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The map label for this gene is ubiG

Identifier: 120611934

GI number: 120611934

Start: 3622659

End: 3623375

Strand: Reverse

Name: ubiG

Synonym: Aave_3278

Alternate gene names: 120611934

Gene position: 3623375-3622659 (Counterclockwise)

Preceding gene: 120611935

Following gene: 120611933

Centisome position: 67.69

GC content: 64.71

Gene sequence:

>717_bases
ATGAGCTCCTCCACTGCCAATGTCGATCCGGCCGAACTGGCCAAATTCTCCGAACTGGCCCACCGCTGGTGGGATCTCGA
AAGCGAATTCCGGCCCCTGCACGAGATCAATCCGCTGCGGCTGGGCTGGATCGATGGCCTGGCCCCACTGCAGGGACGGC
GGGTGCTGGACGTCGGCTGCGGCGGCGGCATCCTGGCCGACGCCATGGCCCGCAAGGGCGCGACGGTGACGGGCATCGAT
CTCGCCACCAAGTCGCTGAAGGTGGCCCAGCTCCATGCCCTGGAGGCCGGCACGCCCGATATCCAGTACCGCGAGGTCAG
CGTCGAGGCGCTGGCGGAAGAATCGCCCGCATCGTTCGACACCGTGACCTGCATGGAGATGCTGGAGCACGTTCCTGATC
CGGCGTCCGTGGTGCAGGCATGCGCGCGGCTGGTCAAGCCTGGCGGGTGGGTGTTTTTCTCGACCATCAACCGCAATGCG
AAGGCGTTTCTCCTGGCCATCGTGGGCGCTGAATATGTGCTGGGCATGCTGCCACGTGGAACACACGAATATGCGAAGCT
GATCAAACCCAGTGAACTGGCCACGGCCTGCCGCTCCGCACGGCTCGATGTCCTGCAGACCCGCGGCATGGAATACAACC
CCCTCACGCGCCGTTATGCATTGAGCGGGGATACCAGTGTGAATTACCTCATGGCCTGCCGCCGGGCGGAGGCGTGA

Upstream 100 bases:

>100_bases
GGCACCCGCGCCAACTGATTTCGGTCAGTTTCCCTTCCCTGAAAGCCCCGGTCTCCGGGGCTTTTTTTATGCCCGCGGCA
ATTGCGGGCACAATTTGCCA

Downstream 100 bases:

>100_bases
TGGCGGACATGCCTCCCTTTCCCTCGCGTGTGAGCGCGGTGCTGTTCGACCTCGACGGCACGCTGGTGGACAGCGCGCCG
GATCTCGCCGCGGCTGCCGA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSSSTANVDPAELAKFSELAHRWWDLESEFRPLHEINPLRLGWIDGLAPLQGRRVLDVGCGGGILADAMARKGATVTGID
LATKSLKVAQLHALEAGTPDIQYREVSVEALAEESPASFDTVTCMEMLEHVPDPASVVQACARLVKPGGWVFFSTINRNA
KAFLLAIVGAEYVLGMLPRGTHEYAKLIKPSELATACRSARLDVLQTRGMEYNPLTRRYALSGDTSVNYLMACRRAEA

Sequences:

>Translated_238_residues
MSSSTANVDPAELAKFSELAHRWWDLESEFRPLHEINPLRLGWIDGLAPLQGRRVLDVGCGGGILADAMARKGATVTGID
LATKSLKVAQLHALEAGTPDIQYREVSVEALAEESPASFDTVTCMEMLEHVPDPASVVQACARLVKPGGWVFFSTINRNA
KAFLLAIVGAEYVLGMLPRGTHEYAKLIKPSELATACRSARLDVLQTRGMEYNPLTRRYALSGDTSVNYLMACRRAEA
>Mature_237_residues
SSSTANVDPAELAKFSELAHRWWDLESEFRPLHEINPLRLGWIDGLAPLQGRRVLDVGCGGGILADAMARKGATVTGIDL
ATKSLKVAQLHALEAGTPDIQYREVSVEALAEESPASFDTVTCMEMLEHVPDPASVVQACARLVKPGGWVFFSTINRNAK
AFLLAIVGAEYVLGMLPRGTHEYAKLIKPSELATACRSARLDVLQTRGMEYNPLTRRYALSGDTSVNYLMACRRAEA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=241, Percent_Identity=39.0041493775934, Blast_Score=182, Evalue=3e-46,
Organism=Escherichia coli, GI1788564, Length=235, Percent_Identity=54.8936170212766, Blast_Score=269, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI115533050, Length=238, Percent_Identity=33.6134453781513, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324476, Length=274, Percent_Identity=30.6569343065693, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281365311, Length=260, Percent_Identity=30, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24585589, Length=212, Percent_Identity=33.9622641509434, Blast_Score=127, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_ACIAC (A1TSA0)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_971612.1
- ProteinModelPortal:   A1TSA0
- STRING:   A1TSA0
- GeneID:   4667819
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_3278
- NMPDR:   fig|397945.5.peg.2802
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   A1TSA0
- ProtClustDB:   PRK05134
- BioCyc:   AAVE397945:AAVE_3278-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 25930; Mature: 25799

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSTANVDPAELAKFSELAHRWWDLESEFRPLHEINPLRLGWIDGLAPLQGRRVLDVGC
CCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHCCCEEEECCCCCCCCCCCEEEEECC
GGGILADAMARKGATVTGIDLATKSLKVAQLHALEAGTPDIQYREVSVEALAEESPASFD
CCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCHH
TVTCMEMLEHVPDPASVVQACARLVKPGGWVFFSTINRNAKAFLLAIVGAEYVLGMLPRG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
THEYAKLIKPSELATACRSARLDVLQTRGMEYNPLTRRYALSGDTSVNYLMACRRAEA
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SSSTANVDPAELAKFSELAHRWWDLESEFRPLHEINPLRLGWIDGLAPLQGRRVLDVGC
CCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCHHHCCCEEEECCCCCCCCCCCEEEEECC
GGGILADAMARKGATVTGIDLATKSLKVAQLHALEAGTPDIQYREVSVEALAEESPASFD
CCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCHH
TVTCMEMLEHVPDPASVVQACARLVKPGGWVFFSTINRNAKAFLLAIVGAEYVLGMLPRG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
THEYAKLIKPSELATACRSARLDVLQTRGMEYNPLTRRYALSGDTSVNYLMACRRAEA
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA