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The map label for this gene is 121638090

Identifier: 121638090

GI number: 121638090

Start: 2452044

End: 2453582

Strand: Direct

Name: 121638090

Synonym: BCG_2225

Alternate gene names: NA

Gene position: 2452044-2453582 (Clockwise)

Preceding gene: 121638089

Following gene: 121638093

Centisome position: 56.05

GC content: 66.86

Gene sequence:

>1539_bases
ATGCCCGCATCACGACTGGTCAGACAAGTGTCTGCGCCACGGAACCTGTTCGGGCGGCTGGTTGCCCAGGGGGGCTTCTA
CACGGCCGGGCTGCAGTTGGGCAGCGGTGCGGTGGTACTGCCGGTCATCTGCGCACATCAGGGCCTCACCTGGGCGGCTG
GGCTGTTGTATCCGGCGTTCTGCATTGGCGCCATTCTGGGAAATTCGCTGTCGCCGCTGATTCTGCAGCGCGCCGGCCAG
CTCCGGCACCTGCTGATGGCGGCGATATCGGCGACGGCGGCGGCGCTGGTTGTGTGCAACGCTGCGGTCCCCTGGACTGG
CGTTGGCGTCGCCGCGGTTTTTTTGGCGACCACGGGGGCCGGTGGTGTCGTCACCGGAGTCTCCAGCGTCGCCTACACCG
ACATGATCTCCAGCATGTTGCCCGCGGTACGGCGGGGCGAGCTACTGCTCACCCAAGGTGCCGCGGGGTCGGTGCTGGCC
ACCGGCGTCACATTGGTGATTGTGCCGATGCTGGCCCATGGCAACGAGATGGCGCGCTATCACGATCTGCTGTGGCTGGG
CGCCGCAGGTCTGGTTTGCTCCGGCATCGCGGCGCTGTTCGTCGGCCCGATGCGGTCTGTGTCCGTCACAACCGCCACCC
GAATGCCACTGCGGGAAATCTATTGGATGGGCTTCGCGATCGCCCGCTCCCAGCCGTGGTTTCGCCGGTATATGACGACT
TACCTGCTGTTCGTTCCGATCAGCCTGGGCACCACGTTCTTCAGCCTGCGCGCCGCCCAGTCCAACGGCAGTCTGCACGT
GCTGGTGATCCTTTCCAGCATTGGATTGGTCGTCGGTTCGATGCTGTGGCGACAGATAAACCGCCTGTTCGGGGTGCGTG
GCCTGCTGCTGGGCAGCGCACTGCTCAACGCCGCTGCTGCGCTGCTGTGCATGGTGGCCGAGTCGTGTGGGCAGTGGGTT
CACGCCTGGGCGTACGGCACGGCGTTCCTGCTGGCTACGGTGGCCGCTCAAACGGTGGTCGCCGCATCGATATCGTGGAT
CAGCGTCCTCGCGCCCGAGCGGTACCGCGCCACCCTGATCTGCGTTGGGTCGACCTTGGCCGCCGTCGAAGCCACCGTGC
TGGGAGTTGCGCTCGGCGGAATTGCCCAAAAGCATGCCACCATCTGGCCGGTTGTCGTCGTGCTGACACTGGCCGTAATC
GCCGCGGTGGCGAGTCTGCGCGCACCGACACGAATCGGGGTGACGGCGGACACGAGCCCGCAAGCAGCGACCTTGCAAGC
CTACCGCCCGGCCACTCCTAACCCCATCCATAGCGATGAACGTTCGACGCCGCCCGACCATCTCTCAGTCCGCCGCGGGC
AGTTACGACACGTATGGGACAGTCGCCGGCCCGCGCCACCCCTGAACCGGCCAAGCTGTCGCCGCGCGGCCCGCCGTCCA
GCGCCCGGCAAACCCGCTGCCGCACTACCCCAGCCGCGCCATCCAGCCGTGGGTGTCCGCGAAGGTGCCCCGCTGGATGC
CGGTCAGCGTATCGCGTAG

Upstream 100 bases:

>100_bases
GCTCCCCTCCGTGTCCCCAGATTAGGGGACATGAAATTCAACCGACGGTGTCCGATTGGCGGATCGTTTTGGCCGCGCGG
CATATATAGCGTCGTTAATC

Downstream 100 bases:

>100_bases
TGCCATGGTCACCTCACCCGGCTGACCGTCGGCGATTCTGAACTCGCTGGCACCGTGCCGCACCCGCGCGACCGGGGTGA
TGACAGCGGCGGTGCCGCAC

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MPASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAFCIGAILGNSLSPLILQRAGQ
LRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGAGGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLA
TGVTLVIVPMLAHGNEMARYHDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSALLNAAAALLCMVAESCGQWV
HAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLICVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVI
AAVASLRAPTRIGVTADTSPQAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA

Sequences:

>Translated_512_residues
MPASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAFCIGAILGNSLSPLILQRAGQ
LRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGAGGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLA
TGVTLVIVPMLAHGNEMARYHDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSALLNAAAALLCMVAESCGQWV
HAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLICVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVI
AAVASLRAPTRIGVTADTSPQAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA
>Mature_511_residues
PASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAFCIGAILGNSLSPLILQRAGQL
RHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGAGGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLAT
GVTLVIVPMLAHGNEMARYHDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTTY
LLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSALLNAAAALLCMVAESCGQWVH
AWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLICVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVIA
AVASLRAPTRIGVTADTSPQAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRPA
PGKPAAALPQPRHPAVGVREGAPLDAGQRIA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y2209_MYCTU (P64953)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   B70786
- RefSeq:   NP_216725.1
- RefSeq:   NP_336737.1
- ProteinModelPortal:   P64953
- EnsemblBacteria:   EBMYCT00000001399
- EnsemblBacteria:   EBMYCT00000069247
- GeneID:   887230
- GeneID:   924160
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2265
- KEGG:   mtu:Rv2209
- TIGR:   MT2265
- TubercuList:   Rv2209
- GeneTree:   EBGT00050000018700
- HOGENOM:   HBG569379
- OMA:   CHASAHR
- ProtClustDB:   CLSK790378
- InterPro:   IPR016196

Pfam domain/function: SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 53580; Mature: 53448

Theoretical pI: Translated: 11.63; Mature: 11.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16928b14)-; HASH(0x1716d098)-; HASH(0x1425dff0)-; HASH(0x16e3dd9c)-; HASH(0x16d2a644)-; HASH(0x16f145c4)-; HASH(0x16705fa8)-; HASH(0x169083e4)-; HASH(0x1578a984)-; HASH(0x17130f5c)-; HASH(0x16d46fb4)-; HASH(0x170f3e9c)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAF
CCHHHHHHHHCCHHHHHHHHHHCCCEEEECEEECCCCCHHHHHHHCCCCHHHHHHHHHHH
CIGAILGNSLSPLILQRAGQLRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
GGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLATGVTLVIVPMLAHGNEMARY
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHH
HDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSA
HHHHHHHHHCCHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLNAAAALLCMVAESCGQWVHAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
CVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVIAAVASLRAPTRIGVTADTSP
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEECCCCC
QAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
CCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure 
PASRLVRQVSAPRNLFGRLVAQGGFYTAGLQLGSGAVVLPVICAHQGLTWAAGLLYPAF
CHHHHHHHHCCHHHHHHHHHHCCCEEEECEEECCCCCHHHHHHHCCCCHHHHHHHHHHH
CIGAILGNSLSPLILQRAGQLRHLLMAAISATAAALVVCNAAVPWTGVGVAAVFLATTGA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
GGVVTGVSSVAYTDMISSMLPAVRRGELLLTQGAAGSVLATGVTLVIVPMLAHGNEMARY
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHH
HDLLWLGAAGLVCSGIAALFVGPMRSVSVTTATRMPLREIYWMGFAIARSQPWFRRYMTT
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
YLLFVPISLGTTFFSLRAAQSNGSLHVLVILSSIGLVVGSMLWRQINRLFGVRGLLLGSA
HHHHHHHHHCCHHHHEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLNAAAALLCMVAESCGQWVHAWAYGTAFLLATVAAQTVVAASISWISVLAPERYRATLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
CVGSTLAAVEATVLGVALGGIAQKHATIWPVVVVLTLAVIAAVASLRAPTRIGVTADTSP
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEECCCCC
QAATLQAYRPATPNPIHSDERSTPPDHLSVRRGQLRHVWDSRRPAPPLNRPSCRRAARRP
CCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
APGKPAAALPQPRHPAVGVREGAPLDAGQRIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036