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The map label for this gene is bioD [H]

Identifier: 120612483

GI number: 120612483

Start: 4270372

End: 4270956

Strand: Direct

Name: bioD [H]

Synonym: Aave_3842

Alternate gene names: 120612483

Gene position: 4270372-4270956 (Clockwise)

Preceding gene: 120612482

Following gene: 120612484

Centisome position: 79.78

GC content: 74.87

Gene sequence:

>585_bases
ATGAAGGCCGTCGCCGCAGGCGCGGAACCCATCGGCCCCGGCGGCGCGCTCGCCAACGAGGATGTGCTGGCCCTGCGCGC
CGCCTCCACGATCCAGGTGGCGCCCGCGCTGGACAATCCCGTGCTGCTGCCCGACCCGCTCTCGCCGCACATCGCCGCGC
GGCGTGCGGGCACGCGCATCGACATCGCCGCCATCGTGCAGGCCTTCAGAGCGCTCGCCGCGCAGGCCGATGCCGTCGTG
GTGGAAGGGGCCGGCGGCTTCCACGTGCCGCTCTCGGACACGGAAAACGGTGCCGACCTGGCCCAGGCGCTCGGCCTGCC
CGTGGTGCTCGTCGTGGGCCTGCGCCTGGGGTGCCTCAGCCACGCGGCGCTCACGGCCGATGCCATCCGCGCGCGCGGAT
TGCCGCTCGCCGGCTGGATCGCCAGCCGCATCGACCCCTCCATGCTGGCCGCGGAGGACAATATCGCCTGGCTGCGCCAG
CGCCTGCGGGCGCCCCTGCTCGCAGACATCCCGCACCAGCGGCAGCCCGACCCGCGCGCCACGCCGTTCGCGCTGCCCGA
CTCCTGGACCACGCCCTCCGCATGA

Upstream 100 bases:

>100_bases
CGGCTGCTTCGTCACCGGCACCGACACCGGCGTGGGCAAGACCCTCGCCAGCGCCGGCCTGCTGCACGCGCTCGCGCGGC
ACCATGCGCGCGTGGTCGGC

Downstream 100 bases:

>100_bases
CGACCTTTCCCTTCGCTCCCTCCTGGCTCGACGAACTGCCCGCCCGCCTGGCGGAACTCGACGCCGTCCACCTGCGCCGC
CGCCGGCGCACGGTGCGGCC

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKAVAAGAEPIGPGGALANEDVLALRAASTIQVAPALDNPVLLPDPLSPHIAARRAGTRIDIAAIVQAFRALAAQADAVV
VEGAGGFHVPLSDTENGADLAQALGLPVVLVVGLRLGCLSHAALTADAIRARGLPLAGWIASRIDPSMLAAEDNIAWLRQ
RLRAPLLADIPHQRQPDPRATPFALPDSWTTPSA

Sequences:

>Translated_194_residues
MKAVAAGAEPIGPGGALANEDVLALRAASTIQVAPALDNPVLLPDPLSPHIAARRAGTRIDIAAIVQAFRALAAQADAVV
VEGAGGFHVPLSDTENGADLAQALGLPVVLVVGLRLGCLSHAALTADAIRARGLPLAGWIASRIDPSMLAAEDNIAWLRQ
RLRAPLLADIPHQRQPDPRATPFALPDSWTTPSA
>Mature_194_residues
MKAVAAGAEPIGPGGALANEDVLALRAASTIQVAPALDNPVLLPDPLSPHIAARRAGTRIDIAAIVQAFRALAAQADAVV
VEGAGGFHVPLSDTENGADLAQALGLPVVLVVGLRLGCLSHAALTADAIRARGLPLAGWIASRIDPSMLAAEDNIAWLRQ
RLRAPLLADIPHQRQPDPRATPFALPDSWTTPSA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=171, Percent_Identity=43.859649122807, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI87081944, Length=179, Percent_Identity=34.0782122905028, Blast_Score=97, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 19970; Mature: 19970

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVAAGAEPIGPGGALANEDVLALRAASTIQVAPALDNPVLLPDPLSPHIAARRAGTRI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCEECCCCCCHHHHHHHCCCEE
DIAAIVQAFRALAAQADAVVVEGAGGFHVPLSDTENGADLAQALGLPVVLVVGLRLGCLS
CHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
HAALTADAIRARGLPLAGWIASRIDPSMLAAEDNIAWLRQRLRAPLLADIPHQRQPDPRA
HHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCHHHCCCCCCCCCCCC
TPFALPDSWTTPSA
CCCCCCCCCCCCCC
>Mature Secondary Structure
MKAVAAGAEPIGPGGALANEDVLALRAASTIQVAPALDNPVLLPDPLSPHIAARRAGTRI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCEECCCCCCHHHHHHHCCCEE
DIAAIVQAFRALAAQADAVVVEGAGGFHVPLSDTENGADLAQALGLPVVLVVGLRLGCLS
CHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
HAALTADAIRARGLPLAGWIASRIDPSMLAAEDNIAWLRQRLRAPLLADIPHQRQPDPRA
HHHHHHHHHHHCCCCHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCHHHCCCCCCCCCCCC
TPFALPDSWTTPSA
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA