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The map label for this gene is gltJ [H]

Identifier: 120612709

GI number: 120612709

Start: 4523791

End: 4524522

Strand: Reverse

Name: gltJ [H]

Synonym: Aave_4072

Alternate gene names: 120612709

Gene position: 4524522-4523791 (Counterclockwise)

Preceding gene: 120612710

Following gene: 120612708

Centisome position: 84.53

GC content: 64.62

Gene sequence:

>732_bases
ATGGGATCGAATTGGGATTGGCAGGTCTTCCTGCAGGACCCGGGGGGCGATTATCCGACCTACCTCCAGTGGATGCTATC
GGCCTGGGGCTGGACCGTGTCGGTGGCCCTGCTGGCGCTGGTGATCGCGCTGGTGGCGGGCTCGGTCATCGGCACGCTGC
GCACGCTGCCGGACAACAGGTTTCTGGTCGGCTTCGGCAACGCGTGGGTGGAACTGTTCCGCAACATCCCCCTGCTGGTG
CAGATTTTCCTGTGGTACCACGTGGTGCCTGCCATCTTCCCCGTGATGAAGAGCGTTTCCGGCTTCATCCTGGTGGTGCT
GGCGCTGGGGTTCTTCACGTCGGCGCGGATCGCCGAACAGGTGCGCTCGGGCATCCAGGCCCTGCCGCGCGGCCAGCGCT
ATGCCGGCATGGCGCTGGGCTTCACCACCGTGCAGTACTACCGCTACGTGCTGCTGCCCATGGCATTCCGCATCATCCTG
CCGCCGCTGACCAGCGAGACGATGAACATCTTCAAGAACTCGTCGGTGGCCTTCGCCGTGTCGGTGACCGAACTGACCAT
GTTCGCCATGCAGGCGCAGGAAGAAACCTCGCGCGGCATCGAAATCTATCTGGCGGTGACGGGCCTGTACGTCGTCTCGG
CCTTCGCCATCAACCGCATCATGGCCTTCATCGAAAAGCGCGCGCGCGTCCCGGGCTTCATCGTCGCGGGCGGCACGGGG
GGAGGCCACTGA

Upstream 100 bases:

>100_bases
GAACGCCCACCTCGCCGGTGGGCGTTTGCTTGTTGTCCCGCTGCGGCGGGCGGACGGCCGTCGGTTTTCAGGACGTATGA
CGATTTGAGAAGGAATTCCC

Downstream 100 bases:

>100_bases
CATGATGAATCTCGACTTTTCCTTCTACAGCTGGGACATCATCAGCAAGTTCGTCGTCAAGGGCTTCTATTTCAGCTTCA
TGCTGACGCTGATCGCCACG

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MGSNWDWQVFLQDPGGDYPTYLQWMLSAWGWTVSVALLALVIALVAGSVIGTLRTLPDNRFLVGFGNAWVELFRNIPLLV
QIFLWYHVVPAIFPVMKSVSGFILVVLALGFFTSARIAEQVRSGIQALPRGQRYAGMALGFTTVQYYRYVLLPMAFRIIL
PPLTSETMNIFKNSSVAFAVSVTELTMFAMQAQEETSRGIEIYLAVTGLYVVSAFAINRIMAFIEKRARVPGFIVAGGTG
GGH

Sequences:

>Translated_243_residues
MGSNWDWQVFLQDPGGDYPTYLQWMLSAWGWTVSVALLALVIALVAGSVIGTLRTLPDNRFLVGFGNAWVELFRNIPLLV
QIFLWYHVVPAIFPVMKSVSGFILVVLALGFFTSARIAEQVRSGIQALPRGQRYAGMALGFTTVQYYRYVLLPMAFRIIL
PPLTSETMNIFKNSSVAFAVSVTELTMFAMQAQEETSRGIEIYLAVTGLYVVSAFAINRIMAFIEKRARVPGFIVAGGTG
GGH
>Mature_242_residues
GSNWDWQVFLQDPGGDYPTYLQWMLSAWGWTVSVALLALVIALVAGSVIGTLRTLPDNRFLVGFGNAWVELFRNIPLLVQ
IFLWYHVVPAIFPVMKSVSGFILVVLALGFFTSARIAEQVRSGIQALPRGQRYAGMALGFTTVQYYRYVLLPMAFRIILP
PLTSETMNIFKNSSVAFAVSVTELTMFAMQAQEETSRGIEIYLAVTGLYVVSAFAINRIMAFIEKRARVPGFIVAGGTGG
GH

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786874, Length=242, Percent_Identity=41.7355371900826, Blast_Score=197, Evalue=4e-52,
Organism=Escherichia coli, GI48994930, Length=124, Percent_Identity=38.7096774193548, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786873, Length=211, Percent_Identity=26.5402843601896, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787030, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788226, Length=211, Percent_Identity=28.436018957346, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87082239, Length=161, Percent_Identity=27.3291925465839, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788645, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787086, Length=224, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26843; Mature: 26712

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSNWDWQVFLQDPGGDYPTYLQWMLSAWGWTVSVALLALVIALVAGSVIGTLRTLPDNR
CCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FLVGFGNAWVELFRNIPLLVQIFLWYHVVPAIFPVMKSVSGFILVVLALGFFTSARIAEQ
EEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRSGIQALPRGQRYAGMALGFTTVQYYRYVLLPMAFRIILPPLTSETMNIFKNSSVAFAV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEE
SVTELTMFAMQAQEETSRGIEIYLAVTGLYVVSAFAINRIMAFIEKRARVPGFIVAGGTG
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GGH
CCC
>Mature Secondary Structure 
GSNWDWQVFLQDPGGDYPTYLQWMLSAWGWTVSVALLALVIALVAGSVIGTLRTLPDNR
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FLVGFGNAWVELFRNIPLLVQIFLWYHVVPAIFPVMKSVSGFILVVLALGFFTSARIAEQ
EEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRSGIQALPRGQRYAGMALGFTTVQYYRYVLLPMAFRIILPPLTSETMNIFKNSSVAFAV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEE
SVTELTMFAMQAQEETSRGIEIYLAVTGLYVVSAFAINRIMAFIEKRARVPGFIVAGGTG
HHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
GGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]