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The map label for this gene is murG

Identifier: 120609515

GI number: 120609515

Start: 889375

End: 890442

Strand: Direct

Name: murG

Synonym: Aave_0821

Alternate gene names: 120609515

Gene position: 889375-890442 (Clockwise)

Preceding gene: 120609514

Following gene: 120609516

Centisome position: 16.62

GC content: 72.57

Gene sequence:

>1068_bases
ATGACCCACCCCAGGACCGCCCTCGTGATGGCCGGCGGCACCGGCGGCCACATCTTCCCCGGCCTGGCTGTGGCGGAAGA
GCTGCGTGCGCGCGGCTGGAAAGTGCACTGGCTGGGCACGCCCGGCAGCATGGAGTCGCGCATCGTGCCGCCGCAGGGCT
TCGCCTTCGAGCCGATCGACTTCTCGGGCGTGCGCGGCAAGGGCTTGGCCACGCTGGCGCTGCTGCCGCTGCGGCTGCTG
CGTGCGTTCTGGCAGGCGCTCGCGGTGGTGCGGCGCGTGCAGCCCGACGTGGTCGTGGGGCTGGGCGGCTATGTCACCTT
CCCCGGCGGCATGATGGCCGTGCTCTGCGGCAAGCCGCTCGTGGTGCACGAGCAGAATTCCGTGGCCGGCCTGGTCAACA
AGGTGCTGGCCGGCGTGGCCGACCGGGTCTTCACCGCCTTTCCCGGCGCGCTGCGCAAGGGCGCCTGGGTCGGCAACCCG
CTGCGCACCGCCTTCACGCGCCAGGCCGATCCGCAGGCGCGCTTCGCCGGCCGCGGCGGCCCGCTGCGCCTGCTGGTGGT
GGGCGGCAGCCTGGGCGCCAAGGCGCTCAACGACATCGTGCCGCAGGCGCTGGCCCTCATTCCCGCGGAGCGCCGCCCGG
TGGTCACCCACCAGAGCGGCACCGCCCAGATCGACGCGCTGCGCGCGAACTACGCCGCCGCGGGCGTCGAGGCCACGCTC
ACCCCTTTCATCGACGACACCGCCACCGCGTTCGCCGAGGCCGACCTCATCGTCTGCCGCGCGGGCGCGAGCACGGTGAC
CGAGATCGCCGCCGTGGGCGCGGCGGCCGTCTTCGTGCCCTTCCCGCACGCGGTGGACGACCACCAGACGGCCAACGCCC
GCTTCCTCGCCGACGCCGGCGGTGGATGGCTCGTGCAGCAGCGCGATCTCTCCGCCGAGGCGCTGGCGCAATTGCTACAA
AATACGGAGCGCGAAGCGCTGTTGGAGCGCGCGCTGAAAGCCAAGACGATGCAGAAGATCCACGCCACCCGCGAGGTGGC
GAACGCGTGCGAGGAATTGACCGCATGA

Upstream 100 bases:

>100_bases
ATGCGCGGAGGCCGCGTATGAGGTGCTTGTTTCGCCAAAACAATGCACTCGCCACGCGCCAGCGTGGTGAGGCGCGCAGC
GCCATGCGCGGAGGCCGCGT

Downstream 100 bases:

>100_bases
AGCACGCCATCCGCCACATCCATTTCGTGGGACTCGGGGGCGCCGGCATGTGCGGCATCGCCGAAGTGCTGTTCAACCTG
GGCTACGAGATCTCGGGCTC

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTHPRTALVMAGGTGGHIFPGLAVAEELRARGWKVHWLGTPGSMESRIVPPQGFAFEPIDFSGVRGKGLATLALLPLRLL
RAFWQALAVVRRVQPDVVVGLGGYVTFPGGMMAVLCGKPLVVHEQNSVAGLVNKVLAGVADRVFTAFPGALRKGAWVGNP
LRTAFTRQADPQARFAGRGGPLRLLVVGGSLGAKALNDIVPQALALIPAERRPVVTHQSGTAQIDALRANYAAAGVEATL
TPFIDDTATAFAEADLIVCRAGASTVTEIAAVGAAAVFVPFPHAVDDHQTANARFLADAGGGWLVQQRDLSAEALAQLLQ
NTEREALLERALKAKTMQKIHATREVANACEELTA

