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The map label for this gene is recG [H]

Identifier: 120609293

GI number: 120609293

Start: 649080

End: 651206

Strand: Direct

Name: recG [H]

Synonym: Aave_0593

Alternate gene names: 120609293

Gene position: 649080-651206 (Clockwise)

Preceding gene: 120609289

Following gene: 120609294

Centisome position: 12.13

GC content: 72.31

Gene sequence:

>2127_bases
ATGCCCGCTCCCGCGCCCAGTCCCGCCCAGAAAGCCCTCCAGAAGCTGGGACTGTCGCGCGACATCGACCTCGCGCTGCA
CCTGCCCCTGCGCTACGAGGACGAAACCCGCATCACCCCCCTGCGCAACGTGCGGGATGGCGACACGGCCCAGATCGAGG
CCACGGTCACGGCGAGCGAAGTGCAGTTGCGCCCGCGCCGCCAGCTGGTGGTGACGGTGGACGACGGCACGGGTACCTGC
GAGCTGCGCTTCTTCAGTTTCTATCCTTCCCACCAGAAGACCCTGGCCGTCGGAGCGCGCCTGCGCATCCGCGGTGAGGT
CAAGGGGGGCTTCTGGGGGCGGCAGATGCTGCATCCGGCGTTCCGGCTGGCGGGCGGCGAACTGCCCGCCGCCCTCACGC
CGGTCTATCCGACCACGGCCGGCCTGCCCCAGCCCTATCTGCGCCGGGCCATCGTGAGCGCCCTGCAGCGCGTAGACCTG
TCCGAAACCATCCCCCCGGGGCTGGAACCTCCGATCCCGCGGTTCCTGGGCGAGGGCGGCGGGGGCCGCTCCTGGTGGAC
GCTGCGCGACGCGCTGGTGTTCCTGCACCATCCCACACCCGACGTGGCCTTGGCCACGCTGGAGGACCACAGCCATCCTG
CCTGGCAGCGGCTGAAGGCCGAGGAACTGCTCGCGCAGCAGCTCTCGCAGCTGGAGGCCAAGCGCGAGCGCGACCGGCTG
CGCGCGCCGGTGCTGCGGCCCGCGCCGGGCGGGGAGGGGGGAGCCGCGCTGCACGAACGCCTGCTGGCCGCATTGCCCTT
CGGCCTGACCGCCGCCCAGCGGCGCGTGTGCGCCGAGATCGCGGCAGACCTCGCCCGCGCCGTGCCCATGCACCGGCTCC
TGCAGGGCGACGTGGGCTCGGGCAAGACCGTGGTGGCTGCGCTCTCGGCGGCCGTGTGCATGGATGCGGGCTGGCAGTGC
GCGCTCATGGCGCCCACCGAGATCCTGGCCGAACAGCACTTCCGCAAGCTCATCGGCTGGCTGGAGCCCCTGCTCGCGGC
CAGTGGACGGCGCGTGGCCTGGCTGGCTGGCGGCCAGAAGAAGAAGGAGCGCGCCGCCATGCTGGCGCTGGTGGAAAGCG
GCGAGGCGGCGCTGGTCGTGGGCACCCACGCGGTGATCCAGGAGCAGGTGCGCTTCCGCAACCTCGCGCTGGCCGTCATC
GACGAGCAGCACCGCTTCGGCGTGGCGCAGCGGCTCGCGCTGCGCCGCAAGCTCGCCGACCAGGGCATGGAGCCGCACCT
GCTGATGATGAGCGCCACGCCGATCCCGCGCACGCTCGCCATGAGCTACTACGCCGACCTCGACGTCTCCACCATCGACG
AGCTGCCCCCCGGCCGCACGCCCATCGTCACCAAACTGATCGCCGACAGCCGCAAGGACGAGGTCATCGAGCGCATCGGC
GCGCAGGTGGCGTCCGGCCGGCAGGTGTACTGGGTCTGCCCGCTCATCGAGGAGAGTGAGGCGCTGGACCTCTCCAACGC
CACCGCCACGCACCTGGAACTCAGCGAGGCCCTGCAGGGCGATCCGGCGCACGGGCAGGCGCCGGTCATGGTGGGCCTGC
TGCACTCCCGCATGCCCCCGGCCGAGAAGAAGGCCGTCATGGAACTGTTCACCGCCGGCACCATGGGCGTGCTCGTCTCC
ACCACGGTGATCGAGGTGGGCGTGGACGTGCCCAACGCATCGCTCATGGTGATCGAGCATGCCGAGCGGTTCGGCCTCTC
GCAGCTGCACCAGCTGCGCGGCCGCGTGGGCCGCGGGTCGGCGGCGTCGGCCTGCGTGCTGCTCTATTCGACGGGCGAGA
GCGGCCGGCTGGGCGAGACCGCGCGCGACCGCCTGCGGGCCATGGCGGAAACCCAGGATGGCTTCGAGATCGCGCGGCGC
GACCTGGAAATCCGCGGCCCCGGCGAATTCCTCGGCGCCCGCCAGTCCGGCGCGCCGATGCTGCGCTTCGCGGACCTCGC
CACCGACACCCTGCTGCTGGAGTGGGCGCGCGAGACGGCCCCGCGCATGCTCGACGGGCATCCCGGCGACGCGCGCCGCC
ATGTGGGCCGCTGGCTCGGCGGCAAGGCCGATTACCTCAAGGCCTGA

