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The map label for this gene is iscR [H]

Identifier: 120611113

GI number: 120611113

Start: 2667321

End: 2667857

Strand: Direct

Name: iscR [H]

Synonym: Aave_2442

Alternate gene names: 120611113

Gene position: 2667321-2667857 (Clockwise)

Preceding gene: 120611112

Following gene: 120611114

Centisome position: 49.83

GC content: 65.36

Gene sequence:

>537_bases
ATGCGTCTCACTACCAAAGGCCGTTTCGCGGTCACCGCAATGATCGACCTGGCCCTCCGCCAGAACAATGGTCCCGTCAC
GCTGGCGGCCATCAGCCAGCGCCAGCAGATTTCGCTGTCGTACCTGGAGCAGCTCTTCGGCAAGCTGCGCCGCCATGAAC
TCGTCGAATCCACCCGCGGCCCGGGCGGCGGCTACACCCTGGCCCGCAAGGCGGCCGACATCACCGTCGCCGACATCATC
GTGTCGGTGGACGAACCCATCGACGCCACGCAATGCGGCGGCAAGGAAAACTGCCTGGGCGAGGCGGGCCGCTGCATGAC
GCACGAGCTGTGGGCCTCCCTGAACCAGCGCATGGTCGAGTTCCTGGACTCCGTCACGCTGCAGAAGCTGGTGGACGACC
AGATCGCCAAGGGCGTGCAGATCGAGGACAAGCCGGTGGTCCGCCGCGCCATTTCCACGACGCCGGTGGTCAAGCCCATC
CGCGTGAATGCACCCAACTCCGTGTTCGCCCTGGGCAACGCATTCGCCAAATCCTGA

Upstream 100 bases:

>100_bases
GGAGTGTAGGGGCGGAGACGAGCCGGCGACCTCTGCGGTATGCCCAGTGCCATCGGGTTCCGGCATTTCTATAACGGACA
AGCTAGCAAAGGAGCTTGCG

Downstream 100 bases:

>100_bases
ACCCGACGGCCCGGGCGACCCCGGGGTTCGGGGTCGGCTCGGTCAGGGCCGCTCCCGTCGCCACGATTCGCCAGCCAGAC
ATTTACTGAGCCAGCCATGG

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRLTTKGRFAVTAMIDLALRQNNGPVTLAAISQRQQISLSYLEQLFGKLRRHELVESTRGPGGGYTLARKAADITVADII
VSVDEPIDATQCGGKENCLGEAGRCMTHELWASLNQRMVEFLDSVTLQKLVDDQIAKGVQIEDKPVVRRAISTTPVVKPI
RVNAPNSVFALGNAFAKS

Sequences:

>Translated_178_residues
MRLTTKGRFAVTAMIDLALRQNNGPVTLAAISQRQQISLSYLEQLFGKLRRHELVESTRGPGGGYTLARKAADITVADII
VSVDEPIDATQCGGKENCLGEAGRCMTHELWASLNQRMVEFLDSVTLQKLVDDQIAKGVQIEDKPVVRRAISTTPVVKPI
RVNAPNSVFALGNAFAKS
>Mature_178_residues
MRLTTKGRFAVTAMIDLALRQNNGPVTLAAISQRQQISLSYLEQLFGKLRRHELVESTRGPGGGYTLARKAADITVADII
VSVDEPIDATQCGGKENCLGEAGRCMTHELWASLNQRMVEFLDSVTLQKLVDDQIAKGVQIEDKPVVRRAISTTPVVKPI
RVNAPNSVFALGNAFAKS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=53.7313432835821, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 19377; Mature: 19377

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLALRQNNGPVTLAAISQRQQISLSYLEQLFGKLRRHELVESTRG
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PGGGYTLARKAADITVADIIVSVDEPIDATQCGGKENCLGEAGRCMTHELWASLNQRMVE
CCCCCHHHHHHCCHHHHHHEEECCCCCCHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHH
FLDSVTLQKLVDDQIAKGVQIEDKPVVRRAISTTPVVKPIRVNAPNSVFALGNAFAKS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCEEECCHHHHCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLALRQNNGPVTLAAISQRQQISLSYLEQLFGKLRRHELVESTRG
CCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PGGGYTLARKAADITVADIIVSVDEPIDATQCGGKENCLGEAGRCMTHELWASLNQRMVE
CCCCCHHHHHHCCHHHHHHEEECCCCCCHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHH
FLDSVTLQKLVDDQIAKGVQIEDKPVVRRAISTTPVVKPIRVNAPNSVFALGNAFAKS
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCEEEECCCCCEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA