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The map label for this gene is kasB [H]

Identifier: 121638128

GI number: 121638128

Start: 2498041

End: 2499357

Strand: Direct

Name: kasB [H]

Synonym: BCG_2263

Alternate gene names: 121638128

Gene position: 2498041-2499357 (Clockwise)

Preceding gene: 121638127

Following gene: 121638129

Centisome position: 57.1

GC content: 65.53

Gene sequence:

>1317_bases
GTGGGGGTCCCCCCGCTTGCGGGGGCGAGTCGGACCGATATGGAAGGAACGTTCGCAAGACCAATGACGGAGCTGGTTAC
CGGGAAAGCCTTTCCCTACGTAGTCGTCACCGGCATCGCCATGACGACCGCGCTCGCGACCGACGCGGAGACTACGTGGA
AGTTGTTGCTGGACCGCCAAAGCGGGATCCGTACGCTCGATGACCCATTCGTCGAGGAGTTCGACCTGCCAGTTCGCATC
GGCGGACATCTGCTTGAGGAATTCGACCACCAGCTGACGCGGATCGAACTGCGCCGGATGGGATACCTGCAGCGGATGTC
CACCGTGCTGAGCCGGCGCCTGTGGGAAAATGCCGGCTCACCCGAGGTGGACACCAATCGATTGATGGTGTCCATCGGCA
CCGGCCTGGGTTCGGCCGAGGAACTGGTCTTCAGTTACGACGATATGCGCGCTCGCGGAATGAAGGCGGTCTCGCCGCTG
ACCGTGCAGAAGTACATGCCCAACGGGGCCGCCGCGGCGGTCGGGTTGGAACGGCACGCCAAGGCCGGGGTGATGACGCC
GGTATCGGCGTGCGCATCCGGCGCCGAGGCCATCGCCCGTGCGTGGCAGCAGATTGTGCTGGGAGAGGCCGATGCCGCCA
TCTGCGGCGGCGTGGAGACCAGGATCGAAGCGGTGCCCATCGCCGGGTTCGCTCAGATGCGCATCGTGATGTCCACCAAC
AACGACGACCCCGCCGGTGCATGCCGCCCATTCGACAGGGACCGCGACGGCTTTGTGTTCGGCGAGGGCGGCGCCCTTCT
GTTGATCGAGACCGAGGAGCACGCCAAGGCACGTGGCGCCAACATCCTGGCCCGGATCATGGGCGCCAGCATCACCTCCG
ATGGCTTCCACATGGTGGCCCCGGACCCCAACGGGGAACGCGCCGGGCATGCGATTACGCGGGCGATTCAGCTGGCGGGC
CTCGCCCCCGGCGACATCGACCACGTCAATGCGCACGCCACCGGCACCCAGGTCGGCGACCTGGCCGAAGGCAGGGCCAT
CAACAACGCCTTGGGCGGCAACCGACCGGCGGTGTACGCCCCCAAGTCTGCCCTCGGCCACTCGGTGGGCGCGGTCGGCG
CGGTCGAATCGATCTTGACGGTGCTCGCGTTGCGCGATCAGGTGATCCCGCCGACACTGAATCTGGTAAACCTCGATCCC
GAGATCGATTTGGACGTGGTGGCGGGTGAACCGCGACCGGGCAATTACCGGTATGCGATCAATAACTCGTTCGGATTCGG
CGGCCACAACGTGGCAATCGCCTTCGGACGGTACTAA

Upstream 100 bases:

>100_bases
CCGCTACGCAGTCAACAACTCGTTCGGGTTCGGCGGCCACAATGTGGCGCTTGCCTTCGGGCGTTACTGAAGCACGACAT
CGCGGGTCGCGAGGCCCGAG

Downstream 100 bases:

>100_bases
ACCCCAGCGTTACGCGACAGGAGACCTGCGATGACAATCATGGCCCCCGAGGCGGTTGGCGAGTCGCTCGACCCCCGCGA
TCCGCTGTTGCGGCTGAGCA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: Beta-ketoacyl-ACP synthase 2; KAS 2 [H]

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MGVPPLAGASRTDMEGTFARPMTELVTGKAFPYVVVTGIAMTTALATDAETTWKLLLDRQSGIRTLDDPFVEEFDLPVRI
GGHLLEEFDHQLTRIELRRMGYLQRMSTVLSRRLWENAGSPEVDTNRLMVSIGTGLGSAEELVFSYDDMRARGMKAVSPL
TVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTN
NDDPAGACRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAG
LAPGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLVNLDP
EIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY

Sequences:

>Translated_438_residues
MGVPPLAGASRTDMEGTFARPMTELVTGKAFPYVVVTGIAMTTALATDAETTWKLLLDRQSGIRTLDDPFVEEFDLPVRI
GGHLLEEFDHQLTRIELRRMGYLQRMSTVLSRRLWENAGSPEVDTNRLMVSIGTGLGSAEELVFSYDDMRARGMKAVSPL
TVQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTN
NDDPAGACRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAG
LAPGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLVNLDP
EIDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY
>Mature_437_residues
GVPPLAGASRTDMEGTFARPMTELVTGKAFPYVVVTGIAMTTALATDAETTWKLLLDRQSGIRTLDDPFVEEFDLPVRIG
GHLLEEFDHQLTRIELRRMGYLQRMSTVLSRRLWENAGSPEVDTNRLMVSIGTGLGSAEELVFSYDDMRARGMKAVSPLT
VQKYMPNGAAAAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTNN
DDPAGACRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGL
APGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYAPKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLVNLDPE
IDLDVVAGEPRPGNYRYAINNSFGFGGHNVAIAFGRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=34.7721822541966, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=43.1506849315069, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI41872631, Length=254, Percent_Identity=31.8897637795276, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=36.7149758454106, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1788663, Length=405, Percent_Identity=33.0864197530864, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=31.5533980582524, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI71983535, Length=263, Percent_Identity=38.0228136882129, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI212642053, Length=381, Percent_Identity=27.8215223097113, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=25.8278145695364, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=32.8859060402685, Blast_Score=209, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24644341, Length=438, Percent_Identity=35.3881278538813, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI19920632, Length=392, Percent_Identity=26.2755102040816, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221330659, Length=392, Percent_Identity=26.2755102040816, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24581345, Length=433, Percent_Identity=23.7875288683603, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 46421; Mature: 46290

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVPPLAGASRTDMEGTFARPMTELVTGKAFPYVVVTGIAMTTALATDAETTWKLLLDRQ
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHEEECC
SGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRRMGYLQRMSTVLSRRLWENAGS
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEVDTNRLMVSIGTGLGSAEELVFSYDDMRARGMKAVSPLTVQKYMPNGAAAAVGLERHA
CCCCCCEEEEEECCCCCCHHHHEEEHHHHHHCCCCCCCCEEHHHHCCCCCHHHHHHHHHH
KAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTN
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEEEEEECCEEEEEEEEECC
NDDPAGACRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVA
CCCCCCCCCCCCCCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
PDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEC
PKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLVNLDPEIDLDVVAGEPRPGNYRYAI
CHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCCCEEEEE
NNSFGFGGHNVAIAFGRY
CCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
GVPPLAGASRTDMEGTFARPMTELVTGKAFPYVVVTGIAMTTALATDAETTWKLLLDRQ
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHEEECC
SGIRTLDDPFVEEFDLPVRIGGHLLEEFDHQLTRIELRRMGYLQRMSTVLSRRLWENAGS
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEVDTNRLMVSIGTGLGSAEELVFSYDDMRARGMKAVSPLTVQKYMPNGAAAAVGLERHA
CCCCCCEEEEEECCCCCCHHHHEEEHHHHHHCCCCCCCCEEHHHHCCCCCHHHHHHHHHH
KAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVETRIEAVPIAGFAQMRIVMSTN
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHEEEEEECCEEEEEEEEECC
NDDPAGACRPFDRDRDGFVFGEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVA
CCCCCCCCCCCCCCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
PDPNGERAGHAITRAIQLAGLAPGDIDHVNAHATGTQVGDLAEGRAINNALGGNRPAVYA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEC
PKSALGHSVGAVGAVESILTVLALRDQVIPPTLNLVNLDPEIDLDVVAGEPRPGNYRYAI
CHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEECCCCCCCEEEEE
NNSFGFGGHNVAIAFGRY
CCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]