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The map label for this gene is rpiA [H]

Identifier: 120611127

GI number: 120611127

Start: 2678701

End: 2679393

Strand: Direct

Name: rpiA [H]

Synonym: Aave_2456

Alternate gene names: 120611127

Gene position: 2678701-2679393 (Clockwise)

Preceding gene: 120611125

Following gene: 120611133

Centisome position: 50.04

GC content: 67.24

Gene sequence:

>693_bases
ATGACCACTCCCGCACCCCTTTCCCAAGATGAACTCAAAGCCCTGGTGGGCCAGGCCGCGCTGAAATACGTGGTGCCCGG
CGACATCGTCGGCGTCGGCACGGGCTCGACGGTGAACCAGTTCATCCAGGCACTGGGTTCGATGAAGGACCGCATCCGGG
GCGCGGTGTCGAGTTCCGAGGCCAGCACGCAGCGGCTGCGTGCGCTGGGCATTCCGGTCTTCGACGCCAACGAGGTGGAG
TCCCTGTCCGTCTATATCGATGGCGCGGACGAGATCGATCCGCGAGGCCACATGGTCAAGGGCGGTGGCGCTGCACTCAC
GCGCGAGAAGATCGTGGCGGCCCTGGCCCGGCAGTTCGTATGCATCGCCGACGTCTCCAAGCTGGTGGAGACGCTGGGCC
GGTTTCCGCTTCCGGTCGAGGTGATTCCCATGGCGGCGCAGCAGATCGCGCGCCGGTTCGCCACGCGGGGCGGGCAGGCG
GTGTTGCGCCGGGGGGCGGACGGACAGCCGCTGGTCACGGACAACCAGCAGTACATCCTCGACGTGAAGGGCCTCTCGAT
CCAGGATCCGCTGGCGTTCGAGTCGGAGGTCAGCCAGTGGCCGGGCGTGGTGACGGTGGGCGTCTTCGCCCATCAGAAGG
CCGACGTGGCGCTGATCGGTGCGCCGGAGGGTGTCCGGACTTTCACGTACTGA

Upstream 100 bases:

>100_bases
GTGGGCAGCTTCGGCATCCATGCCGAAGAGGAAGGGGCGGGTGAGGGCGTAGGGGATCAGGGACATGGGGATAATTCGGG
CTTCACTCCGATTCTCTCCC

Downstream 100 bases:

>100_bases
GAGGGGGGCAGCCGGCGCGCCCGGCCCGCGGCCGTTGCGCACCGTTACCCATGCACGTCAGAACTGGATGCCGGCGGGGT
TCGCAGGCGAAGGCGCAGGC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTTPAPLSQDELKALVGQAALKYVVPGDIVGVGTGSTVNQFIQALGSMKDRIRGAVSSSEASTQRLRALGIPVFDANEVE
SLSVYIDGADEIDPRGHMVKGGGAALTREKIVAALARQFVCIADVSKLVETLGRFPLPVEVIPMAAQQIARRFATRGGQA
VLRRGADGQPLVTDNQQYILDVKGLSIQDPLAFESEVSQWPGVVTVGVFAHQKADVALIGAPEGVRTFTY

Sequences:

>Translated_230_residues
MTTPAPLSQDELKALVGQAALKYVVPGDIVGVGTGSTVNQFIQALGSMKDRIRGAVSSSEASTQRLRALGIPVFDANEVE
SLSVYIDGADEIDPRGHMVKGGGAALTREKIVAALARQFVCIADVSKLVETLGRFPLPVEVIPMAAQQIARRFATRGGQA
VLRRGADGQPLVTDNQQYILDVKGLSIQDPLAFESEVSQWPGVVTVGVFAHQKADVALIGAPEGVRTFTY
>Mature_229_residues
TTPAPLSQDELKALVGQAALKYVVPGDIVGVGTGSTVNQFIQALGSMKDRIRGAVSSSEASTQRLRALGIPVFDANEVES
LSVYIDGADEIDPRGHMVKGGGAALTREKIVAALARQFVCIADVSKLVETLGRFPLPVEVIPMAAQQIARRFATRGGQAV
LRRGADGQPLVTDNQQYILDVKGLSIQDPLAFESEVSQWPGVVTVGVFAHQKADVALIGAPEGVRTFTY

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=222, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=9e-24,
Organism=Escherichia coli, GI1789280, Length=222, Percent_Identity=60.8108108108108, Blast_Score=271, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17551758, Length=218, Percent_Identity=38.9908256880734, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6324669, Length=212, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281364072, Length=197, Percent_Identity=33.502538071066, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24369; Mature: 24238

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPAPLSQDELKALVGQAALKYVVPGDIVGVGTGSTVNQFIQALGSMKDRIRGAVSSSE
CCCCCCCCHHHHHHHHHHHHHHEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCH
ASTQRLRALGIPVFDANEVESLSVYIDGADEIDPRGHMVKGGGAALTREKIVAALARQFV
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHH
CIADVSKLVETLGRFPLPVEVIPMAAQQIARRFATRGGQAVLRRGADGQPLVTDNQQYIL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEECCCEEEE
DVKGLSIQDPLAFESEVSQWPGVVTVGVFAHQKADVALIGAPEGVRTFTY
EECCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TTPAPLSQDELKALVGQAALKYVVPGDIVGVGTGSTVNQFIQALGSMKDRIRGAVSSSE
CCCCCCCHHHHHHHHHHHHHHEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCH
ASTQRLRALGIPVFDANEVESLSVYIDGADEIDPRGHMVKGGGAALTREKIVAALARQFV
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHH
CIADVSKLVETLGRFPLPVEVIPMAAQQIARRFATRGGQAVLRRGADGQPLVTDNQQYIL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEECCCEEEE
DVKGLSIQDPLAFESEVSQWPGVVTVGVFAHQKADVALIGAPEGVRTFTY
EECCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA