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The map label for this gene is gufA [H]

Identifier: 120611331

GI number: 120611331

Start: 2923042

End: 2923944

Strand: Direct

Name: gufA [H]

Synonym: Aave_2663

Alternate gene names: 120611331

Gene position: 2923042-2923944 (Clockwise)

Preceding gene: 120611330

Following gene: 120611334

Centisome position: 54.61

GC content: 72.87

Gene sequence:

>903_bases
ATGCCCGCCCAGAACACGCTTTCACTGCGCCGCCCCATCTGGGGCCCCCGCCGCTGGCTGGGCCTGGCCATCGCCGTGGC
GGGCGCCGTGGTGCTGGCGCTGCAGTTCACGCAGTTCCTCCAGGCGAATCCGCGCGTGGCCCAGGCCTGGCAGGGCGGCC
TCGTCGCGGCGCTGGCGACGGCGCTGGGCACGCTGCCCGTGGTGTTCTCGCAGCGCCTGTCGGAACGCGTGCAGGACACG
CTCTTCGGCTTCGGGGCCGGCGTGATGCTGGCGGCCAGTTCCTTCTCGCTCATCATCCCGGGCCTGGAGGCCGCGAAAAC
CAACGGCGCCGGGTCATGGGCGGCCGGGGGCATCGTCGGCGCGTCCATCCTGCTGGGAGGGCTGGCGCTGCTCGCCATGG
AGCGCGTGCTGCCGCACGAGCATTTCATCAAGGGGGTGGAGGGCGGCCCCTCGCCGCGCACGCTGCGGCGCACCTGGCTG
TTCGTCTTCGCGATCGCGTTGCACAACCTGCCCGAGGGGCTGGCGATCGGCGTGGCCTACGGCGGCGCCAGCCCGCTGCA
GGCCGGCACGCTCACGGCCGGCATCGCCATCCAGGACGTGCCCGAGGGCCTGGTGGTGGCGATGGCGCTGCTCGCGGCGG
GCTACCGGCGCTGGCTGGCCGTGCTGCTGGGCATGGCCTCGGGCCTGGTGGAGCCGCTGGGCGCGGTGCTCGGCGCCTCG
GTCATCGGCCTGTCGGCCGGGCTGCTGCCCTGGGGCCTGGGCTTCGCTGCCGGGGCGATGCTGTTCGTCATCAGCCACGA
GATCATTCCCGAGTCGCATCGCAAGGGGCACGAGTCCTGGGCCACCGGCGGGCTCATGATCGGCTTCGTGCTGATGATGC
TGCTCGATACCGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
CGCCGGTACGCGAAGGCCCGCGGCTGACTCCGCCGACGTCCCCGCCCGTCCCCGAACGCCCGGGATCTTCATCGTGGAAA
ACCCGCCGGAGCCTCCGTCC

Downstream 100 bases:

>100_bases
CGTGTCCGCGCACGGATCGCCGCCCGCCGCTGCGGCTCATCCGTGCCGGATGGCCACGGTCTTGAGCGTGGTGAAGCCGT
GCAGCGCCTCCAGGCCCTTT

Product: zinc/iron permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPAQNTLSLRRPIWGPRRWLGLAIAVAGAVVLALQFTQFLQANPRVAQAWQGGLVAALATALGTLPVVFSQRLSERVQDT
LFGFGAGVMLAASSFSLIIPGLEAAKTNGAGSWAAGGIVGASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWL
FVFAIALHNLPEGLAIGVAYGGASPLQAGTLTAGIAIQDVPEGLVVAMALLAAGYRRWLAVLLGMASGLVEPLGAVLGAS
VIGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHESWATGGLMIGFVLMMLLDTALG

Sequences:

>Translated_300_residues
MPAQNTLSLRRPIWGPRRWLGLAIAVAGAVVLALQFTQFLQANPRVAQAWQGGLVAALATALGTLPVVFSQRLSERVQDT
LFGFGAGVMLAASSFSLIIPGLEAAKTNGAGSWAAGGIVGASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWL
FVFAIALHNLPEGLAIGVAYGGASPLQAGTLTAGIAIQDVPEGLVVAMALLAAGYRRWLAVLLGMASGLVEPLGAVLGAS
VIGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHESWATGGLMIGFVLMMLLDTALG
>Mature_299_residues
PAQNTLSLRRPIWGPRRWLGLAIAVAGAVVLALQFTQFLQANPRVAQAWQGGLVAALATALGTLPVVFSQRLSERVQDTL
FGFGAGVMLAASSFSLIIPGLEAAKTNGAGSWAAGGIVGASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWLF
VFAIALHNLPEGLAIGVAYGGASPLQAGTLTAGIAIQDVPEGLVVAMALLAAGYRRWLAVLLGMASGLVEPLGAVLGASV
IGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHESWATGGLMIGFVLMMLLDTALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=157, Percent_Identity=42.6751592356688, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI229577422, Length=157, Percent_Identity=42.6751592356688, Blast_Score=121, Evalue=6e-28,
Organism=Escherichia coli, GI1789419, Length=257, Percent_Identity=29.5719844357977, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507805, Length=301, Percent_Identity=32.890365448505, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24652846, Length=150, Percent_Identity=43.3333333333333, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 30930; Mature: 30799

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQNTLSLRRPIWGPRRWLGLAIAVAGAVVLALQFTQFLQANPRVAQAWQGGLVAALAT
CCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
ALGTLPVVFSQRLSERVQDTLFGFGAGVMLAASSFSLIIPGLEAAKTNGAGSWAAGGIVG
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEECCCHHHCCCCCCCCHHHHHHH
ASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWLFVFAIALHNLPEGLAIGVAY
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GGASPLQAGTLTAGIAIQDVPEGLVVAMALLAAGYRRWLAVLLGMASGLVEPLGAVLGAS
CCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHESWATGGLMIGFVLMMLLDTALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAQNTLSLRRPIWGPRRWLGLAIAVAGAVVLALQFTQFLQANPRVAQAWQGGLVAALAT
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHH
ALGTLPVVFSQRLSERVQDTLFGFGAGVMLAASSFSLIIPGLEAAKTNGAGSWAAGGIVG
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCEEECCCHHHCCCCCCCCHHHHHHH
ASILLGGLALLAMERVLPHEHFIKGVEGGPSPRTLRRTWLFVFAIALHNLPEGLAIGVAY
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GGASPLQAGTLTAGIAIQDVPEGLVVAMALLAAGYRRWLAVLLGMASGLVEPLGAVLGAS
CCCCCCCCCHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGLSAGLLPWGLGFAAGAMLFVISHEIIPESHRKGHESWATGGLMIGFVLMMLLDTALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]