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The map label for this gene is trcR [H]

Identifier: 121636963

GI number: 121636963

Start: 1188448

End: 1189221

Strand: Reverse

Name: trcR [H]

Synonym: BCG_1091c

Alternate gene names: 121636963

Gene position: 1189221-1188448 (Counterclockwise)

Preceding gene: 121636964

Following gene: 121636962

Centisome position: 27.19

GC content: 62.02

Gene sequence:

>774_bases
ATGACGACGATGTCGGGGTACACGCGCAGTCAACGTCCGCGGCAAGCCATCCTGGGGCAGCTGCCACGGATTCATCGCGC
GGATGGATCACCGATCCGGGTGTTGTTGGTCGATGACGAACCAGCGCTGACCAATCTGGTCAAGATGGCGCTGCACTACG
AAGGCTGGGATGTCGAAGTCGCCCACGACGGGCAAGAGGCCATAGCCAAGTTCGACAAGGTCGGCCCCGATGTGCTGGTC
CTCGACATCATGCTTCCCGATGTGGACGGGTTGGAAATCCTGCGACGGGTCCGAGAATCCGACGTCTACACACCCACGCT
GTTCCTCACCGCGCGCGATTCCGTGATGGACCGGGTCACCGGTCTGACCTCGGGCGCCGACGACTACATGACAAAGCCGT
TCAGCCTCGAGGAGCTGGTCGCCCGGTTGCGCGGGTTGCTGCGCCGCTCCAGCCATCTGGAAAGGCCCGCCGATGAGGCA
CTCCGGGTCGGAGACCTTACGCTCGACGGGGCCAGCCGGGAGGTAACCCGCGACGGTACGCCGATCTCGCTCTCCTCGAC
CGAGTTCGAACTGCTTCGATTCCTGATGCGCAATCCCCGACGAGCACTGAGCCGTACCGAGATCCTGGATCGGGTTTGGA
ACTACGACTTCGCAGGCCGCACCAGCATTGTCGACCTGTATATCTCCTATCTGAGGAAGAAGATCGACTCCGACCGGGAG
CCAATGATCCATACGGTCCGCGGCATTGGATACATGCTGCGTCCGCCGGAATGA

Upstream 100 bases:

>100_bases
TTTTCAGGCCGAAGTAACTACATAAGCGACATTTGAAAAATTTATGAATCCCGTGACAACTGCATGTGCGCTTGCACAGG
ACTTGAGAGGATACGGGAGC

Downstream 100 bases:

>100_bases
GCCTGGCATGATCCCGGACCGAAACACTCGGTCCAGAAAAGCCCCCTGCTGGCGACCCCGCTCGTTACGCCAGCAATTGC
TGCTCGGCGTGTTGGCGGTC

Product: two component transcriptional regulator trcR

Products: NA

Alternate protein names: Mycobacterial persistence regulator A [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLV
LDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEA
LRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE
PMIHTVRGIGYMLRPPE

Sequences:

>Translated_257_residues
MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLV
LDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEA
LRVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE
PMIHTVRGIGYMLRPPE
>Mature_256_residues
TTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEVAHDGQEAIAKFDKVGPDVLVL
DIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVTGLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEAL
RVGDLTLDGASREVTRDGTPISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDREP
MIHTVRGIGYMLRPPE

Specific function: Member of the two-component regulatory system mprB/mprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a tr

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=41.4096916299559, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=39.1891891891892, Blast_Score=150, Evalue=7e-38,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=40.7079646017699, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=36.4864864864865, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=38.4615384615385, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=36.7256637168142, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=35.4260089686099, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=39.4736842105263, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=35.4545454545455, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=33.4782608695652, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=34.5132743362832, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=31.7180616740088, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.4763948497854, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788550, Length=162, Percent_Identity=30.8641975308642, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=33.9130434782609, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=31.4814814814815, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29210; Mature: 29079

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEE
AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT
ECCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT
HCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEECCCCCCCCCCCC
PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE
CEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
PMIHTVRGIGYMLRPPE
HHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTMSGYTRSQRPRQAILGQLPRIHRADGSPIRVLLVDDEPALTNLVKMALHYEGWDVEV
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEE
AHDGQEAIAKFDKVGPDVLVLDIMLPDVDGLEILRRVRESDVYTPTLFLTARDSVMDRVT
ECCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHH
GLTSGADDYMTKPFSLEELVARLRGLLRRSSHLERPADEALRVGDLTLDGASREVTRDGT
HCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEECCCCCCCCCCCC
PISLSSTEFELLRFLMRNPRRALSRTEILDRVWNYDFAGRTSIVDLYISYLRKKIDSDRE
CEEECCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
PMIHTVRGIGYMLRPPE
HHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA