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The map label for this gene is bioC [H]

Identifier: 119945613

GI number: 119945613

Start: 2347781

End: 2348620

Strand: Reverse

Name: bioC [H]

Synonym: Ping_1922

Alternate gene names: 119945613

Gene position: 2348620-2347781 (Counterclockwise)

Preceding gene: 119945614

Following gene: 119945612

Centisome position: 51.51

GC content: 35.0

Gene sequence:

>840_bases
ATGGAATATATAGAGCGCTTCATGACAAATAGTGTGAAATTTACAATAGATAAAATCGCAGTCGCTAACTCTTTTTCTAA
AGCGGCATCACATTATGATCAATTTGCACAGTTACAACGTGATATTGGTAATAAGCTTTTTACTTCATTATCTTCATTAG
AAACCTGTTCATTAGAAAACAGGGAGCCGGGCACTTGTTTGGATCTTGGCTGTGGAACCGGCTACTTTAGTGAAAAGTTA
ATTAATGAACAGAAGATTAAATCAATTATTTGCTTTGATCTATCGAGCGGTATGCTTAACTTTTTACAACATAATCGTGA
TTTGTCTCTGTGCTGTATACAGGGGGATATGGACTTTATACCTTTTTCTGATAATCAATTCTCCACTATATTTTCAAACT
TGGCTGTTCAGTGGAGTAGTGATCTTAGTCAGATGCTGATCCAATTAAAACGTATCTTAGTTTCAGGTGGGGAATTAAAT
TTTTCAACTCTATTAGCAGGATCATTAAAAGAGTTAAGTGATGCCTGGTTAACGCTTGATCACTATCCGCATACTAATAC
CTTTTTAACCCTGGCAAATATTCAAGATATGTTAGAAAAAGTGGGTTTCACTAAAGTGACCATTAAAACCGAAACTATTA
CTCTTTATTATAAAAATGTGCTCGATCTGATGCGTGATCTAAAGGGGATAGGGGCTAATCAGGTACATGGACATCACCTG
CATAAATCACAAGGGCGCTCTTTAATCAATAAACTTGAATTGGGTTATGCCAAAGATAAGACCAGATCTGGTTTATTACC
TCTTTCTTATCAAGTTTGTTATATAAAAGCGGTTAAATAA

Upstream 100 bases:

>100_bases
ATGTTGTGCAGTTAGTTAATGCAATATACCGGGTGCTTAATGACAAATAGTATGAAGTTCAATATAAATAAAATACTGGT
AGTTAACTCCTTAACAGTGA

Downstream 100 bases:

>100_bases
TATGAACGTTAGCGTTGTTAACATAATTACTACATTGTTGCATATCAAGTTTGTTATATAAAAGTGGTTAAATAATATAA
AGGTTAGCGTTGTTAACATA

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MEYIERFMTNSVKFTIDKIAVANSFSKAASHYDQFAQLQRDIGNKLFTSLSSLETCSLENREPGTCLDLGCGTGYFSEKL
INEQKIKSIICFDLSSGMLNFLQHNRDLSLCCIQGDMDFIPFSDNQFSTIFSNLAVQWSSDLSQMLIQLKRILVSGGELN
FSTLLAGSLKELSDAWLTLDHYPHTNTFLTLANIQDMLEKVGFTKVTIKTETITLYYKNVLDLMRDLKGIGANQVHGHHL
HKSQGRSLINKLELGYAKDKTRSGLLPLSYQVCYIKAVK

Sequences:

>Translated_279_residues
MEYIERFMTNSVKFTIDKIAVANSFSKAASHYDQFAQLQRDIGNKLFTSLSSLETCSLENREPGTCLDLGCGTGYFSEKL
INEQKIKSIICFDLSSGMLNFLQHNRDLSLCCIQGDMDFIPFSDNQFSTIFSNLAVQWSSDLSQMLIQLKRILVSGGELN
FSTLLAGSLKELSDAWLTLDHYPHTNTFLTLANIQDMLEKVGFTKVTIKTETITLYYKNVLDLMRDLKGIGANQVHGHHL
HKSQGRSLINKLELGYAKDKTRSGLLPLSYQVCYIKAVK
>Mature_279_residues
MEYIERFMTNSVKFTIDKIAVANSFSKAASHYDQFAQLQRDIGNKLFTSLSSLETCSLENREPGTCLDLGCGTGYFSEKL
INEQKIKSIICFDLSSGMLNFLQHNRDLSLCCIQGDMDFIPFSDNQFSTIFSNLAVQWSSDLSQMLIQLKRILVSGGELN
FSTLLAGSLKELSDAWLTLDHYPHTNTFLTLANIQDMLEKVGFTKVTIKTETITLYYKNVLDLMRDLKGIGANQVHGHHL
HKSQGRSLINKLELGYAKDKTRSGLLPLSYQVCYIKAVK

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI40018642, Length=223, Percent_Identity=25.1121076233184, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1786994, Length=258, Percent_Identity=33.7209302325581, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19922210, Length=225, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 31451; Mature: 31451

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIERFMTNSVKFTIDKIAVANSFSKAASHYDQFAQLQRDIGNKLFTSLSSLETCSLEN
CHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
REPGTCLDLGCGTGYFSEKLINEQKIKSIICFDLSSGMLNFLQHNRDLSLCCIQGDMDFI
CCCCCEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
PFSDNQFSTIFSNLAVQWSSDLSQMLIQLKRILVSGGELNFSTLLAGSLKELSDAWLTLD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEE
HYPHTNTFLTLANIQDMLEKVGFTKVTIKTETITLYYKNVLDLMRDLKGIGANQVHGHHL
CCCCCCCEEEHHHHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHH
HKSQGRSLINKLELGYAKDKTRSGLLPLSYQVCYIKAVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MEYIERFMTNSVKFTIDKIAVANSFSKAASHYDQFAQLQRDIGNKLFTSLSSLETCSLEN
CHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
REPGTCLDLGCGTGYFSEKLINEQKIKSIICFDLSSGMLNFLQHNRDLSLCCIQGDMDFI
CCCCCEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEE
PFSDNQFSTIFSNLAVQWSSDLSQMLIQLKRILVSGGELNFSTLLAGSLKELSDAWLTLD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEE
HYPHTNTFLTLANIQDMLEKVGFTKVTIKTETITLYYKNVLDLMRDLKGIGANQVHGHHL
CCCCCCCEEEHHHHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCHH
HKSQGRSLINKLELGYAKDKTRSGLLPLSYQVCYIKAVK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]