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The map label for this gene is groL3

Identifier: 119946417

GI number: 119946417

Start: 3433557

End: 3435191

Strand: Direct

Name: groL3

Synonym: Ping_2791

Alternate gene names: 119946417

Gene position: 3433557-3435191 (Clockwise)

Preceding gene: 119946403

Following gene: 119946418

Centisome position: 75.3

GC content: 38.35

Gene sequence:

>1635_bases
ATGTCAGCTAAAGCGATTAAATTTAACCACCATGCCCGTGAGAAGATGTTAAAAGGAGTTAACATCTTAGCCGATTCGGT
TAAAGTGACTTTAGGTCCAAAGGGGCGAAATGTTGTTATTGCCCAAAAATACAGCCGTCCCATTATTACTAAAGATGGGG
TCACCGTTGCGAAAGAAATTGAATTAATTGACCCTTTTGAAAACATGGGTGCCCAGTTGACAAAAGAAGTCGCCTTTCAG
GCAAGTGACAGTGCTGGTGATGGCACCACAACAGCAACTGTATTAACTCAAGCTATTGTTAATGAAGGTGTGAATGCAAT
ATCAGCTAATATGAACCCGATTGATTTAAAGAAAGGGATTGATAAATGCTTACACTATGCTCTGCTCGAATTAAATTTAT
TATCTCAAAATTGTGATAACTTAGAAAAAGCCGAACAAATTGCGACTATTTCAGCCAACGGTGAGGAACAGATTGGTAAA
TTAATTGCACAAGCAATGGAAAGAATTGGAACCGATGGTGTTGTTAGTGTCGAAGATGCTCAAGGATACGATGATGAATT
GATTTTTAAAGAAGGACTCGCCTTTGATCGTGGTTACCTATCACCGTATTTTATTAACAATCATGAAAAATCGACAGTTG
AATTAAATAACCCTTCTATTTTACTACTTGATGATAAATTAACCCATATGGAGGACTTACTTCCTTTACTTGAAAAGTTA
GCAAACAATCGTAACCCGCTTCTTGTGATTGCAGAAGACATTAACAATGAGGTTTTATCGCGGATCATTGGTAATAATAT
GAAAAACAATCTAAAAGTGACTGTTATTAAATCACCCGCATTCGGTAGCAGACGGACTGAGATATTACAAGATTTAGCTA
TTTATACCGGTGGTACAGTTATTTCGCCTGAGATTGGCATGGATCTGTCGGAGGTGGATACCGATAAACTGGGTAATGCT
TCAAAAATTATTATTACAGATTCAAACACCACTATTGTTCACGGTGAAGGCGATCCGCAACTTATTATGCAACGAATTAA
ACAATTAAATTCTCAACTCCTTAATTCATCTTCTGAATATGACCAGAAAAAATTAGCCGAACGTGTTGCTAAATTATCGG
GTGCTATCGCCATCATTAAGGTCGGCGCTGCGACAGAAGTCGCCATGAAGGAAAAAAAGGATCGTGTTGAAGATGCCTTG
CATGCAACAAAAGCAGCCATTAAAGAAGGTATTGTACCAGGAGGCGGCGTTGCATATATACGTATAGCACAAACTCTCGC
TTCTCTTGAGGGCGACAATCCGGATCAGAGCTTTGGCATTAAAATTTTACTTAAAGCCATGGAATCGCCATTAAAGCAAA
TTGCTAAAAATGCTGGAAATGAACCTGTTGAAGTGCTTAGTACAATTAAAAAGCAAACCGGAAATTTTGGTTTTGATGCA
AAAAACGATCGATATGGTGACATGATGGAGTTTGGTATTATTGACCCAACAAAAGTAACACGTTGTGCTTTAGAGTTTGC
AGCATCTATCGCGAGTTTGATTTTGACAACAGAGGTAATGGTTGCAGATATGGAAGACAATAACGCAAATCATGCAAATC
ATGACCATGCCCATAGTTTAAACTGCAGCCACTAA

Upstream 100 bases:

>100_bases
CAACCCACTTGAAAAATTAAATTGACTTAAAACCCCCATAGTGGTGCAATCGTTTGCACAAACTGAATATCTACTGTTAC
CAAATAAGGATTATTTAAAT

Downstream 100 bases:

>100_bases
AAATCATGCAGGATAAAATTACGCGCGCTCAAACAATAAGCTGCATAATTTTATCCTGATACTCTGTAGAAACATCCTGT
TTCCACTTGCTAACATTATT

Product: chaperonin Cpn60, GroEL, large subunit of GroESL

Products: NA

Alternate protein names: GroEL protein 3; Protein Cpn60 3

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSAKAIKFNHHAREKMLKGVNILADSVKVTLGPKGRNVVIAQKYSRPIITKDGVTVAKEIELIDPFENMGAQLTKEVAFQ
ASDSAGDGTTTATVLTQAIVNEGVNAISANMNPIDLKKGIDKCLHYALLELNLLSQNCDNLEKAEQIATISANGEEQIGK
LIAQAMERIGTDGVVSVEDAQGYDDELIFKEGLAFDRGYLSPYFINNHEKSTVELNNPSILLLDDKLTHMEDLLPLLEKL
ANNRNPLLVIAEDINNEVLSRIIGNNMKNNLKVTVIKSPAFGSRRTEILQDLAIYTGGTVISPEIGMDLSEVDTDKLGNA
SKIIITDSNTTIVHGEGDPQLIMQRIKQLNSQLLNSSSEYDQKKLAERVAKLSGAIAIIKVGAATEVAMKEKKDRVEDAL
HATKAAIKEGIVPGGGVAYIRIAQTLASLEGDNPDQSFGIKILLKAMESPLKQIAKNAGNEPVEVLSTIKKQTGNFGFDA
KNDRYGDMMEFGIIDPTKVTRCALEFAASIASLILTTEVMVADMEDNNANHANHDHAHSLNCSH

Sequences:

>Translated_544_residues
MSAKAIKFNHHAREKMLKGVNILADSVKVTLGPKGRNVVIAQKYSRPIITKDGVTVAKEIELIDPFENMGAQLTKEVAFQ
ASDSAGDGTTTATVLTQAIVNEGVNAISANMNPIDLKKGIDKCLHYALLELNLLSQNCDNLEKAEQIATISANGEEQIGK
LIAQAMERIGTDGVVSVEDAQGYDDELIFKEGLAFDRGYLSPYFINNHEKSTVELNNPSILLLDDKLTHMEDLLPLLEKL
ANNRNPLLVIAEDINNEVLSRIIGNNMKNNLKVTVIKSPAFGSRRTEILQDLAIYTGGTVISPEIGMDLSEVDTDKLGNA
SKIIITDSNTTIVHGEGDPQLIMQRIKQLNSQLLNSSSEYDQKKLAERVAKLSGAIAIIKVGAATEVAMKEKKDRVEDAL
HATKAAIKEGIVPGGGVAYIRIAQTLASLEGDNPDQSFGIKILLKAMESPLKQIAKNAGNEPVEVLSTIKKQTGNFGFDA
KNDRYGDMMEFGIIDPTKVTRCALEFAASIASLILTTEVMVADMEDNNANHANHDHAHSLNCSH
>Mature_543_residues
SAKAIKFNHHAREKMLKGVNILADSVKVTLGPKGRNVVIAQKYSRPIITKDGVTVAKEIELIDPFENMGAQLTKEVAFQA
SDSAGDGTTTATVLTQAIVNEGVNAISANMNPIDLKKGIDKCLHYALLELNLLSQNCDNLEKAEQIATISANGEEQIGKL
IAQAMERIGTDGVVSVEDAQGYDDELIFKEGLAFDRGYLSPYFINNHEKSTVELNNPSILLLDDKLTHMEDLLPLLEKLA
NNRNPLLVIAEDINNEVLSRIIGNNMKNNLKVTVIKSPAFGSRRTEILQDLAIYTGGTVISPEIGMDLSEVDTDKLGNAS
KIIITDSNTTIVHGEGDPQLIMQRIKQLNSQLLNSSSEYDQKKLAERVAKLSGAIAIIKVGAATEVAMKEKKDRVEDALH
ATKAAIKEGIVPGGGVAYIRIAQTLASLEGDNPDQSFGIKILLKAMESPLKQIAKNAGNEPVEVLSTIKKQTGNFGFDAK
NDRYGDMMEFGIIDPTKVTRCALEFAASIASLILTTEVMVADMEDNNANHANHDHAHSLNCSH

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family

Homologues:

Organism=Homo sapiens, GI41399285, Length=523, Percent_Identity=43.9770554493308, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI31542947, Length=523, Percent_Identity=43.9770554493308, Blast_Score=445, Evalue=1e-125,
Organism=Escherichia coli, GI1790586, Length=529, Percent_Identity=55.9546313799622, Blast_Score=620, Evalue=1e-179,
Organism=Caenorhabditis elegans, GI17555558, Length=533, Percent_Identity=44.0900562851782, Blast_Score=459, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI193210679, Length=243, Percent_Identity=43.2098765432099, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6323288, Length=526, Percent_Identity=44.106463878327, Blast_Score=456, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6322350, Length=551, Percent_Identity=22.1415607985481, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641193, Length=523, Percent_Identity=43.7858508604207, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24641191, Length=523, Percent_Identity=43.7858508604207, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI45550936, Length=523, Percent_Identity=43.0210325047801, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI45550132, Length=523, Percent_Identity=43.0210325047801, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI45550935, Length=523, Percent_Identity=43.0210325047801, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI17864606, Length=530, Percent_Identity=38.6792452830189, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24584129, Length=526, Percent_Identity=35.171102661597, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI19921262, Length=526, Percent_Identity=35.171102661597, Blast_Score=309, Evalue=3e-84,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): CH603_PSYIN (A1SYD3)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944097.1
- ProteinModelPortal:   A1SYD3
- SMR:   A1SYD3
- STRING:   A1SYD3
- GeneID:   4626786
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2791
- eggNOG:   COG0459
- HOGENOM:   HBG625289
- OMA:   CANADNE
- PhylomeDB:   A1SYD3
- BioCyc:   PING357804:PING_2791-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00600
- InterPro:   IPR001844
- InterPro:   IPR002423
- PANTHER:   PTHR11353
- PRINTS:   PR00298
- TIGRFAMs:   TIGR02348

Pfam domain/function: PF00118 Cpn60_TCP1; SSF48592 GroEL-ATPase

EC number: NA

Molecular weight: Translated: 59019; Mature: 58888

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKAIKFNHHAREKMLKGVNILADSVKVTLGPKGRNVVIAQKYSRPIITKDGVTVAKEI
CCCCEEECCHHHHHHHHHHHHHEECCEEEEECCCCCEEEEEECCCCCCEECCCCCHHHHH
ELIDPFENMGAQLTKEVAFQASDSAGDGTTTATVLTQAIVNEGVNAISANMNPIDLKKGI
EEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHH
DKCLHYALLELNLLSQNCDNLEKAEQIATISANGEEQIGKLIAQAMERIGTDGVVSVEDA
HHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCC
QGYDDELIFKEGLAFDRGYLSPYFINNHEKSTVELNNPSILLLDDKLTHMEDLLPLLEKL
CCCCCHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHH
ANNRNPLLVIAEDINNEVLSRIIGNNMKNNLKVTVIKSPAFGSRRTEILQDLAIYTGGTV
HCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEE
ISPEIGMDLSEVDTDKLGNASKIIITDSNTTIVHGEGDPQLIMQRIKQLNSQLLNSSSEY
ECHHHCCCHHHCCHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHH
DQKKLAERVAKLSGAIAIIKVGAATEVAMKEKKDRVEDALHATKAAIKEGIVPGGGVAYI
HHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RIAQTLASLEGDNPDQSFGIKILLKAMESPLKQIAKNAGNEPVEVLSTIKKQTGNFGFDA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
KNDRYGDMMEFGIIDPTKVTRCALEFAASIASLILTTEVMVADMEDNNANHANHDHAHSL
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCC
NCSH
CCCC
>Mature Secondary Structure 
SAKAIKFNHHAREKMLKGVNILADSVKVTLGPKGRNVVIAQKYSRPIITKDGVTVAKEI
CCCEEECCHHHHHHHHHHHHHEECCEEEEECCCCCEEEEEECCCCCCEECCCCCHHHHH
ELIDPFENMGAQLTKEVAFQASDSAGDGTTTATVLTQAIVNEGVNAISANMNPIDLKKGI
EEECCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHH
DKCLHYALLELNLLSQNCDNLEKAEQIATISANGEEQIGKLIAQAMERIGTDGVVSVEDA
HHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCC
QGYDDELIFKEGLAFDRGYLSPYFINNHEKSTVELNNPSILLLDDKLTHMEDLLPLLEKL
CCCCCHHHHHHCCCCCCCCCCCEEECCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHH
ANNRNPLLVIAEDINNEVLSRIIGNNMKNNLKVTVIKSPAFGSRRTEILQDLAIYTGGTV
HCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEE
ISPEIGMDLSEVDTDKLGNASKIIITDSNTTIVHGEGDPQLIMQRIKQLNSQLLNSSSEY
ECHHHCCCHHHCCHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHH
DQKKLAERVAKLSGAIAIIKVGAATEVAMKEKKDRVEDALHATKAAIKEGIVPGGGVAYI
HHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
RIAQTLASLEGDNPDQSFGIKILLKAMESPLKQIAKNAGNEPVEVLSTIKKQTGNFGFDA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCC
KNDRYGDMMEFGIIDPTKVTRCALEFAASIASLILTTEVMVADMEDNNANHANHDHAHSL
CCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCC
NCSH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA