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The map label for this gene is 119944477

Identifier: 119944477

GI number: 119944477

Start: 897917

End: 898225

Strand: Direct

Name: 119944477

Synonym: Ping_0706

Alternate gene names: NA

Gene position: 897917-898225 (Clockwise)

Preceding gene: 119944476

Following gene: 119944478

Centisome position: 19.69

GC content: 31.07

Gene sequence:

>309_bases
ATGGATTTGAAAAAATTGAGTGGTAGTGAGTTATTGATTGAGCTTGAAAAACTGAATTGTGATTTAGCTATCCCCTGGAA
AATTGAGGATGAAAAATTAAGTAAAACCTTTAAGTTTAAAAACTTTATGCAGGCATTTGCATTTATGACACAAAGTGCTC
TTTATGCGGAAAAGAAAAATCATCACCCCGAATGGTTTAATATCTATAACAAAGTTGTTATTCAGTTAACCACTCATGAT
GTTGCGGGAATAAGCTTTAAAGATTTTGATTTGGCTAAAAAAATGGAATCATTTATCCCGCATTTTTAA

Upstream 100 bases:

>100_bases
TTATCGCCTTCCCACCTTTTAGCTTTTTAGCCTTTTCGCGTTATATTAGAAGGGGTGCTGGCACCCTTGAAATTATCTGG
CTTTGCAAAGGAGAGAATAA

Downstream 100 bases:

>100_bases
ACTGAGCGTTACAGCATTCGCGGTTGTTAGGCACTGCTGCTTTATAGATACTCGTCCTTCATCTGCTGGCGAGTATTACT
CTATGATACTATTTCCCTCT

Product: transcriptional coactivator/pterin dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MDLKKLSGSELLIELEKLNCDLAIPWKIEDEKLSKTFKFKNFMQAFAFMTQSALYAEKKNHHPEWFNIYNKVVIQLTTHD
VAGISFKDFDLAKKMESFIPHF

Sequences:

>Translated_102_residues
MDLKKLSGSELLIELEKLNCDLAIPWKIEDEKLSKTFKFKNFMQAFAFMTQSALYAEKKNHHPEWFNIYNKVVIQLTTHD
VAGISFKDFDLAKKMESFIPHF
>Mature_102_residues
MDLKKLSGSELLIELEKLNCDLAIPWKIEDEKLSKTFKFKNFMQAFAFMTQSALYAEKKNHHPEWFNIYNKVVIQLTTHD
VAGISFKDFDLAKKMESFIPHF

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=68, Percent_Identity=57.3529411764706, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI4557831, Length=62, Percent_Identity=59.6774193548387, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533705, Length=86, Percent_Identity=47.6744186046512, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549100, Length=84, Percent_Identity=50, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_PSYIN (A1SSU3)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942157.1
- ProteinModelPortal:   A1SSU3
- SMR:   A1SSU3
- STRING:   A1SSU3
- GeneID:   4627037
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0706
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   HAFGFMT
- ProtClustDB:   CLSK962478
- BioCyc:   PING357804:PING_0706-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 12002; Mature: 12002

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKKLSGSELLIELEKLNCDLAIPWKIEDEKLSKTFKFKNFMQAFAFMTQSALYAEKKN
CCCCCCCCCCEEEEEECCCCCEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HHPEWFNIYNKVVIQLTTHDVAGISFKDFDLAKKMESFIPHF
CCCHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLKKLSGSELLIELEKLNCDLAIPWKIEDEKLSKTFKFKNFMQAFAFMTQSALYAEKKN
CCCCCCCCCCEEEEEECCCCCEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HHPEWFNIYNKVVIQLTTHDVAGISFKDFDLAKKMESFIPHF
CCCHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA