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The map label for this gene is trpA [H]

Identifier: 120609901

GI number: 120609901

Start: 1336459

End: 1337316

Strand: Reverse

Name: trpA [H]

Synonym: Aave_1214

Alternate gene names: 120609901

Gene position: 1337316-1336459 (Counterclockwise)

Preceding gene: 120609902

Following gene: 120609900

Centisome position: 24.98

GC content: 69.58

Gene sequence:

>858_bases
ATGAGCGCCGACATGACGACTTCCGCGTCCACGGCACCGCTGGCCGCCCAGGGGCGCATCGCGGCGACGTTCGCCGACCT
GCAGGCCCGCGGCCGCAAGGCCCTCATTCCCTACGTGACCGCCGGCTTCCCGTTCGCGGACATCACGCCCGCGCTGATGC
ACGGCATGGTGGAGGCCGGCGCCGATGTGATCGAACTCGGCGTGCCGTTCTCCGATCCCATGGCCGACGGCCCGGTGATC
CAGAAGGCCGGGGAGAAGGCCCTCTCCCTGGGCGTGGGCATGGCCCAGGTGCTCGGCTATGTGCGCGAGTTCCGCCAGCG
CAACACGAAGACCCCGGTGGTGCTCATGGGCTACGCCAACCCGGTGGAACGCTACGACCAGCGCCACGGAGACAACGCCT
TCGTGCGCGATGCGGCCGAGGCCGGCGTGGACGGGGTACTGATCGTGGATTACCCTCCCGAAGAGTGCGAGGACTTCGCA
GCCCGGCTGCGCGCGCATGGCATGGACCTGATCTTCCTGCTGGCGCCCACCAGCACGGAGCAGCGCATGCAGCAGGTGGC
GCGCGTCGCGAGCGGCTACGTGTACTACGTTTCGCTCAAGGGCGTGACCGGCTCGGGCGCCCTCGATACTTCGGCCGTGG
AAGCCATGCTGCCGGTGATCCGCCGCCATGTGCACATCCCCGTCGGCGTGGGTTTCGGCATCCGCGATGCGGCCACCGCG
CAGGCCATCGGCCGTGTCGCGGATGCCGTGGTGATCGGCAGCCGCATCATCCAACTGCTGGAAGACCAGCCCCACGAGCG
GGTCGTGCCCCTGGCCGTGGACTTCCTGCGGGGGGTGCGCAAGGCGCTCGACACGTAG

Upstream 100 bases:

>100_bases
GGGGCGACAAGGACATCGGCACGGTGGCGGATCTCTCCGGCGTGGATTTCTACGACCGCCCGTCCATGCGGGGCCATGCC
GTCAAGGGAGGGCCCGCGGC

Downstream 100 bases:

>100_bases
AATCCAGGGATCATCCCCCTGAGCGGCTTTGCCGCTTCCCCCTTCTCTCGGCTTCGCCGGGAAGGGGGACGACGCCAACG
GCCCGGCCGAGCCGGTTCCG

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSADMTTSASTAPLAAQGRIAATFADLQARGRKALIPYVTAGFPFADITPALMHGMVEAGADVIELGVPFSDPMADGPVI
QKAGEKALSLGVGMAQVLGYVREFRQRNTKTPVVLMGYANPVERYDQRHGDNAFVRDAAEAGVDGVLIVDYPPEECEDFA
ARLRAHGMDLIFLLAPTSTEQRMQQVARVASGYVYYVSLKGVTGSGALDTSAVEAMLPVIRRHVHIPVGVGFGIRDAATA
QAIGRVADAVVIGSRIIQLLEDQPHERVVPLAVDFLRGVRKALDT

Sequences:

>Translated_285_residues
MSADMTTSASTAPLAAQGRIAATFADLQARGRKALIPYVTAGFPFADITPALMHGMVEAGADVIELGVPFSDPMADGPVI
QKAGEKALSLGVGMAQVLGYVREFRQRNTKTPVVLMGYANPVERYDQRHGDNAFVRDAAEAGVDGVLIVDYPPEECEDFA
ARLRAHGMDLIFLLAPTSTEQRMQQVARVASGYVYYVSLKGVTGSGALDTSAVEAMLPVIRRHVHIPVGVGFGIRDAATA
QAIGRVADAVVIGSRIIQLLEDQPHERVVPLAVDFLRGVRKALDT
>Mature_284_residues
SADMTTSASTAPLAAQGRIAATFADLQARGRKALIPYVTAGFPFADITPALMHGMVEAGADVIELGVPFSDPMADGPVIQ
KAGEKALSLGVGMAQVLGYVREFRQRNTKTPVVLMGYANPVERYDQRHGDNAFVRDAAEAGVDGVLIVDYPPEECEDFAA
RLRAHGMDLIFLLAPTSTEQRMQQVARVASGYVYYVSLKGVTGSGALDTSAVEAMLPVIRRHVHIPVGVGFGIRDAATAQ
AIGRVADAVVIGSRIIQLLEDQPHERVVPLAVDFLRGVRKALDT

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=216, Percent_Identity=34.7222222222222, Blast_Score=129, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321412, Length=262, Percent_Identity=37.7862595419847, Blast_Score=197, Evalue=2e-51,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 30398; Mature: 30267

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADMTTSASTAPLAAQGRIAATFADLQARGRKALIPYVTAGFPFADITPALMHGMVEAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCEEECCCCHHHCCHHHHHHHHHCC
ADVIELGVPFSDPMADGPVIQKAGEKALSLGVGMAQVLGYVREFRQRNTKTPVVLMGYAN
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCC
PVERYDQRHGDNAFVRDAAEAGVDGVLIVDYPPEECEDFAARLRAHGMDLIFLLAPTSTE
HHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCHH
QRMQQVARVASGYVYYVSLKGVTGSGALDTSAVEAMLPVIRRHVHIPVGVGFGIRDAATA
HHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHEECEEECCCCCCHHHHH
QAIGRVADAVVIGSRIIQLLEDQPHERVVPLAVDFLRGVRKALDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SADMTTSASTAPLAAQGRIAATFADLQARGRKALIPYVTAGFPFADITPALMHGMVEAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCEEECCCCHHHCCHHHHHHHHHCC
ADVIELGVPFSDPMADGPVIQKAGEKALSLGVGMAQVLGYVREFRQRNTKTPVVLMGYAN
CCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCC
PVERYDQRHGDNAFVRDAAEAGVDGVLIVDYPPEECEDFAARLRAHGMDLIFLLAPTSTE
HHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCHH
QRMQQVARVASGYVYYVSLKGVTGSGALDTSAVEAMLPVIRRHVHIPVGVGFGIRDAATA
HHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHEECEEECCCCCCHHHHH
QAIGRVADAVVIGSRIIQLLEDQPHERVVPLAVDFLRGVRKALDT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA