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The map label for this gene is lnt [H]

Identifier: 120612821

GI number: 120612821

Start: 4636282

End: 4637886

Strand: Reverse

Name: lnt [H]

Synonym: Aave_4184

Alternate gene names: 120612821

Gene position: 4637886-4636282 (Counterclockwise)

Preceding gene: 120612822

Following gene: 120612819

Centisome position: 86.64

GC content: 73.64

Gene sequence:

>1605_bases
ATGCTCCTGCAAGCCTATGGCAACGGGCGCCCGCGCGCGCCCGCGGCGCTCCTGTTGACGGCAGCCGTGCTGGCCGGGCT
GGCGCAGGCGGCTTCCATCGCCTGGCCCTGGGGCGGCGAGCCGCTCTGGTGGCTGCAGCTCGCCTCGCTGGCAGCCTTCG
CGCGCGTCCTGCTGTGGGCGCGCGGGGCAGGGCAGGGGGCCGGTCTCGGCGCCGCCTTCGCCACGGCCTGGCTCGCGGGC
ACCTTCTGGTGGCTGTTCATTTCCATGCACACCTACGGCGGCCTGGCGGCGCCGCTGGCCGCACTGGCGGTGCTGGCGCT
GGCAGCCTTCCTGGGCAGTTACTACGCGGCCGCGTCGGCGGTGTTCGTGCATCTGCGCGACCGCCTTCCGCGCCGCAGGG
GCTGGCAGGCCGCCTCCTTCGCCGCGCTCTGGCTGCTGGCCGAACTGGCGCGCGGCGTGTGGTGGACCGGTTTCCCCTGG
GGCGCCGGCGGATATGCGCACGTCGAGGGGCCCTTGCGGGTGCTCGCGCGCTGGGTGGGGGTGTATGGCATCGGCGCCGT
GGCGGCCCTGCTGGCGATGCTGGCCGTGCAGTTGCGCATCGCCGATCTGCGCCGTCCCCGGTGCTGGGCCGCGGCCGTGG
CGCTGGCATGCGCCTGGGCGGGGTTGGCCGCGCAGCGCCACTGCGCGGTGGATCGCTGCGGCACGCCGGTGGCCGCAGCC
CCCTCCCTGCTGTCCGTGGCGCTGTTGCAGGGCAATATCCCGCAGGACGAGAAATTCCAGGCCGGCAGCGGCGTGCCCAT
GGCCCTGCGCTGGTACGGCGATGCGTTGCGCGAAGCGGATGCCGCTCTGGTCGTGGCGCCGGAGACCGCCATCCCGCTGT
TGCCCCAGCAGCTGGTGCCGGGCTACCTGGAGTCCATCGCGGAGCGTTTCACCCGCAGCGGCCCGCGGGGCGGCCGGGCC
GCGCTGATCGGCATCCCGCTGGGCGACCCGCAGCGGGGCTATACGAACTCCGTCATCGGTTACGCGCCGGGCGGGACGGC
GCCCTACCAATATGACAAGCACCACCTCGTGCCGTTCGGGGAGTTCGTCCCGCCGTTCTTCCGGTGGTTCACCGAACTGA
TGAACATCCCGCTGGGTGATTTCAACCGGGGCGGCATGGTCCAGGCGCCCTTCGCCTGGGCCGGGCAGCGCCTGGCGCCG
AACATCTGCTACGAGGATCTGTTCGGCGAGGAGCTGGCCGCGCGCTTCGCGGACCGCGCCGCCGCCCCGACGGTGTTCAT
CAACCTGAGCAACATCGCCTGGTTCGGCGATTCCGTGGCCATCGACCAGCACCTGGCGATCAGCCGCATGCGGGCGCTGG
AATTCGAGCGGCCGATGGTGCGCGCCACCAACACCGGCGCCACCGCGCTGATCGACCACCGCGGCGTGGTGGCCGCGCGC
CTGCCCTCGGTGCAGCGCGGCATCCTGCGCGGCGAGGTGGAGGGGCGCGACGGGCCGCCCACCCCGTTCGCCTGGTGGGC
GGCACGGGCCGGATTGTGGCCGCTGTGGCTGCTGGGCGGGCTGGTGGTGGCCGCGGCGTTCGCGCTGCGCTCCCGCGGAC
GCTGA

Upstream 100 bases:

>100_bases
GCGGCCTGCGCTTCGTCGTGCTGCACACCAAGGGCGGCGCGGTGCGCTGGTTCAAGGTGTCGCCGCAGCCCCCGGGCGCC
GAACCGGACGCCGGCTGACC

Downstream 100 bases:

>100_bases
TACCACGGCATGGGGCCACGGCCGCCGGCCGGCGCCCGGCGTCGCCCCGGATCAGCCGCCGGATGGCACCGGCTGCTCCG
CCGAGGGCGCGCGCCCCAGC

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MLLQAYGNGRPRAPAALLLTAAVLAGLAQAASIAWPWGGEPLWWLQLASLAAFARVLLWARGAGQGAGLGAAFATAWLAG
TFWWLFISMHTYGGLAAPLAALAVLALAAFLGSYYAAASAVFVHLRDRLPRRRGWQAASFAALWLLAELARGVWWTGFPW
GAGGYAHVEGPLRVLARWVGVYGIGAVAALLAMLAVQLRIADLRRPRCWAAAVALACAWAGLAAQRHCAVDRCGTPVAAA
PSLLSVALLQGNIPQDEKFQAGSGVPMALRWYGDALREADAALVVAPETAIPLLPQQLVPGYLESIAERFTRSGPRGGRA
ALIGIPLGDPQRGYTNSVIGYAPGGTAPYQYDKHHLVPFGEFVPPFFRWFTELMNIPLGDFNRGGMVQAPFAWAGQRLAP
NICYEDLFGEELAARFADRAAAPTVFINLSNIAWFGDSVAIDQHLAISRMRALEFERPMVRATNTGATALIDHRGVVAAR
LPSVQRGILRGEVEGRDGPPTPFAWWAARAGLWPLWLLGGLVVAAAFALRSRGR

Sequences:

>Translated_534_residues
MLLQAYGNGRPRAPAALLLTAAVLAGLAQAASIAWPWGGEPLWWLQLASLAAFARVLLWARGAGQGAGLGAAFATAWLAG
TFWWLFISMHTYGGLAAPLAALAVLALAAFLGSYYAAASAVFVHLRDRLPRRRGWQAASFAALWLLAELARGVWWTGFPW
GAGGYAHVEGPLRVLARWVGVYGIGAVAALLAMLAVQLRIADLRRPRCWAAAVALACAWAGLAAQRHCAVDRCGTPVAAA
PSLLSVALLQGNIPQDEKFQAGSGVPMALRWYGDALREADAALVVAPETAIPLLPQQLVPGYLESIAERFTRSGPRGGRA
ALIGIPLGDPQRGYTNSVIGYAPGGTAPYQYDKHHLVPFGEFVPPFFRWFTELMNIPLGDFNRGGMVQAPFAWAGQRLAP
NICYEDLFGEELAARFADRAAAPTVFINLSNIAWFGDSVAIDQHLAISRMRALEFERPMVRATNTGATALIDHRGVVAAR
LPSVQRGILRGEVEGRDGPPTPFAWWAARAGLWPLWLLGGLVVAAAFALRSRGR
>Mature_534_residues
MLLQAYGNGRPRAPAALLLTAAVLAGLAQAASIAWPWGGEPLWWLQLASLAAFARVLLWARGAGQGAGLGAAFATAWLAG
TFWWLFISMHTYGGLAAPLAALAVLALAAFLGSYYAAASAVFVHLRDRLPRRRGWQAASFAALWLLAELARGVWWTGFPW
GAGGYAHVEGPLRVLARWVGVYGIGAVAALLAMLAVQLRIADLRRPRCWAAAVALACAWAGLAAQRHCAVDRCGTPVAAA
PSLLSVALLQGNIPQDEKFQAGSGVPMALRWYGDALREADAALVVAPETAIPLLPQQLVPGYLESIAERFTRSGPRGGRA
ALIGIPLGDPQRGYTNSVIGYAPGGTAPYQYDKHHLVPFGEFVPPFFRWFTELMNIPLGDFNRGGMVQAPFAWAGQRLAP
NICYEDLFGEELAARFADRAAAPTVFINLSNIAWFGDSVAIDQHLAISRMRALEFERPMVRATNTGATALIDHRGVVAAR
LPSVQRGILRGEVEGRDGPPTPFAWWAARAGLWPLWLLGGLVVAAAFALRSRGR

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=490, Percent_Identity=31.4285714285714, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57175; Mature: 57175

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQAYGNGRPRAPAALLLTAAVLAGLAQAASIAWPWGGEPLWWLQLASLAAFARVLLWA
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RGAGQGAGLGAAFATAWLAGTFWWLFISMHTYGGLAAPLAALAVLALAAFLGSYYAAASA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVHLRDRLPRRRGWQAASFAALWLLAELARGVWWTGFPWGAGGYAHVEGPLRVLARWVG
HHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCEECCHHHHHHHHHHH
VYGIGAVAALLAMLAVQLRIADLRRPRCWAAAVALACAWAGLAAQRHCAVDRCGTPVAAA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
PSLLSVALLQGNIPQDEKFQAGSGVPMALRWYGDALREADAALVVAPETAIPLLPQQLVP
HHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCH
GYLESIAERFTRSGPRGGRAALIGIPLGDPQRGYTNSVIGYAPGGTAPYQYDKHHLVPFG
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCH
EFVPPFFRWFTELMNIPLGDFNRGGMVQAPFAWAGQRLAPNICYEDLFGEELAARFADRA
HHCCHHHHHHHHHHCCCCCCCCCCCEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
AAPTVFINLSNIAWFGDSVAIDQHLAISRMRALEFERPMVRATNTGATALIDHRGVVAAR
CCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHCCCHHEECCCCCEEEEECCCHHHHH
LPSVQRGILRGEVEGRDGPPTPFAWWAARAGLWPLWLLGGLVVAAAFALRSRGR
CCHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLQAYGNGRPRAPAALLLTAAVLAGLAQAASIAWPWGGEPLWWLQLASLAAFARVLLWA
CEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RGAGQGAGLGAAFATAWLAGTFWWLFISMHTYGGLAAPLAALAVLALAAFLGSYYAAASA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVHLRDRLPRRRGWQAASFAALWLLAELARGVWWTGFPWGAGGYAHVEGPLRVLARWVG
HHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCCCEECCHHHHHHHHHHH
VYGIGAVAALLAMLAVQLRIADLRRPRCWAAAVALACAWAGLAAQRHCAVDRCGTPVAAA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
PSLLSVALLQGNIPQDEKFQAGSGVPMALRWYGDALREADAALVVAPETAIPLLPQQLVP
HHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCHHHCH
GYLESIAERFTRSGPRGGRAALIGIPLGDPQRGYTNSVIGYAPGGTAPYQYDKHHLVPFG
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCH
EFVPPFFRWFTELMNIPLGDFNRGGMVQAPFAWAGQRLAPNICYEDLFGEELAARFADRA
HHCCHHHHHHHHHHCCCCCCCCCCCEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
AAPTVFINLSNIAWFGDSVAIDQHLAISRMRALEFERPMVRATNTGATALIDHRGVVAAR
CCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHCCCHHEECCCCCEEEEECCCHHHHH
LPSVQRGILRGEVEGRDGPPTPFAWWAARAGLWPLWLLGGLVVAAAFALRSRGR
CCHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA