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The map label for this gene is bioD [H]

Identifier: 119945612

GI number: 119945612

Start: 2346768

End: 2347475

Strand: Reverse

Name: bioD [H]

Synonym: Ping_1921

Alternate gene names: 119945612

Gene position: 2347475-2346768 (Counterclockwise)

Preceding gene: 119945613

Following gene: 119945611

Centisome position: 51.48

GC content: 36.58

Gene sequence:

>708_bases
ATGCAACCTTTTTTAACACCTGATATTTATTTTGTAACCGGAACAGATACTGATGTGGGTAAAACAGTTTGTTGTCAAGC
TTTGTTACAAGCTGCTAATAAACAAAAACTTCGTACCTTAGCCTACAAGCCTATCGCGGCAGGATGTGAGCAAACTCCAT
ACGGATTACGTAATCATGATGCGCAGCTTCTGCAAAAGACCTGTAATCTGGAAGTTGCTTATAAATGGGTTAATCCAATT
GCGTTTACACCGGCTATCGCGCCACATATCGCTGCACAATTAGAAAATAAACCCATTGAACAGTCTTATATTTCTCAAGG
TTTGGAAAGATTAAAGTCCTTGGAGAGTGATTTAATTATTGTTGAAGGGGCTGGTGGATGGCGTTTACCATTAAGTGCGG
ATGAAACGCTATCAGATTGGGTAGCAACACAAAAATTATCAGTTATATTGGTAGTGGGTATGAAATTGGGGTGTTTAAAT
CATGCGATTTTAACCTATGAAAGTATTCTTAATGATGGATTAAAGGTAGTGGGGTGGATAGCCAATCAAGTCGAAAAGAA
CATGCCTTTTTATACCTTAAATATAGAAATGTTAAAACATAAGATTAACGCGCCTATGATCGCAGAAATTCCTTATTTAC
ACAATATAAACGAACAGGATCTCTCTTCTTATGTTTATTTTAATTTCGCAACTAATGAGATGATTTGA

Upstream 100 bases:

>100_bases
GTATAAAGGCGATCTAAATAATATAAACGCTAATTGTAAAACCGCATAAACTTTATATCTTCTTTCCAGCAAGTTAATTA
CTCAAAAGTGATCAAATAAT

Downstream 100 bases:

>100_bases
GTCGCACTTTCTTTTGTATTGACAAAAACCAGGGCGGTTTCGCTCGATTTTATTGAAATAAAAACAAACACTTTTTATAA
ACTACAAAATATTATTTATG

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQPFLTPDIYFVTGTDTDVGKTVCCQALLQAANKQKLRTLAYKPIAAGCEQTPYGLRNHDAQLLQKTCNLEVAYKWVNPI
AFTPAIAPHIAAQLENKPIEQSYISQGLERLKSLESDLIIVEGAGGWRLPLSADETLSDWVATQKLSVILVVGMKLGCLN
HAILTYESILNDGLKVVGWIANQVEKNMPFYTLNIEMLKHKINAPMIAEIPYLHNINEQDLSSYVYFNFATNEMI

Sequences:

>Translated_235_residues
MQPFLTPDIYFVTGTDTDVGKTVCCQALLQAANKQKLRTLAYKPIAAGCEQTPYGLRNHDAQLLQKTCNLEVAYKWVNPI
AFTPAIAPHIAAQLENKPIEQSYISQGLERLKSLESDLIIVEGAGGWRLPLSADETLSDWVATQKLSVILVVGMKLGCLN
HAILTYESILNDGLKVVGWIANQVEKNMPFYTLNIEMLKHKINAPMIAEIPYLHNINEQDLSSYVYFNFATNEMI
>Mature_235_residues
MQPFLTPDIYFVTGTDTDVGKTVCCQALLQAANKQKLRTLAYKPIAAGCEQTPYGLRNHDAQLLQKTCNLEVAYKWVNPI
AFTPAIAPHIAAQLENKPIEQSYISQGLERLKSLESDLIIVEGAGGWRLPLSADETLSDWVATQKLSVILVVGMKLGCLN
HAILTYESILNDGLKVVGWIANQVEKNMPFYTLNIEMLKHKINAPMIAEIPYLHNINEQDLSSYVYFNFATNEMI

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=221, Percent_Identity=47.5113122171946, Blast_Score=203, Evalue=7e-54,
Organism=Escherichia coli, GI87081944, Length=218, Percent_Identity=42.2018348623853, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 26242; Mature: 26242

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPFLTPDIYFVTGTDTDVGKTVCCQALLQAANKQKLRTLAYKPIAAGCEQTPYGLRNHD
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCHHHCCCCCCCCCCCCCH
AQLLQKTCNLEVAYKWVNPIAFTPAIAPHIAAQLENKPIEQSYISQGLERLKSLESDLII
HHHHHHHCCCEEEEEECCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEE
VEGAGGWRLPLSADETLSDWVATQKLSVILVVGMKLGCLNHAILTYESILNDGLKVVGWI
EECCCCEECCCCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ANQVEKNMPFYTLNIEMLKHKINAPMIAEIPYLHNINEQDLSSYVYFNFATNEMI
HHHHHHCCCEEEEEHHHHHHHCCCCEEEECCHHHCCCHHHHCEEEEEEECCCCCC
>Mature Secondary Structure
MQPFLTPDIYFVTGTDTDVGKTVCCQALLQAANKQKLRTLAYKPIAAGCEQTPYGLRNHD
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCHHHHHHHHCCHHHCCCCCCCCCCCCCH
AQLLQKTCNLEVAYKWVNPIAFTPAIAPHIAAQLENKPIEQSYISQGLERLKSLESDLII
HHHHHHHCCCEEEEEECCCEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEE
VEGAGGWRLPLSADETLSDWVATQKLSVILVVGMKLGCLNHAILTYESILNDGLKVVGWI
EECCCCEECCCCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ANQVEKNMPFYTLNIEMLKHKINAPMIAEIPYLHNINEQDLSSYVYFNFATNEMI
HHHHHHCCCEEEEEHHHHHHHCCCCEEEECCHHHCCCHHHHCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA