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The map label for this gene is pheC [H]

Identifier: 120611141

GI number: 120611141

Start: 2702424

End: 2703206

Strand: Direct

Name: pheC [H]

Synonym: Aave_2470

Alternate gene names: 120611141

Gene position: 2702424-2703206 (Clockwise)

Preceding gene: 120611140

Following gene: 120611145

Centisome position: 50.49

GC content: 67.82

Gene sequence:

>783_bases
ATGCAGCGCACGTCCGCCGCCACCCTCATCGCCACCGCCGCCCTGGCGGCCGCCGGCTTCCTGCAGGCCGCCCATGCCGG
GCCCCGGCTCGACCGGATCATGGACACCAAGGTGCTGCGCGTCGGCACGCCCGGCGACTACCGGCCCTTCGCCATCAAGG
CCGATGGCGGCTATGCCGGCCACGACATCGATGTGGTCGAGGCCATGGCGAAGGAACTGGGCGTGAAGATCGAATACGTG
CCCACGAGCTGGCCCAACCTGATGAAGGACATCCAGGCCGACAGGTTCGACGTGGCCGTGGGCGGCATCACGCGCAATGT
CACGCGCATCCGCCAGATCGAAATGCTGCCGGGCTACGCGCCGTTCGGCAAGGTGGCGCTGGTGCGGGCCTCCGACAAGG
ACAGGTTCCGGGCCCTGGCCGATCTGAACCGGCCGGGCGTGCGCGTCATCAAGAACCCGGGCGGCACCAACGAAACCTTC
GTGCTGGAGAACCTCAAGGCGGCCGATGTCAGCACGCACGACAAGAACGCCGAGATCCCCGCGCTCATCGCCGAGGGCAA
GGGCGACGTGATGATCACCGAGACGTACGAGGCCCTGCACTACGCCAAGGCCGACCCGCGCCTCCATGCGGCTTTCGTCG
CCGCGCCGCTCACGCCGCAGAACACCCTGGGATTCATGCTGCCCAAGGACGACGCGGACTATTCGCGCGTGATGGAGTTC
GTCTGGGGCCTGATGGAAGCCCGCGGCCAGCTCAAGCAGGCGGCCGACAAGTGGCTCAAGTGA

Upstream 100 bases:

>100_bases
GGCGCGGCCGTGGCCGGGCGGAGTCCCTGCGGATCTCCGGAGCGCGGCATTTGTCCGGGACCGCCATCCCTTTTGCAACG
AACCCTCGAAGGCCCCTCGC

Downstream 100 bases:

>100_bases
ACGTGCGGGCGGGTCTGCCGGCCTGAGCCGTTCAGCCTGCCATCCACTGCGCCGTGCGTACGGCCAGTGCGGCGGCATCG
GGCCGGGCGGCCGGGTCTTC

Product: cyclohexadienyl dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MQRTSAATLIATAALAAAGFLQAAHAGPRLDRIMDTKVLRVGTPGDYRPFAIKADGGYAGHDIDVVEAMAKELGVKIEYV
PTSWPNLMKDIQADRFDVAVGGITRNVTRIRQIEMLPGYAPFGKVALVRASDKDRFRALADLNRPGVRVIKNPGGTNETF
VLENLKAADVSTHDKNAEIPALIAEGKGDVMITETYEALHYAKADPRLHAAFVAAPLTPQNTLGFMLPKDDADYSRVMEF
VWGLMEARGQLKQAADKWLK

Sequences:

>Translated_260_residues
MQRTSAATLIATAALAAAGFLQAAHAGPRLDRIMDTKVLRVGTPGDYRPFAIKADGGYAGHDIDVVEAMAKELGVKIEYV
PTSWPNLMKDIQADRFDVAVGGITRNVTRIRQIEMLPGYAPFGKVALVRASDKDRFRALADLNRPGVRVIKNPGGTNETF
VLENLKAADVSTHDKNAEIPALIAEGKGDVMITETYEALHYAKADPRLHAAFVAAPLTPQNTLGFMLPKDDADYSRVMEF
VWGLMEARGQLKQAADKWLK
>Mature_260_residues
MQRTSAATLIATAALAAAGFLQAAHAGPRLDRIMDTKVLRVGTPGDYRPFAIKADGGYAGHDIDVVEAMAKELGVKIEYV
PTSWPNLMKDIQADRFDVAVGGITRNVTRIRQIEMLPGYAPFGKVALVRASDKDRFRALADLNRPGVRVIKNPGGTNETF
VLENLKAADVSTHDKNAEIPALIAEGKGDVMITETYEALHYAKADPRLHAAFVAAPLTPQNTLGFMLPKDDADYSRVMEF
VWGLMEARGQLKQAADKWLK

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=260, Percent_Identity=23.8461538461538, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787031, Length=250, Percent_Identity=24, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28346; Mature: 28346

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRTSAATLIATAALAAAGFLQAAHAGPRLDRIMDTKVLRVGTPGDYRPFAIKADGGYAG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCEEEEECCCCCC
HDIDVVEAMAKELGVKIEYVPTSWPNLMKDIQADRFDVAVGGITRNVTRIRQIEMLPGYA
CCHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCC
PFGKVALVRASDKDRFRALADLNRPGVRVIKNPGGTNETFVLENLKAADVSTHDKNAEIP
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCC
ALIAEGKGDVMITETYEALHYAKADPRLHAAFVAAPLTPQNTLGFMLPKDDADYSRVMEF
EEEECCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHH
VWGLMEARGQLKQAADKWLK
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQRTSAATLIATAALAAAGFLQAAHAGPRLDRIMDTKVLRVGTPGDYRPFAIKADGGYAG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCEEEEECCCCCCCCEEEEECCCCCC
HDIDVVEAMAKELGVKIEYVPTSWPNLMKDIQADRFDVAVGGITRNVTRIRQIEMLPGYA
CCHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCC
PFGKVALVRASDKDRFRALADLNRPGVRVIKNPGGTNETFVLENLKAADVSTHDKNAEIP
CCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCC
ALIAEGKGDVMITETYEALHYAKADPRLHAAFVAAPLTPQNTLGFMLPKDDADYSRVMEF
EEEECCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHH
VWGLMEARGQLKQAADKWLK
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]