Upstream 100 bases:

>100_bases
TGGAGCGTGCGGCAAGCCGTTTCCATTTTTGCAGTTATTGCGGATTTTGCCATTTCTGCGCGGCAAGCACTGTTTCCTCC
GCTCTCCCGTCGTTTCGCCC

Downstream 100 bases:

>100_bases
TCCGGCGGTCCTGCATCCGTGGCAGACTTGGCGGCCCGTCGCCACGGTCCGCATTCCGTGTCGCGGGCGCACAATCGCAC
CTTCCGCATTGCCGACCCTT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MPAPAPSPAQKALQKLGLSRDIDLALHLPLRYEDETRITPLRNVRDGDTAQIEATVTASEVQLRPRRQLVVTVDDGTGTC
ELRFFSFYPSHQKTLAVGARLRIRGEVKGGFWGRQMLHPAFRLAGGELPAALTPVYPTTAGLPQPYLRRAIVSALQRVDL
SETIPPGLEPPIPRFLGEGGGGRSWWTLRDALVFLHHPTPDVALATLEDHSHPAWQRLKAEELLAQQLSQLEAKRERDRL
RAPVLRPAPGGEGGAALHERLLAALPFGLTAAQRRVCAEIAADLARAVPMHRLLQGDVGSGKTVVAALSAAVCMDAGWQC
ALMAPTEILAEQHFRKLIGWLEPLLAASGRRVAWLAGGQKKKERAAMLALVESGEAALVVGTHAVIQEQVRFRNLALAVI
DEQHRFGVAQRLALRRKLADQGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTKLIADSRKDEVIERIG
AQVASGRQVYWVCPLIEESEALDLSNATATHLELSEALQGDPAHGQAPVMVGLLHSRMPPAEKKAVMELFTAGTMGVLVS
TTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGSAASACVLLYSTGESGRLGETARDRLRAMAETQDGFEIARR
DLEIRGPGEFLGARQSGAPMLRFADLATDTLLLEWARETAPRMLDGHPGDARRHVGRWLGGKADYLKA

Sequences:

>Translated_708_residues
MPAPAPSPAQKALQKLGLSRDIDLALHLPLRYEDETRITPLRNVRDGDTAQIEATVTASEVQLRPRRQLVVTVDDGTGTC
ELRFFSFYPSHQKTLAVGARLRIRGEVKGGFWGRQMLHPAFRLAGGELPAALTPVYPTTAGLPQPYLRRAIVSALQRVDL
SETIPPGLEPPIPRFLGEGGGGRSWWTLRDALVFLHHPTPDVALATLEDHSHPAWQRLKAEELLAQQLSQLEAKRERDRL
RAPVLRPAPGGEGGAALHERLLAALPFGLTAAQRRVCAEIAADLARAVPMHRLLQGDVGSGKTVVAALSAAVCMDAGWQC
ALMAPTEILAEQHFRKLIGWLEPLLAASGRRVAWLAGGQKKKERAAMLALVESGEAALVVGTHAVIQEQVRFRNLALAVI
DEQHRFGVAQRLALRRKLADQGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTKLIADSRKDEVIERIG
AQVASGRQVYWVCPLIEESEALDLSNATATHLELSEALQGDPAHGQAPVMVGLLHSRMPPAEKKAVMELFTAGTMGVLVS
TTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGSAASACVLLYSTGESGRLGETARDRLRAMAETQDGFEIARR
DLEIRGPGEFLGARQSGAPMLRFADLATDTLLLEWARETAPRMLDGHPGDARRHVGRWLGGKADYLKA
>Mature_707_residues
PAPAPSPAQKALQKLGLSRDIDLALHLPLRYEDETRITPLRNVRDGDTAQIEATVTASEVQLRPRRQLVVTVDDGTGTCE
LRFFSFYPSHQKTLAVGARLRIRGEVKGGFWGRQMLHPAFRLAGGELPAALTPVYPTTAGLPQPYLRRAIVSALQRVDLS
ETIPPGLEPPIPRFLGEGGGGRSWWTLRDALVFLHHPTPDVALATLEDHSHPAWQRLKAEELLAQQLSQLEAKRERDRLR
APVLRPAPGGEGGAALHERLLAALPFGLTAAQRRVCAEIAADLARAVPMHRLLQGDVGSGKTVVAALSAAVCMDAGWQCA
LMAPTEILAEQHFRKLIGWLEPLLAASGRRVAWLAGGQKKKERAAMLALVESGEAALVVGTHAVIQEQVRFRNLALAVID
EQHRFGVAQRLALRRKLADQGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTKLIADSRKDEVIERIGA
QVASGRQVYWVCPLIEESEALDLSNATATHLELSEALQGDPAHGQAPVMVGLLHSRMPPAEKKAVMELFTAGTMGVLVST
TVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGSAASACVLLYSTGESGRLGETARDRLRAMAETQDGFEIARRD
LEIRGPGEFLGARQSGAPMLRFADLATDTLLLEWARETAPRMLDGHPGDARRHVGRWLGGKADYLKA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=706, Percent_Identity=48.1586402266289, Blast_Score=578, Evalue=1e-166,
Organism=Escherichia coli, GI1787357, Length=417, Percent_Identity=35.2517985611511, Blast_Score=216, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76998; Mature: 76867

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPAPSPAQKALQKLGLSRDIDLALHLPLRYEDETRITPLRNVRDGDTAQIEATVTASE
CCCCCCCHHHHHHHHCCCCCCCCEEEECCEEECCCCCCCCCCCCCCCCCEEEEEEEEHHH
VQLRPRRQLVVTVDDGTGTCELRFFSFYPSHQKTLAVGARLRIRGEVKGGFWGRQMLHPA
HEECCCEEEEEEEECCCCEEEEEEEEECCCCCCEEEECEEEEEEEECCCCCCHHHHHHHH
FRLAGGELPAALTPVYPTTAGLPQPYLRRAIVSALQRVDLSETIPPGLEPPIPRFLGEGG
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHCCCC
GGRSWWTLRDALVFLHHPTPDVALATLEDHSHPAWQRLKAEELLAQQLSQLEAKRERDRL
CCCCHHHHHHEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAPVLRPAPGGEGGAALHERLLAALPFGLTAAQRRVCAEIAADLARAVPMHRLLQGDVGS
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKTVVAALSAAVCMDAGWQCALMAPTEILAEQHFRKLIGWLEPLLAASGRRVAWLAGGQK
CHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
KKERAAMLALVESGEAALVVGTHAVIQEQVRFRNLALAVIDEQHRFGVAQRLALRRKLAD
HHHHHHHHHHEECCCEEEEECHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHH
QGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTKLIADSRKDEVIERIG
CCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHH
AQVASGRQVYWVCPLIEESEALDLSNATATHLELSEALQGDPAHGQAPVMVGLLHSRMPP
HHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
AEKKAVMELFTAGTMGVLVSTTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGS
HHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCEEEEECHHHCCHHHHHHHHCCCCCCC
AASACVLLYSTGESGRLGETARDRLRAMAETQDGFEIARRDLEIRGPGEFLGARQSGAPM
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHCCCCCCCCC
LRFADLATDTLLLEWARETAPRMLDGHPGDARRHVGRWLGGKADYLKA
EEHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure 
PAPAPSPAQKALQKLGLSRDIDLALHLPLRYEDETRITPLRNVRDGDTAQIEATVTASE
CCCCCCHHHHHHHHCCCCCCCCEEEECCEEECCCCCCCCCCCCCCCCCEEEEEEEEHHH
VQLRPRRQLVVTVDDGTGTCELRFFSFYPSHQKTLAVGARLRIRGEVKGGFWGRQMLHPA
HEECCCEEEEEEEECCCCEEEEEEEEECCCCCCEEEECEEEEEEEECCCCCCHHHHHHHH
FRLAGGELPAALTPVYPTTAGLPQPYLRRAIVSALQRVDLSETIPPGLEPPIPRFLGEGG
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHCCCC
GGRSWWTLRDALVFLHHPTPDVALATLEDHSHPAWQRLKAEELLAQQLSQLEAKRERDRL
CCCCHHHHHHEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAPVLRPAPGGEGGAALHERLLAALPFGLTAAQRRVCAEIAADLARAVPMHRLLQGDVGS
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GKTVVAALSAAVCMDAGWQCALMAPTEILAEQHFRKLIGWLEPLLAASGRRVAWLAGGQK
CHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
KKERAAMLALVESGEAALVVGTHAVIQEQVRFRNLALAVIDEQHRFGVAQRLALRRKLAD
HHHHHHHHHHEECCCEEEEECHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHH
QGMEPHLLMMSATPIPRTLAMSYYADLDVSTIDELPPGRTPIVTKLIADSRKDEVIERIG
CCCCCEEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHH
AQVASGRQVYWVCPLIEESEALDLSNATATHLELSEALQGDPAHGQAPVMVGLLHSRMPP
HHHHCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
AEKKAVMELFTAGTMGVLVSTTVIEVGVDVPNASLMVIEHAERFGLSQLHQLRGRVGRGS
HHHHHHHHHHHCCHHHHHHHHHHEEEECCCCCCCEEEEECHHHCCHHHHHHHHCCCCCCC
AASACVLLYSTGESGRLGETARDRLRAMAETQDGFEIARRDLEIRGPGEFLGARQSGAPM
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCEECCCHHHHCCCCCCCCC
LRFADLATDTLLLEWARETAPRMLDGHPGDARRHVGRWLGGKADYLKA
EEHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]