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The map label for this gene is fur [H]

Identifier: 119944634

GI number: 119944634

Start: 1094353

End: 1094781

Strand: Reverse

Name: fur [H]

Synonym: Ping_0873

Alternate gene names: 119944634

Gene position: 1094781-1094353 (Counterclockwise)

Preceding gene: 119944635

Following gene: 119944632

Centisome position: 24.01

GC content: 35.9

Gene sequence:

>429_bases
ATGTCGATAGAAAATGATGCATTAAAAGAAGCCGGACTAAAAATAACATCACCACGAGTGAAAATTTTGAGTTTATTACA
ACGACCTGATAATCAACATATTAGTGCGGAAGATCTCTATAAAAAACTACTTGAACAAGGTGATGAAGTAGGTGTAGCGA
CGGTTTATCGTGTATTAAATCAATTTGACGATGCAGGAATAGTCACTCGCCATCATTTTGAGGGTGGAAAATCCGTTTTT
GAGCTTGCCAATCAAGAGCATCATGATCACCTTGTCTGTTTAACCTGTGGAGAGGTTATTGAATTTAATGATGATCTAAT
AGAAAATCAGCAACAGCTCATTGCAGAAAAACACGGAATTAAGTTAACTAATCACAGCCTTTATCTGTTTGGTGAAGCAA
TTGATGGTAAATGCAAGCATAAAACATAG

Upstream 100 bases:

>100_bases
GCTGCTCGCGTAAAAGAATGGTCAAAACAGGTTTATGATGAAATGTGTCTTGCTGAACTTGCAGATTAATTATTCGCAGC
GAAAATCCTAGGAATCCAGC

Downstream 100 bases:

>100_bases
CCAATAGTTATCATCTGAAAGCCTCAGTTATCATATTAAAAGCCTCGTTTAGCCTATTGTAAACGGGGCTTTTTTTTATA
CATAACAAGCTAGCGTATGT

Product: ferric uptake regulator, Fur family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSIENDALKEAGLKITSPRVKILSLLQRPDNQHISAEDLYKKLLEQGDEVGVATVYRVLNQFDDAGIVTRHHFEGGKSVF
ELANQEHHDHLVCLTCGEVIEFNDDLIENQQQLIAEKHGIKLTNHSLYLFGEAIDGKCKHKT

Sequences:

>Translated_142_residues
MSIENDALKEAGLKITSPRVKILSLLQRPDNQHISAEDLYKKLLEQGDEVGVATVYRVLNQFDDAGIVTRHHFEGGKSVF
ELANQEHHDHLVCLTCGEVIEFNDDLIENQQQLIAEKHGIKLTNHSLYLFGEAIDGKCKHKT
>Mature_141_residues
SIENDALKEAGLKITSPRVKILSLLQRPDNQHISAEDLYKKLLEQGDEVGVATVYRVLNQFDDAGIVTRHHFEGGKSVFE
LANQEHHDHLVCLTCGEVIEFNDDLIENQQQLIAEKHGIKLTNHSLYLFGEAIDGKCKHKT

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=139, Percent_Identity=69.7841726618705, Blast_Score=211, Evalue=1e-56,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16016; Mature: 15885

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIENDALKEAGLKITSPRVKILSLLQRPDNQHISAEDLYKKLLEQGDEVGVATVYRVLN
CCCCHHHHHHCCCEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
QFDDAGIVTRHHFEGGKSVFELANQEHHDHLVCLTCGEVIEFNDDLIENQQQLIAEKHGI
HCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHCCC
KLTNHSLYLFGEAIDGKCKHKT
EEECCEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SIENDALKEAGLKITSPRVKILSLLQRPDNQHISAEDLYKKLLEQGDEVGVATVYRVLN
CCCHHHHHHCCCEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHH
QFDDAGIVTRHHFEGGKSVFELANQEHHDHLVCLTCGEVIEFNDDLIENQQQLIAEKHGI
HCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHCCC
KLTNHSLYLFGEAIDGKCKHKT
EEECCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9055816 [H]