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The map label for this gene is accA [H]

Identifier: 120610994

GI number: 120610994

Start: 2550446

End: 2551420

Strand: Direct

Name: accA [H]

Synonym: Aave_2322

Alternate gene names: 120610994

Gene position: 2550446-2551420 (Clockwise)

Preceding gene: 120610993

Following gene: 120610995

Centisome position: 47.65

GC content: 66.05

Gene sequence:

>975_bases
TTGGCGAAAAAGACTTTTCTGGACTTCGAGCAGCCCATCGCCGAGCTGGAATCGAAGATCGAGGAACTGCGCTACGTGCA
GACCGAAAGCGCGGTGGACATTTCCGAGGAAATCGACCAGCTCAGCCGCAAGAGCCAGCAGCTCACCAAGGACATCTACA
GCGAGCTGACGCCCTGGCAGATCACGAAGATCGCCCGCCACCCCGAGCGGCCCTACACCCTCGACTACGTGCGCGAGATC
TTCACCGATTTCGTCGAGATGCACGGTGACCGGCACTTCGCCGACGACCTCTCCATCATCGGCGGCCTCGCGCGCTTCAA
CGGCCATGCCTGCATGGTGATCGGCCACCAGAAGGGACGCGACACCAAGGAGCGTGCCGCGCGCAACTTCGGCATGAGCC
GCCCCGAGGGCTACCGCAAGGCCCTGCGCCTCATGAAAACGGCCGAGAAGTTCCGCCTGCCCGTGTTCACCTTCGTGGAC
ACGCCGGGCGCCTACCCCGGCATCGACGCCGAGGAGCGCGGCCAGTCCGAGGCCATCGGCCGCAACATCTTCGAGATGGC
GCAGCTGGAAGTGCCCATCATCACCACGGTGATCGGCGAGGGCGGCTCCGGCGGCGCGCTGGCCATCAGCGTCGCCGACC
AGGTCGTGATGCTGCAGTATTCGATCTATTCGGTCATCAGCCCCGAGGGCTGCGCCTCCATCCTCTGGAAGACCGGCGAC
AAGGCCCAGGACGCGGCCGATGCCATGGGCATCACCGCGCACCGCCTCAAGGCCCTGGGCCTGGTGGACAAGATCGTGAG
CGAGCCCGTGGGCGGCGCCCACCGCGACCACAAGCAGATGGCCGCCTTCCTCAAGCGCGCGCTGGGCGACGCCCACCGCC
AGCTGGCGGACCTCAAGCCGCGCGAACTGCTGGACCGCCGCTACGAGCGGCTTCAGAGCTACGGCCGGTTCAACGATACC
CGCGCAGAAAGGTGA

Upstream 100 bases:

>100_bases
GGTCGCTCGCCCCCCTGCCGGTGGACTATTGACCGTCCGCCAGGACACTGCGTGCCGCGCGTTCCGCGCGCGCCGAGGCT
ACAGCCCAAGGAGAAAACAA

Downstream 100 bases:

>100_bases
AGCACCCCCCCGAGGCCCTGCGGGCCTTCCCCCCGCTCTCGCCGTGCTGCGCACGGCGGGCAGGAGGACGACGCCGGTGG
CCCGGCGGAGCCGGTTCCAC

Product: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAKKTFLDFEQPIAELESKIEELRYVQTESAVDISEEIDQLSRKSQQLTKDIYSELTPWQITKIARHPERPYTLDYVREI
FTDFVEMHGDRHFADDLSIIGGLARFNGHACMVIGHQKGRDTKERAARNFGMSRPEGYRKALRLMKTAEKFRLPVFTFVD
TPGAYPGIDAEERGQSEAIGRNIFEMAQLEVPIITTVIGEGGSGGALAISVADQVVMLQYSIYSVISPEGCASILWKTGD
KAQDAADAMGITAHRLKALGLVDKIVSEPVGGAHRDHKQMAAFLKRALGDAHRQLADLKPRELLDRRYERLQSYGRFNDT
RAER

Sequences:

>Translated_324_residues
MAKKTFLDFEQPIAELESKIEELRYVQTESAVDISEEIDQLSRKSQQLTKDIYSELTPWQITKIARHPERPYTLDYVREI
FTDFVEMHGDRHFADDLSIIGGLARFNGHACMVIGHQKGRDTKERAARNFGMSRPEGYRKALRLMKTAEKFRLPVFTFVD
TPGAYPGIDAEERGQSEAIGRNIFEMAQLEVPIITTVIGEGGSGGALAISVADQVVMLQYSIYSVISPEGCASILWKTGD
KAQDAADAMGITAHRLKALGLVDKIVSEPVGGAHRDHKQMAAFLKRALGDAHRQLADLKPRELLDRRYERLQSYGRFNDT
RAER
>Mature_323_residues
AKKTFLDFEQPIAELESKIEELRYVQTESAVDISEEIDQLSRKSQQLTKDIYSELTPWQITKIARHPERPYTLDYVREIF
TDFVEMHGDRHFADDLSIIGGLARFNGHACMVIGHQKGRDTKERAARNFGMSRPEGYRKALRLMKTAEKFRLPVFTFVDT
PGAYPGIDAEERGQSEAIGRNIFEMAQLEVPIITTVIGEGGSGGALAISVADQVVMLQYSIYSVISPEGCASILWKTGDK
AQDAADAMGITAHRLKALGLVDKIVSEPVGGAHRDHKQMAAFLKRALGDAHRQLADLKPRELLDRRYERLQSYGRFNDTR
AER

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=314, Percent_Identity=61.4649681528662, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 36444; Mature: 36313

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKTFLDFEQPIAELESKIEELRYVQTESAVDISEEIDQLSRKSQQLTKDIYSELTPWQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITKIARHPERPYTLDYVREIFTDFVEMHGDRHFADDLSIIGGLARFNGHACMVIGHQKGR
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCC
DTKERAARNFGMSRPEGYRKALRLMKTAEKFRLPVFTFVDTPGAYPGIDAEERGQSEAIG
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCHHHHH
RNIFEMAQLEVPIITTVIGEGGSGGALAISVADQVVMLQYSIYSVISPEGCASILWKTGD
HHHHHHHHHCCCHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
KAQDAADAMGITAHRLKALGLVDKIVSEPVGGAHRDHKQMAAFLKRALGDAHRQLADLKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
RELLDRRYERLQSYGRFNDTRAER
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AKKTFLDFEQPIAELESKIEELRYVQTESAVDISEEIDQLSRKSQQLTKDIYSELTPWQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ITKIARHPERPYTLDYVREIFTDFVEMHGDRHFADDLSIIGGLARFNGHACMVIGHQKGR
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCC
DTKERAARNFGMSRPEGYRKALRLMKTAEKFRLPVFTFVDTPGAYPGIDAEERGQSEAIG
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCHHHHH
RNIFEMAQLEVPIITTVIGEGGSGGALAISVADQVVMLQYSIYSVISPEGCASILWKTGD
HHHHHHHHHCCCHHEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHCCCC
KAQDAADAMGITAHRLKALGLVDKIVSEPVGGAHRDHKQMAAFLKRALGDAHRQLADLKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCH
RELLDRRYERLQSYGRFNDTRAER
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA