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The map label for this gene is yfjP [H]

Identifier: 120610993

GI number: 120610993

Start: 2549718

End: 2550377

Strand: Direct

Name: yfjP [H]

Synonym: Aave_2321

Alternate gene names: 120610993

Gene position: 2549718-2550377 (Clockwise)

Preceding gene: 120610992

Following gene: 120610994

Centisome position: 47.63

GC content: 69.85

Gene sequence:

>660_bases
GTGGCCCCCAGCAAGAAAACAGCGGGGACGGCCGAGCCGTCCACCGCCCCGGGCTACTGGGCGGACGCCTGCCGCCACCT
GGTCAAGAAGGACCGCGTCATGAAGCGGCTGATCCCGCAGCTCGGCGACGTGGCCCTCGTGGCCCGCGGCGACGCCTTCA
CCACGCTGGCGCGCAGCATCGTGGGGCAGCAGGTCTCGGTCGCGTCCGCGCAGAAGGTCTGGGACAGGTTCGCCGCGCTG
CCCCGCAGCATGACGCCGGCCGCCGTGCTCAAGCTCAAGGTGGACGACATGCGCGCCGCGGGCCTGTCCGCCCGCAAGGT
GGACTACCTGGTGGACCTGGCGCTGCATTTCGACACCGGCCGCCTGCACGTCAAGGACTGGGATGCGATGGACGACGAAG
CCATCGCGGCCGAGCTGGTCGCCATCCGCGGCATCGGCCGGTGGACGGCCGACATGTTCCTGATCTTCCACCTGGCGCGG
CCCAACGTGCTGCCCCTGGACGACGCTACCCTGCTGCAGGGCATCAGCCAGCACTATTTCTCGGGCGACCCGGTCAGCCG
CAGCGATGCCCGCGAGGTCGCCGAGGCCTGGAAACCCTGGTGCAGCGTGGCGAGTTGGTATATTTGGCGGTCGCTCGCCC
CCCTGCCGGTGGACTATTGA

Upstream 100 bases:

>100_bases
AGGACTCCCCCGCGGGCACGACCTGGGAGGCCGCGCAGTGAGCCCGGGCCGCCCCTTCCGTTTCCCGCACCGCCGGTCTC
CCCTCCAGACAAGGTAAGCC

Downstream 100 bases:

>100_bases
CCGTCCGCCAGGACACTGCGTGCCGCGCGTTCCGCGCGCGCCGAGGCTACAGCCCAAGGAGAAAACAATTGGCGAAAAAG
ACTTTTCTGGACTTCGAGCA

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAPSKKTAGTAEPSTAPGYWADACRHLVKKDRVMKRLIPQLGDVALVARGDAFTTLARSIVGQQVSVASAQKVWDRFAAL
PRSMTPAAVLKLKVDDMRAAGLSARKVDYLVDLALHFDTGRLHVKDWDAMDDEAIAAELVAIRGIGRWTADMFLIFHLAR
PNVLPLDDATLLQGISQHYFSGDPVSRSDAREVAEAWKPWCSVASWYIWRSLAPLPVDY

Sequences:

>Translated_219_residues
MAPSKKTAGTAEPSTAPGYWADACRHLVKKDRVMKRLIPQLGDVALVARGDAFTTLARSIVGQQVSVASAQKVWDRFAAL
PRSMTPAAVLKLKVDDMRAAGLSARKVDYLVDLALHFDTGRLHVKDWDAMDDEAIAAELVAIRGIGRWTADMFLIFHLAR
PNVLPLDDATLLQGISQHYFSGDPVSRSDAREVAEAWKPWCSVASWYIWRSLAPLPVDY
>Mature_218_residues
APSKKTAGTAEPSTAPGYWADACRHLVKKDRVMKRLIPQLGDVALVARGDAFTTLARSIVGQQVSVASAQKVWDRFAALP
RSMTPAAVLKLKVDDMRAAGLSARKVDYLVDLALHFDTGRLHVKDWDAMDDEAIAAELVAIRGIGRWTADMFLIFHLARP
NVLPLDDATLLQGISQHYFSGDPVSRSDAREVAEAWKPWCSVASWYIWRSLAPLPVDY

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 24171; Mature: 24040

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSKKTAGTAEPSTAPGYWADACRHLVKKDRVMKRLIPQLGDVALVARGDAFTTLARSI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHH
VGQQVSVASAQKVWDRFAALPRSMTPAAVLKLKVDDMRAAGLSARKVDYLVDLALHFDTG
HCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHHHHCCCCHHHHHHHHHHHHEECCC
RLHVKDWDAMDDEAIAAELVAIRGIGRWTADMFLIFHLARPNVLPLDDATLLQGISQHYF
EEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
SGDPVSRSDAREVAEAWKPWCSVASWYIWRSLAPLPVDY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
APSKKTAGTAEPSTAPGYWADACRHLVKKDRVMKRLIPQLGDVALVARGDAFTTLARSI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHH
VGQQVSVASAQKVWDRFAALPRSMTPAAVLKLKVDDMRAAGLSARKVDYLVDLALHFDTG
HCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHHHHCCCCHHHHHHHHHHHHEECCC
RLHVKDWDAMDDEAIAAELVAIRGIGRWTADMFLIFHLARPNVLPLDDATLLQGISQHYF
EEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHC
SGDPVSRSDAREVAEAWKPWCSVASWYIWRSLAPLPVDY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]