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The map label for this gene is glcD [H]

Identifier: 120610139

GI number: 120610139

Start: 1598563

End: 1600005

Strand: Reverse

Name: glcD [H]

Synonym: Aave_1452

Alternate gene names: 120610139

Gene position: 1600005-1598563 (Counterclockwise)

Preceding gene: 120610140

Following gene: 120610137

Centisome position: 29.89

GC content: 68.81

Gene sequence:

>1443_bases
ATGACCGCCTCCCTGATCGACACCCTGCGCCAGATCGTCGGCGCCAACCATGTCCTGGCCGATGGCGACCTCACTGCCTG
GGAGCAGGACTGGCGCCGGCGAGCCCGCGGCAAGGCCCTGGCCGTGGTCCGCCCCGCCAGCACCGCCGAGGTGGCTGCCG
TGGTGAAAGCCTGCGCCGCCCACGGCACGGCGCTGGTGCCCCAGGGCGGCAATACCGGCCTGGCGGTGGGCTCCATCCCC
GATGCATCGGGCACGCAGGTGGTGCTGAGCCTCACGCGCATGAATGCAGTGCGCAACGTCGATGCCGACAACCTCACCAT
GACGGTGGAGGCCGGCTGCATCCTGCAGAATCTGCAGGACACGGCCGAAAAGGCCGGGCTGCTCTTCCCGCTCAGCCTGG
CGGCCGAAGGCAGTTGCACCATCGGGGGCAACCTCGCCACCAACGCCGGCGGAACGCAGGTGGTGCGCTACGGCAACACG
CGCGACCTGTGCCTGGGGCTGGAAGTGGTCACGCCGCAGGGCGAGGTCTGGAGCGGGCTGAAGGGCCTGCGCAAGGACAA
CACCGGCTACGACCTGCGCGACCTGTTCATCGGCAGCGAGGGCACGCTGGGCATCATCACCGCCGCCACCATGAAGCTCT
ACCCCCGTCCGGCAGCCAGCCTCACTGCCTGGGCCGCGGTACCGTCCATGGCGCACGCGGTGCAGCTGCTCGCACTGGCC
CACGGCCACCTGGGTGCCAGCCTGACGGGCTTCGAGGTCATGGGCCGCTTCGCGCTCAGCCTCGTGAACAAACACATGCC
GCAGTTGCGCGTGCCCTTCATCGACCAGGAGGAAGTGCCCTACGGCGTGCTGCTGGAAAACAGCGACAGTGAATCCGAGG
AGCACGCCCGCGCCCGCTTCGAAGCGCTGCTGGAGACCGCCTTCGAGGCCGGCTGCGTGGTGGACGCCGTGGTGGCGGAG
AACCTCGCCCAGGCGCACCAGCTGTGGCACATCCGCGAGAACATTCCGCTCGCCCAGGCCGAGGAAGGGCTGAACATCAA
GCACGACATCTCCGTGCCCATCTCGCGCATCCCGGCCTTCGTGGAGCATGCGGACGCGCTGCTGCAGCGCGAGATCCCGG
GCGTGCGCCTGGTCAATTTCGGCCACCTGGGGGACGGCAACCTGCACTACAACGTGCAGGCGCCTGCGGAGGGCGATGCC
AAGGCCTTCCTGCGCGACCAGGAAGACCGCGTGAACCATCTCGTTTACGAGGCCGTGGCCGCGTTCGGCGGCTCGTTCTC
CGCCGAGCACGGCGTGGGCGCGCTCAAGGTGGACAAGCTGCAGCAGTACCAGTCCCCCGTGGCGCTGGCGATGATGCGAG
CCATCAAGGGAGCGCTCGACCCCCAGGGCCTGATGAACCCGCAATGCATGTTGCCGGTGCGGGCGGACCAGGCCATCAGC
TGA

Upstream 100 bases:

>100_bases
GCCCGCACGGCGCGGTCGCATCCCGCCACGCCCCCATGACCCCGGTCCGCCGCTGCCGTCCTGCGTTCCTCTCCCGTTTC
GTTGTCACGAGAAGATTTCC

Downstream 100 bases:

>100_bases
TGGCAGCGGTTCAGCGCCGCGCGTTCTCCATCATCGTGCGCACTTCGGCCGGCATCTGCACGCCGCGGCCATAGTCCTGC
ACGTCCCACTCCTCATCGCC

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTASLIDTLRQIVGANHVLADGDLTAWEQDWRRRARGKALAVVRPASTAEVAAVVKACAAHGTALVPQGGNTGLAVGSIP
DASGTQVVLSLTRMNAVRNVDADNLTMTVEAGCILQNLQDTAEKAGLLFPLSLAAEGSCTIGGNLATNAGGTQVVRYGNT
RDLCLGLEVVTPQGEVWSGLKGLRKDNTGYDLRDLFIGSEGTLGIITAATMKLYPRPAASLTAWAAVPSMAHAVQLLALA
HGHLGASLTGFEVMGRFALSLVNKHMPQLRVPFIDQEEVPYGVLLENSDSESEEHARARFEALLETAFEAGCVVDAVVAE
NLAQAHQLWHIRENIPLAQAEEGLNIKHDISVPISRIPAFVEHADALLQREIPGVRLVNFGHLGDGNLHYNVQAPAEGDA
KAFLRDQEDRVNHLVYEAVAAFGGSFSAEHGVGALKVDKLQQYQSPVALAMMRAIKGALDPQGLMNPQCMLPVRADQAIS

Sequences:

>Translated_480_residues
MTASLIDTLRQIVGANHVLADGDLTAWEQDWRRRARGKALAVVRPASTAEVAAVVKACAAHGTALVPQGGNTGLAVGSIP
DASGTQVVLSLTRMNAVRNVDADNLTMTVEAGCILQNLQDTAEKAGLLFPLSLAAEGSCTIGGNLATNAGGTQVVRYGNT
RDLCLGLEVVTPQGEVWSGLKGLRKDNTGYDLRDLFIGSEGTLGIITAATMKLYPRPAASLTAWAAVPSMAHAVQLLALA
HGHLGASLTGFEVMGRFALSLVNKHMPQLRVPFIDQEEVPYGVLLENSDSESEEHARARFEALLETAFEAGCVVDAVVAE
NLAQAHQLWHIRENIPLAQAEEGLNIKHDISVPISRIPAFVEHADALLQREIPGVRLVNFGHLGDGNLHYNVQAPAEGDA
KAFLRDQEDRVNHLVYEAVAAFGGSFSAEHGVGALKVDKLQQYQSPVALAMMRAIKGALDPQGLMNPQCMLPVRADQAIS
>Mature_479_residues
TASLIDTLRQIVGANHVLADGDLTAWEQDWRRRARGKALAVVRPASTAEVAAVVKACAAHGTALVPQGGNTGLAVGSIPD
ASGTQVVLSLTRMNAVRNVDADNLTMTVEAGCILQNLQDTAEKAGLLFPLSLAAEGSCTIGGNLATNAGGTQVVRYGNTR
DLCLGLEVVTPQGEVWSGLKGLRKDNTGYDLRDLFIGSEGTLGIITAATMKLYPRPAASLTAWAAVPSMAHAVQLLALAH
GHLGASLTGFEVMGRFALSLVNKHMPQLRVPFIDQEEVPYGVLLENSDSESEEHARARFEALLETAFEAGCVVDAVVAEN
LAQAHQLWHIRENIPLAQAEEGLNIKHDISVPISRIPAFVEHADALLQREIPGVRLVNFGHLGDGNLHYNVQAPAEGDAK
AFLRDQEDRVNHLVYEAVAAFGGSFSAEHGVGALKVDKLQQYQSPVALAMMRAIKGALDPQGLMNPQCMLPVRADQAIS

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=452, Percent_Identity=40.4867256637168, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI37595756, Length=495, Percent_Identity=29.2929292929293, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI37595754, Length=518, Percent_Identity=28.3783783783784, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4501993, Length=198, Percent_Identity=32.8282828282828, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1789351, Length=482, Percent_Identity=28.2157676348548, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI48994907, Length=221, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994914, Length=161, Percent_Identity=32.2981366459627, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=465, Percent_Identity=34.1935483870968, Blast_Score=272, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI71992373, Length=456, Percent_Identity=27.6315789473684, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71992381, Length=456, Percent_Identity=26.5350877192982, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992392, Length=380, Percent_Identity=28.9473684210526, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=198, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320023, Length=477, Percent_Identity=35.6394129979036, Blast_Score=313, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6320764, Length=469, Percent_Identity=33.0490405117271, Blast_Score=273, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6320027, Length=483, Percent_Identity=26.2939958592132, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI18921117, Length=465, Percent_Identity=38.494623655914, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24639277, Length=465, Percent_Identity=38.494623655914, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24639275, Length=465, Percent_Identity=38.494623655914, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI24653753, Length=209, Percent_Identity=30.1435406698565, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51034; Mature: 50903

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASLIDTLRQIVGANHVLADGDLTAWEQDWRRRARGKALAVVRPASTAEVAAVVKACAA
CCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
HGTALVPQGGNTGLAVGSIPDASGTQVVLSLTRMNAVRNVDADNLTMTVEAGCILQNLQD
CCCEEEECCCCCCEEECCCCCCCCCEEEEEHHHHHHHHCCCCCCEEEEEECHHHHHHHHH
TAEKAGLLFPLSLAAEGSCTIGGNLATNAGGTQVVRYGNTRDLCLGLEVVTPQGEVWSGL
HHHHCCEEEEEEECCCCCEEECCCEECCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHH
KGLRKDNTGYDLRDLFIGSEGTLGIITAATMKLYPRPAASLTAWAAVPSMAHAVQLLALA
HHHCCCCCCCCHHHEEECCCCCEEEEEEEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHH
HGHLGASLTGFEVMGRFALSLVNKHMPQLRVPFIDQEEVPYGVLLENSDSESEEHARARF
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
EALLETAFEAGCVVDAVVAENLAQAHQLWHIRENIPLAQAEEGLNIKHDISVPISRIPAF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCHHHHHHH
VEHADALLQREIPGVRLVNFGHLGDGNLHYNVQAPAEGDAKAFLRDQEDRVNHLVYEAVA
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHH
AFGGSFSAEHGVGALKVDKLQQYQSPVALAMMRAIKGALDPQGLMNPQCMLPVRADQAIS
HHCCCCCCCCCCCCEEHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TASLIDTLRQIVGANHVLADGDLTAWEQDWRRRARGKALAVVRPASTAEVAAVVKACAA
CHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHH
HGTALVPQGGNTGLAVGSIPDASGTQVVLSLTRMNAVRNVDADNLTMTVEAGCILQNLQD
CCCEEEECCCCCCEEECCCCCCCCCEEEEEHHHHHHHHCCCCCCEEEEEECHHHHHHHHH
TAEKAGLLFPLSLAAEGSCTIGGNLATNAGGTQVVRYGNTRDLCLGLEVVTPQGEVWSGL
HHHHCCEEEEEEECCCCCEEECCCEECCCCCCEEEEECCCCCEEEEEEEECCCCHHHHHH
KGLRKDNTGYDLRDLFIGSEGTLGIITAATMKLYPRPAASLTAWAAVPSMAHAVQLLALA
HHHCCCCCCCCHHHEEECCCCCEEEEEEEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHH
HGHLGASLTGFEVMGRFALSLVNKHMPQLRVPFIDQEEVPYGVLLENSDSESEEHARARF
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
EALLETAFEAGCVVDAVVAENLAQAHQLWHIRENIPLAQAEEGLNIKHDISVPISRIPAF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCCCHHHHHHH
VEHADALLQREIPGVRLVNFGHLGDGNLHYNVQAPAEGDAKAFLRDQEDRVNHLVYEAVA
HHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCHHHHHCCCHHHHHHHHHHHHH
AFGGSFSAEHGVGALKVDKLQQYQSPVALAMMRAIKGALDPQGLMNPQCMLPVRADQAIS
HHCCCCCCCCCCCCEEHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]