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The map label for this gene is int [H]

Identifier: 119900014

GI number: 119900014

Start: 4079327

End: 4079527

Strand: Direct

Name: int [H]

Synonym: azo3725

Alternate gene names: 119900014

Gene position: 4079327-4079527 (Clockwise)

Preceding gene: 119900013

Following gene: 119900018

Centisome position: 93.22

GC content: 65.17

Gene sequence:

>201_bases
GTGAAAAGGGCCGGCATCGCCCGTCATGTCACGGTGCACACGCTGCGCCATTCGGTCGCCACCCACCTGCTCGAAGGCGG
CTACGACATCCGCACCGTGCAGGAACTGCTCGGCCACGCGGACGTGTCGACCACGATGATTTACACCCACGTGCTCAACA
AGGGCGGTCGCGGGGTGGTGTCGCCCATCGACCGCCTTTGA

Upstream 100 bases:

>100_bases
GGTCTGGCCGTCGCCGACGCTCGCGGTCGATCCGCGCTCGGGCGTGCCCAGGCGGCATCACCTGTACGAAGAGCGCCTGC
AGCGTGCGCTGCGCAATGCA

Downstream 100 bases:

>100_bases
GCCGCCTTACAGCAGCGGCGCCAGCCAGCGCGCCGCTGCTTCTTCGGTGAGGCCGGTGCGTTGCGCCCAGTCGGTGACCT
GATCCCGGCCGATCTTGCTG

Product: integrase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 66; Mature: 66

Protein sequence:

>66_residues
MKRAGIARHVTVHTLRHSVATHLLEGGYDIRTVQELLGHADVSTTMIYTHVLNKGGRGVVSPIDRL

Sequences:

>Translated_66_residues
MKRAGIARHVTVHTLRHSVATHLLEGGYDIRTVQELLGHADVSTTMIYTHVLNKGGRGVVSPIDRL
>Mature_66_residues
MKRAGIARHVTVHTLRHSVATHLLEGGYDIRTVQELLGHADVSTTMIYTHVLNKGGRGVVSPIDRL

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=49, Percent_Identity=61.2244897959184, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1789261, Length=49, Percent_Identity=61.2244897959184, Blast_Score=59, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 7257; Mature: 7257

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAGIARHVTVHTLRHSVATHLLEGGYDIRTVQELLGHADVSTTMIYTHVLNKGGRGVV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
SPIDRL
CCCCCC
>Mature Secondary Structure
MKRAGIARHVTVHTLRHSVATHLLEGGYDIRTVQELLGHADVSTTMIYTHVLNKGGRGVV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCC
SPIDRL
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]