Sequences:

>Translated_355_residues
MTHPRTALVMAGGTGGHIFPGLAVAEELRARGWKVHWLGTPGSMESRIVPPQGFAFEPIDFSGVRGKGLATLALLPLRLL
RAFWQALAVVRRVQPDVVVGLGGYVTFPGGMMAVLCGKPLVVHEQNSVAGLVNKVLAGVADRVFTAFPGALRKGAWVGNP
LRTAFTRQADPQARFAGRGGPLRLLVVGGSLGAKALNDIVPQALALIPAERRPVVTHQSGTAQIDALRANYAAAGVEATL
TPFIDDTATAFAEADLIVCRAGASTVTEIAAVGAAAVFVPFPHAVDDHQTANARFLADAGGGWLVQQRDLSAEALAQLLQ
NTEREALLERALKAKTMQKIHATREVANACEELTA
>Mature_354_residues
THPRTALVMAGGTGGHIFPGLAVAEELRARGWKVHWLGTPGSMESRIVPPQGFAFEPIDFSGVRGKGLATLALLPLRLLR
AFWQALAVVRRVQPDVVVGLGGYVTFPGGMMAVLCGKPLVVHEQNSVAGLVNKVLAGVADRVFTAFPGALRKGAWVGNPL
RTAFTRQADPQARFAGRGGPLRLLVVGGSLGAKALNDIVPQALALIPAERRPVVTHQSGTAQIDALRANYAAAGVEATLT
PFIDDTATAFAEADLIVCRAGASTVTEIAAVGAAAVFVPFPHAVDDHQTANARFLADAGGGWLVQQRDLSAEALAQLLQN
TEREALLERALKAKTMQKIHATREVANACEELTA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=347, Percent_Identity=48.1268011527378, Blast_Score=296, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ACIAC (A1TKD1)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_969193.1
- ProteinModelPortal:   A1TKD1
- SMR:   A1TKD1
- STRING:   A1TKD1
- GeneID:   4668632
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0821
- NMPDR:   fig|397945.5.peg.712
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   A1TKD1
- ProtClustDB:   PRK00726
- BioCyc:   AAVE397945:AAVE_0821-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37329; Mature: 37197

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPRTALVMAGGTGGHIFPGLAVAEELRARGWKVHWLGTPGSMESRIVPPQGFAFEPID
CCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEECCCC
FSGVRGKGLATLALLPLRLLRAFWQALAVVRRVQPDVVVGLGGYVTFPGGMMAVLCGKPL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCHHHHHCCCEE
VVHEQNSVAGLVNKVLAGVADRVFTAFPGALRKGAWVGNPLRTAFTRQADPQARFAGRGG
EEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCCCCCCHHHCCCCC
PLRLLVVGGSLGAKALNDIVPQALALIPAERRPVVTHQSGTAQIDALRANYAAAGVEATL
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEHHHHHHHHHCCCCEEE
TPFIDDTATAFAEADLIVCRAGASTVTEIAAVGAAAVFVPFPHAVDDHQTANARFLADAG
CCCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECC
GGWLVQQRDLSAEALAQLLQNTEREALLERALKAKTMQKIHATREVANACEELTA
CCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THPRTALVMAGGTGGHIFPGLAVAEELRARGWKVHWLGTPGSMESRIVPPQGFAFEPID
CCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEECCCC
FSGVRGKGLATLALLPLRLLRAFWQALAVVRRVQPDVVVGLGGYVTFPGGMMAVLCGKPL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCHHHHHCCCEE
VVHEQNSVAGLVNKVLAGVADRVFTAFPGALRKGAWVGNPLRTAFTRQADPQARFAGRGG
EEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHCCCCCCHHHCCCCC
PLRLLVVGGSLGAKALNDIVPQALALIPAERRPVVTHQSGTAQIDALRANYAAAGVEATL
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEHHHHHHHHHCCCCEEE
TPFIDDTATAFAEADLIVCRAGASTVTEIAAVGAAAVFVPFPHAVDDHQTANARFLADAG
CCCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECC
GGWLVQQRDLSAEALAQLLQNTEREALLERALKAKTMQKIHATREVANACEELTA
CCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA