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The map label for this gene is rfbB [C]

Identifier: 121639701

GI number: 121639701

Start: 4202659

End: 4203639

Strand: Direct

Name: rfbB [C]

Synonym: BCG_3846

Alternate gene names: 121639701

Gene position: 4202659-4203639 (Clockwise)

Preceding gene: 121639700

Following gene: 121639702

Centisome position: 96.07

GC content: 58.82

Gene sequence:

>981_bases
ATGGAAATACTTGTCACCGGGGGCGCGGGCTTCCAGGGAAGCCATCTGACCGAGTCACTGCTGGCCAATGGGCATTGGGT
CACTGTCCTCGACAAGTCTTCGAGGAATGCGGTTCGTAACATGCAGGGATTTCGTTCGCATGACCGCGCCGCGTTCATAT
CCGGTTCGGTAACCGACGGCCAGACGATCGACCGCGCGGTGCGGGACCATCACGTCGTATTTCACCTGGCCGCGCATGTC
AACGTGGACCAGTCCTTGGGCGACCCGGAGAGCTTTCTCGAAACCAATGTCATGGGAACCTACCGCGTCCTGGAAGCCGT
CCGGCGCTACAGGAACCGCTTGATATACGTATCGACGTGCGAAGTCTACGGCGACGGACACAATCTCAAGGAAGGCGAAC
GACTTGACGAACACGCGGAGCTGAAGCCGAACAGTCCATATGGCGCTTCCAAGGCGGCGGCCGACCGCTTGTGCTACTCG
TACTTTCGCTCCTACGGACTCGACGTCACGATCGTCCGTCCGTTCAACATCTTCGGCGTCCGCCAAAAGGCTGGGCGATT
CGGCGCGCTGATTCCGCGGCTGGTCCGCCAGGGCATCAACGGTGAAGGCCTGACAATCTTCGGCGCAGGTAGCGCAACCC
GGGATTACCTGTATGTCAGTGACATCGTGGGCGCGTACAACCTGGTATTACGAACTCCAACCCTGCGTGGTCAGGCCATC
AATTTTGCCAGCGGGAAAGATACCCGGGTGAGGGACATCGTCGAGTATGTTGCGGACAAGTTCGGTGCCAGGATCGAGCA
CCGCGACGCTCGCCCCGGAGAGGTCCAGCGCTTTCCCGCTGACATTTCGCTTGCCAAAAGCATCGGGTTCCAGCCGCAAG
TCGAAATTTGGGACGGCATCGATCGCTATATCAATTGGGCCAAGGATCAGCCCCAATACCCATATGAGCAGGACGGGTTT
AGCGGTTCCAGCGTTCTCTAA

Upstream 100 bases:

>100_bases
GGGCCGCCGTTGATCTCAAGATCGGCTGGCAACGGCCGCGTACCAGCGGCAGCATGGATTAGGTTCACCGTTTGCCGATG
AGGCTCAGAGGGCGGGACGG

Downstream 100 bases:

>100_bases
TACACCCGTCGCCGCCATCGTCTGCCGGTAAAGTGGGCCGAAATGGCGCGGAACTACCAGCTGGAAGGATTACCTCCCAT
TCGATGGTGACCGTAGCACG

Product: putative dTDP-glucose 4,6-dehydratase rfbB

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEILVTGGAGFQGSHLTESLLANGHWVTVLDKSSRNAVRNMQGFRSHDRAAFISGSVTDGQTIDRAVRDHHVVFHLAAHV
NVDQSLGDPESFLETNVMGTYRVLEAVRRYRNRLIYVSTCEVYGDGHNLKEGERLDEHAELKPNSPYGASKAAADRLCYS
YFRSYGLDVTIVRPFNIFGVRQKAGRFGALIPRLVRQGINGEGLTIFGAGSATRDYLYVSDIVGAYNLVLRTPTLRGQAI
NFASGKDTRVRDIVEYVADKFGARIEHRDARPGEVQRFPADISLAKSIGFQPQVEIWDGIDRYINWAKDQPQYPYEQDGF
SGSSVL

Sequences:

>Translated_326_residues
MEILVTGGAGFQGSHLTESLLANGHWVTVLDKSSRNAVRNMQGFRSHDRAAFISGSVTDGQTIDRAVRDHHVVFHLAAHV
NVDQSLGDPESFLETNVMGTYRVLEAVRRYRNRLIYVSTCEVYGDGHNLKEGERLDEHAELKPNSPYGASKAAADRLCYS
YFRSYGLDVTIVRPFNIFGVRQKAGRFGALIPRLVRQGINGEGLTIFGAGSATRDYLYVSDIVGAYNLVLRTPTLRGQAI
NFASGKDTRVRDIVEYVADKFGARIEHRDARPGEVQRFPADISLAKSIGFQPQVEIWDGIDRYINWAKDQPQYPYEQDGF
SGSSVL
>Mature_326_residues
MEILVTGGAGFQGSHLTESLLANGHWVTVLDKSSRNAVRNMQGFRSHDRAAFISGSVTDGQTIDRAVRDHHVVFHLAAHV
NVDQSLGDPESFLETNVMGTYRVLEAVRRYRNRLIYVSTCEVYGDGHNLKEGERLDEHAELKPNSPYGASKAAADRLCYS
YFRSYGLDVTIVRPFNIFGVRQKAGRFGALIPRLVRQGINGEGLTIFGAGSATRDYLYVSDIVGAYNLVLRTPTLRGQAI
NFASGKDTRVRDIVEYVADKFGARIEHRDARPGEVQRFPADISLAKSIGFQPQVEIWDGIDRYINWAKDQPQYPYEQDGF
SGSSVL

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=315, Percent_Identity=30.1587301587302, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI7657641, Length=322, Percent_Identity=28.2608695652174, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI193211614, Length=246, Percent_Identity=28.4552845528455, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI8393516, Length=246, Percent_Identity=28.4552845528455, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI56237023, Length=350, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI56118217, Length=350, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI189083684, Length=350, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI48994969, Length=348, Percent_Identity=31.3218390804598, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=30.8605341246291, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=26.5861027190332, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788589, Length=261, Percent_Identity=28.735632183908, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788365, Length=254, Percent_Identity=24.0157480314961, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788366, Length=275, Percent_Identity=26.5454545454545, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=310, Percent_Identity=27.0967741935484, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17568069, Length=326, Percent_Identity=27.6073619631902, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=25.3602305475504, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=320, Percent_Identity=25.625, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=25, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=341, Percent_Identity=24.3401759530792, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=28.1150159744409, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI19923002, Length=347, Percent_Identity=25.9365994236311, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36306; Mature: 36306

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILVTGGAGFQGSHLTESLLANGHWVTVLDKSSRNAVRNMQGFRSHDRAAFISGSVTDG
CEEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCC
QTIDRAVRDHHVVFHLAAHVNVDQSLGDPESFLETNVMGTYRVLEAVRRYRNRLIYVSTC
HHHHHHHHHCEEEEEEEECCCCHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEE
EVYGDGHNLKEGERLDEHAELKPNSPYGASKAAADRLCYSYFRSYGLDVTIVRPFNIFGV
EEECCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEC
RQKAGRFGALIPRLVRQGINGEGLTIFGAGSATRDYLYVSDIVGAYNLVLRTPTLRGQAI
HHHHCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHEEECCCCCCCEE
NFASGKDTRVRDIVEYVADKFGARIEHRDARPGEVQRFPADISLAKSIGFQPQVEIWDGI
EECCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCHHHCCCCHHHHHHCCCCCCHHHHHCH
DRYINWAKDQPQYPYEQDGFSGSSVL
HHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEILVTGGAGFQGSHLTESLLANGHWVTVLDKSSRNAVRNMQGFRSHDRAAFISGSVTDG
CEEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCC
QTIDRAVRDHHVVFHLAAHVNVDQSLGDPESFLETNVMGTYRVLEAVRRYRNRLIYVSTC
HHHHHHHHHCEEEEEEEECCCCHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEEE
EVYGDGHNLKEGERLDEHAELKPNSPYGASKAAADRLCYSYFRSYGLDVTIVRPFNIFGV
EEECCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCEEEC
RQKAGRFGALIPRLVRQGINGEGLTIFGAGSATRDYLYVSDIVGAYNLVLRTPTLRGQAI
HHHHCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEHHHHHHHHHHEEECCCCCCCEE
NFASGKDTRVRDIVEYVADKFGARIEHRDARPGEVQRFPADISLAKSIGFQPQVEIWDGI
EECCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCHHHCCCCHHHHHHCCCCCCHHHHHCH
DRYINWAKDQPQYPYEQDGFSGSSVL
HHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]