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The map label for this gene is cvrA [H]

Identifier: 119944478

GI number: 119944478

Start: 898650

End: 900605

Strand: Direct

Name: cvrA [H]

Synonym: Ping_0707

Alternate gene names: 119944478

Gene position: 898650-900605 (Clockwise)

Preceding gene: 119944477

Following gene: 119944479

Centisome position: 19.71

GC content: 41.16

Gene sequence:

>1956_bases
ATGGTTGACAAAATTACCGCTATGCTAGGCTTGGTGGGCATTTTATCTTTATTGTGTCAGTGGATTGGTTGGAAAATTCG
ATTACCAGCTATATTACCTCTGTTGATCTGTGGTTTACTTATTGGTCCCGGATTGAATATTCTCAAACCTGATGAGCTAT
TTGGCGAACTGCTCTTTCCTATTATCTCTTTAGGGGTTGCGATTATTCTTTTTGAAGGGGCTTTAACGCTCAACTTTAAA
GAGCTTAAAAATCACGGGCGAATGGTGACCCACCTCGTTTCTCTCGGTACGCTTATTACATGGGGATGTATTGCCAGCGC
CACACATATTATACTCGAATTTCAATGGTCGATGGCTATTCTGTTTGGTGCGCTGGTGGTGGTCACCGGGCCTACGGTGA
TAGTCCCTATGCTACGTAGTATCAAACCCAAAACAGAATTAGCCAGTATTTTACGTTGGGAGGGGATCCTTATTGATCCC
GTTGGCGCAGTGCTTGCGGTTCTGGTTTTTGAGTACATTTCATTCACTTCTGATCCAGCGGTACATATACTTTCAGCTTT
GGCCACAACCTTAGTAATAGGCTTGGGTTTTGGCCTGATCAGTGGTTATTATTTGGGCTACCTGCTAAGAAATAATTTGT
TACCTCATTATTTAAAGAATACCGCTGTGGTCACTATTATGCTGGGTGTATTTGTCAGCGCTAATCTCATGCAGGAAGAG
TCTGGTTTACTGACCGTTACTGTTATGGGGATTGTATTGGCGAATATGCGTGGTGTTGGCGTTTCCGATATTCTAGAGTT
TAAAGAAACATTAACGGTATTAGTGATTTCGGTCTTATTTATTCTACTCGCCGCTCGTGTCGATTCCGAGGCGCTACTGA
GTTTAGGTTGGCAAGGTCTTGTTCTTTTATTGGTGGTGCTGTTTATTGCCCGCCCCTTAAGTGTTTGGTGTTGCGGACTG
GGCACATCCTTAACTAAACAGGATAAATGGTTTTTAAGTTGGATGGCGCCGCGAGGCATTGTCGCAGCAGCGGTATCATC
CCTGTTTGCTATTAAACTGGAAAAAATAGGGGTAGAAGGAGCCGAATTAATTGTCCCTTTAGTCTTTCTGATTATTATTG
GAACCGTGGTTATTCAAAGTCTGACAGCAGGGCCTTGGGCAAAATTTTTACGCGTCAACAAAGAAAAATCACAGGGACTG
CTTATTTTTGGCGCTTCCCGTTTTTCGAGAGAGTTAGCGGCCGTTTTAATGTCAAAGAATATCAATATGCTGCTCGCTGA
TAATAATTGGGATAATATCAGACTTGCGCGCATGATGAATATTCCTGTCTATTATGGCAACCCGGCATCGGCGCATGCAC
TTAATTTTTTAGATATGACCGGCATAGGGCGATTATTAGTGCTGTCTCCCTACACAGAGCTTAATCCTCTGGTGGTTTTC
CAGTATCAAGATTTATTGGGTAAAGAAAATGTATATGGGTTAGATAACGGGGATGTAAAAAAACCCAGGCACCAATTGTC
AGAAACATACCGGCAACGGTTATGTTTATTTGGTAAAACAGTTTCCTACGCTAAATTAGTCAGTTTAATATATCAGGGTG
CTGTGGTTAAAAGTACCAATCTTACGGAAAATTTTACTTTTACCAATTTCCGTACCTGTTATGGTGATTCTGCACTGCCA
CTTGTGTACATAAAAAATGAAAAAGTATTTATATATACCGCATCAGAGTCAATACCGAGCAGTGACATTGAATTGATTAG
TTTATTGCCGGTATCAGCTCAACATCTTGGTACAAAATGGGCTGAAAAACAGCAGCAGGTCTTACAAGAAGCGCGAGAAC
AGGAGTCTTTAAGCGCCCAAAGTCCTAAGAGTGATAAGAATCCAAATCATTATGAAAAAATAAAAACATTGATAACAAAA
AGCATTAATCACAACGGCAAAGCAAAAAAAACTTAA

Upstream 100 bases:

>100_bases
TTTTACAGATATGATTTTTAAAAAAACAAGCGCACCAATGTAGTTCTATGTCGACTCAGGAAGTTACCTTTTTATATTGA
AAAAGTTTTAGGGGAAATTT

Downstream 100 bases:

>100_bases
TTTCTTATTTGCGGTTCAGGATCTGCATTACGCAAAATAAATGAGCGAAGCAAGTCGCTGGAAACGACATTCAGGGGCTG
CGTATAATGCTATCCCACCG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MVDKITAMLGLVGILSLLCQWIGWKIRLPAILPLLICGLLIGPGLNILKPDELFGELLFPIISLGVAIILFEGALTLNFK
ELKNHGRMVTHLVSLGTLITWGCIASATHIILEFQWSMAILFGALVVVTGPTVIVPMLRSIKPKTELASILRWEGILIDP
VGAVLAVLVFEYISFTSDPAVHILSALATTLVIGLGFGLISGYYLGYLLRNNLLPHYLKNTAVVTIMLGVFVSANLMQEE
SGLLTVTVMGIVLANMRGVGVSDILEFKETLTVLVISVLFILLAARVDSEALLSLGWQGLVLLLVVLFIARPLSVWCCGL
GTSLTKQDKWFLSWMAPRGIVAAAVSSLFAIKLEKIGVEGAELIVPLVFLIIIGTVVIQSLTAGPWAKFLRVNKEKSQGL
LIFGASRFSRELAAVLMSKNINMLLADNNWDNIRLARMMNIPVYYGNPASAHALNFLDMTGIGRLLVLSPYTELNPLVVF
QYQDLLGKENVYGLDNGDVKKPRHQLSETYRQRLCLFGKTVSYAKLVSLIYQGAVVKSTNLTENFTFTNFRTCYGDSALP
LVYIKNEKVFIYTASESIPSSDIELISLLPVSAQHLGTKWAEKQQQVLQEAREQESLSAQSPKSDKNPNHYEKIKTLITK
SINHNGKAKKT

Sequences:

>Translated_651_residues
MVDKITAMLGLVGILSLLCQWIGWKIRLPAILPLLICGLLIGPGLNILKPDELFGELLFPIISLGVAIILFEGALTLNFK
ELKNHGRMVTHLVSLGTLITWGCIASATHIILEFQWSMAILFGALVVVTGPTVIVPMLRSIKPKTELASILRWEGILIDP
VGAVLAVLVFEYISFTSDPAVHILSALATTLVIGLGFGLISGYYLGYLLRNNLLPHYLKNTAVVTIMLGVFVSANLMQEE
SGLLTVTVMGIVLANMRGVGVSDILEFKETLTVLVISVLFILLAARVDSEALLSLGWQGLVLLLVVLFIARPLSVWCCGL
GTSLTKQDKWFLSWMAPRGIVAAAVSSLFAIKLEKIGVEGAELIVPLVFLIIIGTVVIQSLTAGPWAKFLRVNKEKSQGL
LIFGASRFSRELAAVLMSKNINMLLADNNWDNIRLARMMNIPVYYGNPASAHALNFLDMTGIGRLLVLSPYTELNPLVVF
QYQDLLGKENVYGLDNGDVKKPRHQLSETYRQRLCLFGKTVSYAKLVSLIYQGAVVKSTNLTENFTFTNFRTCYGDSALP
LVYIKNEKVFIYTASESIPSSDIELISLLPVSAQHLGTKWAEKQQQVLQEAREQESLSAQSPKSDKNPNHYEKIKTLITK
SINHNGKAKKT
>Mature_651_residues
MVDKITAMLGLVGILSLLCQWIGWKIRLPAILPLLICGLLIGPGLNILKPDELFGELLFPIISLGVAIILFEGALTLNFK
ELKNHGRMVTHLVSLGTLITWGCIASATHIILEFQWSMAILFGALVVVTGPTVIVPMLRSIKPKTELASILRWEGILIDP
VGAVLAVLVFEYISFTSDPAVHILSALATTLVIGLGFGLISGYYLGYLLRNNLLPHYLKNTAVVTIMLGVFVSANLMQEE
SGLLTVTVMGIVLANMRGVGVSDILEFKETLTVLVISVLFILLAARVDSEALLSLGWQGLVLLLVVLFIARPLSVWCCGL
GTSLTKQDKWFLSWMAPRGIVAAAVSSLFAIKLEKIGVEGAELIVPLVFLIIIGTVVIQSLTAGPWAKFLRVNKEKSQGL
LIFGASRFSRELAAVLMSKNINMLLADNNWDNIRLARMMNIPVYYGNPASAHALNFLDMTGIGRLLVLSPYTELNPLVVF
QYQDLLGKENVYGLDNGDVKKPRHQLSETYRQRLCLFGKTVSYAKLVSLIYQGAVVKSTNLTENFTFTNFRTCYGDSALP
LVYIKNEKVFIYTASESIPSSDIELISLLPVSAQHLGTKWAEKQQQVLQEAREQESLSAQSPKSDKNPNHYEKIKTLITK
SINHNGKAKKT

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 71521; Mature: 71521

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDKITAMLGLVGILSLLCQWIGWKIRLPAILPLLICGLLIGPGLNILKPDELFGELLFP
CCHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
IISLGVAIILFEGALTLNFKELKNHGRMVTHLVSLGTLITWGCIASATHIILEFQWSMAI
HHHHHHHHHHHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHH
LFGALVVVTGPTVIVPMLRSIKPKTELASILRWEGILIDPVGAVLAVLVFEYISFTSDPA
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCCHH
VHILSALATTLVIGLGFGLISGYYLGYLLRNNLLPHYLKNTAVVTIMLGVFVSANLMQEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SGLLTVTVMGIVLANMRGVGVSDILEFKETLTVLVISVLFILLAARVDSEALLSLGWQGL
CCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHH
VLLLVVLFIARPLSVWCCGLGTSLTKQDKWFLSWMAPRGIVAAAVSSLFAIKLEKIGVEG
HHHHHHHHHHCHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
AELIVPLVFLIIIGTVVIQSLTAGPWAKFLRVNKEKSQGLLIFGASRFSRELAAVLMSKN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCC
INMLLADNNWDNIRLARMMNIPVYYGNPASAHALNFLDMTGIGRLLVLSPYTELNPLVVF
CCEEEECCCCCCEEEEEEEECCEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
QYQDLLGKENVYGLDNGDVKKPRHQLSETYRQRLCLFGKTVSYAKLVSLIYQGAVVKSTN
EEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCC
LTENFTFTNFRTCYGDSALPLVYIKNEKVFIYTASESIPSSDIELISLLPVSAQHLGTKW
CCCCCCCCCCHHHCCCCCCEEEEEECCEEEEEECCCCCCCCCCHHHHCCCCCHHHHCHHH
AEKQQQVLQEAREQESLSAQSPKSDKNPNHYEKIKTLITKSINHNGKAKKT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVDKITAMLGLVGILSLLCQWIGWKIRLPAILPLLICGLLIGPGLNILKPDELFGELLFP
CCHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
IISLGVAIILFEGALTLNFKELKNHGRMVTHLVSLGTLITWGCIASATHIILEFQWSMAI
HHHHHHHHHHHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHH
LFGALVVVTGPTVIVPMLRSIKPKTELASILRWEGILIDPVGAVLAVLVFEYISFTSDPA
HHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHCCCCHH
VHILSALATTLVIGLGFGLISGYYLGYLLRNNLLPHYLKNTAVVTIMLGVFVSANLMQEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
SGLLTVTVMGIVLANMRGVGVSDILEFKETLTVLVISVLFILLAARVDSEALLSLGWQGL
CCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHH
VLLLVVLFIARPLSVWCCGLGTSLTKQDKWFLSWMAPRGIVAAAVSSLFAIKLEKIGVEG
HHHHHHHHHHCHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
AELIVPLVFLIIIGTVVIQSLTAGPWAKFLRVNKEKSQGLLIFGASRFSRELAAVLMSKN
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCC
INMLLADNNWDNIRLARMMNIPVYYGNPASAHALNFLDMTGIGRLLVLSPYTELNPLVVF
CCEEEECCCCCCEEEEEEEECCEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
QYQDLLGKENVYGLDNGDVKKPRHQLSETYRQRLCLFGKTVSYAKLVSLIYQGAVVKSTN
EEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCC
LTENFTFTNFRTCYGDSALPLVYIKNEKVFIYTASESIPSSDIELISLLPVSAQHLGTKW
CCCCCCCCCCHHHCCCCCCEEEEEECCEEEEEECCCCCCCCCCHHHHCCCCCHHHHCHHH
AEKQQQVLQEAREQESLSAQSPKSDKNPNHYEKIKTLITKSINHNGKAKKT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]