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The map label for this gene is ampR [H]

Identifier: 120612323

GI number: 120612323

Start: 4055961

End: 4056893

Strand: Direct

Name: ampR [H]

Synonym: Aave_3679

Alternate gene names: 120612323

Gene position: 4055961-4056893 (Clockwise)

Preceding gene: 120612320

Following gene: 120612324

Centisome position: 75.77

GC content: 66.13

Gene sequence:

>933_bases
ATGAAGATCCGTTCTCCGTCCCTGGTTGAGCTGCACGCTTTCCTGGCGGTGTGCCGGCACATTAGCTTTCGTCGGGCCGC
GGATGAGCTTTGCGTGACTCCGGCGGCGGTAAGCCGCGCAGTCCTGCGGCTGGAAGAGCACCTGGCCGGAGTCCGGCTCT
TCGAGCGCTCCGCCACGGGCGTCAAGCTGACTGCCGGGGGCTTGCAACTGCGCAATCTCACGGAGCGGCATGTACTCGCA
CTGGAGTCCGCCGCGGAAACGATCGGGCGCCTGGCCCAACCGCGGCGGGTCCGGCTGAGCATCATTCCCACCTTGAGCAT
CCAGTGGCTCATGCCCCGGCTGCCTCTCTTCAAGGAGGTCCACCAGGACATAGACATCGAGTTGCGCCAGTTCAAGCACG
ACGAGGATTTCACGCGCGACGATGTTGACCTGTGGGTCGAGGTAAAGCGCCCTCGCCGTCGGTGGCCCGACCACATCCGC
ACCCATTACCTGCTGGGCCGGGAGTTCATACCCGTCTGCGCGCCCCATCTGGGCAAGAAGTACCGCGAGCCGGCGGACCT
CCAGGTGGCGACGCTGCTGCACCACACCAACTTCCCGGATAACTGGGAACGGTGGTTCGCGAAGGCGGGGGCGCCGTGCC
AGCCTCGGCTGGGGCCGGGGTTCGATCTCACGATGCATCTGATCATCGCAGCGAAGGCAGGGATGGGGATCGCGGTGGTG
CCCGGGTGCCTGGTCGAGCGGGAGTTGTCGACAGGCGAACTCGTGATGCCGTTCGACATCCCCGTGTCATGCGGCCGGGG
CTACTTCATCTGCTGGAAACGCAACAGTCCGCCCTTCTCAGCCCAGGAGACATTCGCGGCCTGGCTGGCAGAACAGGCCG
GCACGCCCGTGGGCCCTGACCGCCACGAAACCCGGCCAGCCGGGGAGCCCTGA

Upstream 100 bases:

>100_bases
TGCTCGTTCCTCGGTGAAGAAGCCGCGAGATTACGGAGGCAGGACGCATGGGACAAACGACAAATTCATCACGGGTGTTG
ACATGATGTAATCGCCCGCC

Downstream 100 bases:

>100_bases
CCTCAGGCGCATTCGCCGCCGGGGCAATCGGGCCTCACCCTGAACGCGGCATGGCGGACCCTGGCAGGCCGGGCAGGCGA
ACTCCGGACGGGCCACTGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKIRSPSLVELHAFLAVCRHISFRRAADELCVTPAAVSRAVLRLEEHLAGVRLFERSATGVKLTAGGLQLRNLTERHVLA
LESAAETIGRLAQPRRVRLSIIPTLSIQWLMPRLPLFKEVHQDIDIELRQFKHDEDFTRDDVDLWVEVKRPRRRWPDHIR
THYLLGREFIPVCAPHLGKKYREPADLQVATLLHHTNFPDNWERWFAKAGAPCQPRLGPGFDLTMHLIIAAKAGMGIAVV
PGCLVERELSTGELVMPFDIPVSCGRGYFICWKRNSPPFSAQETFAAWLAEQAGTPVGPDRHETRPAGEP

Sequences:

>Translated_310_residues
MKIRSPSLVELHAFLAVCRHISFRRAADELCVTPAAVSRAVLRLEEHLAGVRLFERSATGVKLTAGGLQLRNLTERHVLA
LESAAETIGRLAQPRRVRLSIIPTLSIQWLMPRLPLFKEVHQDIDIELRQFKHDEDFTRDDVDLWVEVKRPRRRWPDHIR
THYLLGREFIPVCAPHLGKKYREPADLQVATLLHHTNFPDNWERWFAKAGAPCQPRLGPGFDLTMHLIIAAKAGMGIAVV
PGCLVERELSTGELVMPFDIPVSCGRGYFICWKRNSPPFSAQETFAAWLAEQAGTPVGPDRHETRPAGEP
>Mature_310_residues
MKIRSPSLVELHAFLAVCRHISFRRAADELCVTPAAVSRAVLRLEEHLAGVRLFERSATGVKLTAGGLQLRNLTERHVLA
LESAAETIGRLAQPRRVRLSIIPTLSIQWLMPRLPLFKEVHQDIDIELRQFKHDEDFTRDDVDLWVEVKRPRRRWPDHIR
THYLLGREFIPVCAPHLGKKYREPADLQVATLLHHTNFPDNWERWFAKAGAPCQPRLGPGFDLTMHLIIAAKAGMGIAVV
PGCLVERELSTGELVMPFDIPVSCGRGYFICWKRNSPPFSAQETFAAWLAEQAGTPVGPDRHETRPAGEP

Specific function: This protein is a positive regulator of gene expression of cephalosporinase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=277, Percent_Identity=34.2960288808664, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786448, Length=284, Percent_Identity=30.9859154929577, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788706, Length=307, Percent_Identity=30.2931596091205, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693193, Length=268, Percent_Identity=26.4925373134328, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35066; Mature: 35066

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRSPSLVELHAFLAVCRHISFRRAADELCVTPAAVSRAVLRLEEHLAGVRLFERSATG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VKLTAGGLQLRNLTERHVLALESAAETIGRLAQPRRVRLSIIPTLSIQWLMPRLPLFKEV
EEEEECCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCHHHHHH
HQDIDIELRQFKHDEDFTRDDVDLWVEVKRPRRRWPDHIRTHYLLGREFIPVCAPHLGKK
HHCCCHHHHHHCCCCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHCCHHHHHHCHHHHHH
YREPADLQVATLLHHTNFPDNWERWFAKAGAPCQPRLGPGFDLTMHLIIAAKAGMGIAVV
HCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHEEEHHHCCCCEEEC
PGCLVERELSTGELVMPFDIPVSCGRGYFICWKRNSPPFSAQETFAAWLAEQAGTPVGPD
CCHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
RHETRPAGEP
CCCCCCCCCC
>Mature Secondary Structure
MKIRSPSLVELHAFLAVCRHISFRRAADELCVTPAAVSRAVLRLEEHLAGVRLFERSATG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
VKLTAGGLQLRNLTERHVLALESAAETIGRLAQPRRVRLSIIPTLSIQWLMPRLPLFKEV
EEEEECCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHCCCHHHHHH
HQDIDIELRQFKHDEDFTRDDVDLWVEVKRPRRRWPDHIRTHYLLGREFIPVCAPHLGKK
HHCCCHHHHHHCCCCCCCCCCCEEEEEECCHHHCCHHHHHHHHHHCCHHHHHHCHHHHHH
YREPADLQVATLLHHTNFPDNWERWFAKAGAPCQPRLGPGFDLTMHLIIAAKAGMGIAVV
HCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHEEEHHHCCCCEEEC
PGCLVERELSTGELVMPFDIPVSCGRGYFICWKRNSPPFSAQETFAAWLAEQAGTPVGPD
CCHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCC
RHETRPAGEP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2788410 [H]