEEEEEEHHHHHHCCCCHHHHHCCCEEEEEECCCCCH
>Mature Secondary Structure 
PSRRKSPQFGHEMGAFTSARAREVLVALGQLAAAVVVAVGVAVVSLLAIARVEWPAFPS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SNQLHALTTVGQVGCLAGLVGIGWLWRHGRFRRLARLGGLVLVSAFTVVTLGMPLGATKL
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
YLFGISVDQQFRTEYLTRLTDTAALRDMTYIGLPPFYPPGWFWIGGRAAALTGTPAWEMF
EEEECCCCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCEEEECCEEEEECCCCCHHHC
KPWAITSMAIAVAVALVLWWRMIRFEYALLVTVATAAVMLAYSSPEPYAAMITVLLPPML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VLTWSGLGARDRQGWAAVVGAGVFLGFAATWYTLLVAYGAFTVVLMALLLAGSRLQSGIK
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAVDPLCRLAVVGAIAAAIGSTTWLPYLLRAARDPVSDTGSAQHYLPADGAALTFPMLQF
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SLLGAICLLGTLWLVMRARSSAPAGALAIGVLAVYLWSLLSMLATLARTTLLSFRLQPTL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
SVLLVAAGAFGFVEAVQALGKRGRGVIPMAAAIGLAGAIAFSQDIPDVLRPDLTIAYTDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECC
DGYGQRGDRRPPGSEKYYPAIDAAIRRVTGKRRDRTVVLTADYSFLSYYPYWGFQGLTPH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHCCCCCCCCCCCCH
YANPLAQFDKRATQIDSWSGLSTADEFIAALDKLPWQPPTVFLMRHGAHNSYTLRLAQDV
HCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEHHC
YPNQPNVRRYTVDLRTALFADPRFVVEDIGPFVLAIRKPQESA
CCCCCCCEEEEEEHHHHHHCCCCHHHHHCCCEEEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972