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The map label for this gene is ftsW [H]

Identifier: 120609514

GI number: 120609514

Start: 888012

End: 889295

Strand: Direct

Name: ftsW [H]

Synonym: Aave_0820

Alternate gene names: 120609514

Gene position: 888012-889295 (Clockwise)

Preceding gene: 120609513

Following gene: 120609515

Centisome position: 16.59

GC content: 67.99

Gene sequence:

>1284_bases
ATGAACGCGGGCGCTGCTGCATCTTCGTCGCGAGGCCTGCGCCACCGGATCGCCGGCTGGTTCGGGCGCGGCGCCTCGCC
CGCGGCCGACGTGCTGCCCGTGCGCGTGGGCGGCACGGAATACCGCCAGACCACGACCACCCCGGCGCGCGTGCTCGGGT
TCGACCAGGCCCTGCTCTGGGTGGTGGTGGCGCTGCTGGCCTGGGGGCTGGTCATGGTGTATTCGGCCTCCATCGCCATG
CCGGACAACCCGCGCTTCGGCAAGATCGCGCCCACCCATTTCCTCATGCGCCACATCATCGCGCTGGCGATGGGCTTCGT
CGCGGCGCTGCTCACCTTCCAGGTGCCCATGTCCGTCTGGGAGCGCGTCGCGCCCTGGCTGTTCATCGTTTCCATCGTGC
TGCTGGTGGCCGTGCTCGTGCCGCACGTGGGGACGGTGGTCAACGGCGCGCGGCGCTGGCTGTCGTTGGGCATCATGAAT
TTCCAGCCCTCCGAGCTCGCCAAGTTCGCGGTGCTGATCTACGCGGCCGACTACATGGTCCGCAAGATGGAAGTGAAGGA
GCGCTTCTTCCGCGCCGTGCTGCCCATGGGCGTGGCGGTGGCGGTCGTGGGCGTGCTGCTGCTGGCCGAACCCGACATGG
GTGCCTTCATGGTGATCGCCATCATCGCCATGGGCATCCTGTTCCTGGGCGGCGTCAACGCCCGCATGTTCTTCCTCATC
GCCGCCGTGCTGGTGCTGGCCTTCGCCATCATGGTCATGGGCAGCCCCTGGCGGCGCGAGCGGATCTTCGCCTACCTCGA
CCCCTTCAGCGAGGCGCACGCGCTCGGCAAGGGCTACCAGCTGTCGCACTCGCTCATCGCCATCGGCCGCGGCGAGATCT
TCGGCGTCGGCCTGGGCGGCAGCGTGGAGAAGCTGCACTGGCTGCCCGAAGCCCACACCGACTTCCTGCTCGCCGTGATC
GGCGAGGAATTCGGCCTGGTCGGCGTGCTGGTCGTGATCGCGCTGTTCTTCTGGATGACGCGCCGCATCATGCACATCGG
CCGCCAGGCCATCGCCCTGGACCGCGTCTTCGCGGGCCTCGTCGCGCAGGGCGTGGCGATCTGGATGGGCTTCCAGGCCT
TCATCAACATGGGCGTGAACCTCGGTGCCCTGCCCACCAAGGGCCTGACCCTGCCGCTCATGAGCTTCGGCGGCTCGGCC
ATCCTCATGAACCTCGTCGCGATCGCGGTGGTGCTGCGGGTGGATTATGAAAACAAGCACCTCATGCGCGGAGGCCGCGT
ATGA

Upstream 100 bases:

>100_bases
TCGACATGTTCCGCAACTACGAACACCGCGCCGAGGTGTTCCGCGAGGCCGTGCAGGCGCTCGCGGACGAGGCCGGACAG
GCGCTGGAAGGGGGGCTGGC

Downstream 100 bases:

>100_bases
GGTGCTTGTTTCGCCAAAACAATGCACTCGCCACGCGCCAGCGTGGTGAGGCGCGCAGCGCCATGCGCGGAGGCCGCGTA
TGACCCACCCCAGGACCGCC

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MNAGAAASSSRGLRHRIAGWFGRGASPAADVLPVRVGGTEYRQTTTTPARVLGFDQALLWVVVALLAWGLVMVYSASIAM
PDNPRFGKIAPTHFLMRHIIALAMGFVAALLTFQVPMSVWERVAPWLFIVSIVLLVAVLVPHVGTVVNGARRWLSLGIMN
FQPSELAKFAVLIYAADYMVRKMEVKERFFRAVLPMGVAVAVVGVLLLAEPDMGAFMVIAIIAMGILFLGGVNARMFFLI
AAVLVLAFAIMVMGSPWRRERIFAYLDPFSEAHALGKGYQLSHSLIAIGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVI
GEEFGLVGVLVVIALFFWMTRRIMHIGRQAIALDRVFAGLVAQGVAIWMGFQAFINMGVNLGALPTKGLTLPLMSFGGSA
ILMNLVAIAVVLRVDYENKHLMRGGRV

Sequences:

>Translated_427_residues
MNAGAAASSSRGLRHRIAGWFGRGASPAADVLPVRVGGTEYRQTTTTPARVLGFDQALLWVVVALLAWGLVMVYSASIAM
PDNPRFGKIAPTHFLMRHIIALAMGFVAALLTFQVPMSVWERVAPWLFIVSIVLLVAVLVPHVGTVVNGARRWLSLGIMN
FQPSELAKFAVLIYAADYMVRKMEVKERFFRAVLPMGVAVAVVGVLLLAEPDMGAFMVIAIIAMGILFLGGVNARMFFLI
AAVLVLAFAIMVMGSPWRRERIFAYLDPFSEAHALGKGYQLSHSLIAIGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVI
GEEFGLVGVLVVIALFFWMTRRIMHIGRQAIALDRVFAGLVAQGVAIWMGFQAFINMGVNLGALPTKGLTLPLMSFGGSA
ILMNLVAIAVVLRVDYENKHLMRGGRV
>Mature_427_residues
MNAGAAASSSRGLRHRIAGWFGRGASPAADVLPVRVGGTEYRQTTTTPARVLGFDQALLWVVVALLAWGLVMVYSASIAM
PDNPRFGKIAPTHFLMRHIIALAMGFVAALLTFQVPMSVWERVAPWLFIVSIVLLVAVLVPHVGTVVNGARRWLSLGIMN
FQPSELAKFAVLIYAADYMVRKMEVKERFFRAVLPMGVAVAVVGVLLLAEPDMGAFMVIAIIAMGILFLGGVNARMFFLI
AAVLVLAFAIMVMGSPWRRERIFAYLDPFSEAHALGKGYQLSHSLIAIGRGEIFGVGLGGSVEKLHWLPEAHTDFLLAVI
GEEFGLVGVLVVIALFFWMTRRIMHIGRQAIALDRVFAGLVAQGVAIWMGFQAFINMGVNLGALPTKGLTLPLMSFGGSA
ILMNLVAIAVVLRVDYENKHLMRGGRV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=385, Percent_Identity=42.0779220779221, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1786853, Length=334, Percent_Identity=36.5269461077844, Blast_Score=162, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46339; Mature: 46339

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCC
>Mature Secondary Structure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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]