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The map label for this gene is int [H]

Identifier: 119900013

GI number: 119900013

Start: 4078566

End: 4079330

Strand: Direct

Name: int [H]

Synonym: azo3724

Alternate gene names: 119900013

Gene position: 4078566-4079330 (Clockwise)

Preceding gene: 119900010

Following gene: 119900014

Centisome position: 93.2

GC content: 63.66

Gene sequence:

>765_bases
ATGACGGCAGTCCGGCTGCTCGACCAGGTTCGGGCACGCATTCGGTATAAGCACTACAGCTTAGGAACCGAACAGCAGTA
TGTCTATTGGGTGCGCACCTTCCTCCGCTTCCATGGCGTGCGCCATCCTCGCGAGATGGGTGCGACCGAGGTCGAGCAGT
TCCTGAGCTGGCTTGCGACCGATCGGAAGGTTGCGGTCTCCACCCACAAGCAGGCACTGTCCGCGCTTCTGTTCCTCTAT
CGCAACGTGTTGGGCGTCGATCTTCCTTGGCTATCTGAGTTCGAGCGACCGAAAACGCCCGTTCGTCTGCCGTCGGTCCT
GTCGGGCGAAGAGGTAAGCGCGCTGCTGGATGCGATGGAGGGCTCCAACGCCGATCTGGCGCGCCTCGTCTACGGCACAG
GGATGCGCCTGAGGGAAGCGCTACGGCTGCGAGTGAAGGATGTCGACTTTCAACGCAGACTGATCGTGGTGCGCGAAGGC
AAGGGCAACAAGGACCGCATCGTGATGTTGCCCCACCGGTGCAGCAACGCCTTGCGCGAGCAATTGCACAGGGCGTACCT
GCTGTGGGCGCAGGATCGGGCGGACGGGACGCCCGGTGGGAGATGTCCGAGTCCCTCGCGCACAAATACCCGCGTGCAGC
GGAATCCTGGCCATGGTTCTGGGTCTGGCCGTCGCCGACGCTCGCGGTCGATCCGCGCTCGGGCGTGCCCAGGCGGCATC
ACCTGTACGAAGAGCGCCTGCAGCGTGCGCTGCGCAATGCAGTGA

Upstream 100 bases:

>100_bases
GACTGATGACGATGCCATTTCCTGAATATGCTGTATTTATGAACAGTCATAACTCAACCGACAACCCCCCCAGACCTCGG
AGCGAACCACCTGCTCCCCG

Downstream 100 bases:

>100_bases
AAAGGGCCGGCATCGCCCGTCATGTCACGGTGCACACGCTGCGCCATTCGGTCGCCACCCACCTGCTCGAAGGCGGCTAC
GACATCCGCACCGTGCAGGA

Product: truncated integrase/recombinase

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTAVRLLDQVRARIRYKHYSLGTEQQYVYWVRTFLRFHGVRHPREMGATEVEQFLSWLATDRKVAVSTHKQALSALLFLY
RNVLGVDLPWLSEFERPKTPVRLPSVLSGEEVSALLDAMEGSNADLARLVYGTGMRLREALRLRVKDVDFQRRLIVVREG
KGNKDRIVMLPHRCSNALREQLHRAYLLWAQDRADGTPGGRCPSPSRTNTRVQRNPGHGSGSGRRRRSRSIRARACPGGI
TCTKSACSVRCAMQ

Sequences:

>Translated_254_residues
MTAVRLLDQVRARIRYKHYSLGTEQQYVYWVRTFLRFHGVRHPREMGATEVEQFLSWLATDRKVAVSTHKQALSALLFLY
RNVLGVDLPWLSEFERPKTPVRLPSVLSGEEVSALLDAMEGSNADLARLVYGTGMRLREALRLRVKDVDFQRRLIVVREG
KGNKDRIVMLPHRCSNALREQLHRAYLLWAQDRADGTPGGRCPSPSRTNTRVQRNPGHGSGSGRRRRSRSIRARACPGGI
TCTKSACSVRCAMQ
>Mature_253_residues
TAVRLLDQVRARIRYKHYSLGTEQQYVYWVRTFLRFHGVRHPREMGATEVEQFLSWLATDRKVAVSTHKQALSALLFLYR
NVLGVDLPWLSEFERPKTPVRLPSVLSGEEVSALLDAMEGSNADLARLVYGTGMRLREALRLRVKDVDFQRRLIVVREGK
GNKDRIVMLPHRCSNALREQLHRAYLLWAQDRADGTPGGRCPSPSRTNTRVQRNPGHGSGSGRRRRSRSIRARACPGGIT
CTKSACSVRCAMQ

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 28897; Mature: 28766

Theoretical pI: Translated: 11.42; Mature: 11.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVRLLDQVRARIRYKHYSLGTEQQYVYWVRTFLRFHGVRHPREMGATEVEQFLSWLAT
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHC
DRKVAVSTHKQALSALLFLYRNVLGVDLPWLSEFERPKTPVRLPSVLSGEEVSALLDAME
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHC
GSNADLARLVYGTGMRLREALRLRVKDVDFQRRLIVVREGKGNKDRIVMLPHRCSNALRE
CCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHH
QLHRAYLLWAQDRADGTPGGRCPSPSRTNTRVQRNPGHGSGSGRRRRSRSIRARACPGGI
HHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHCCHHCCCCCCC
TCTKSACSVRCAMQ
EECCHHHCEEECCC
>Mature Secondary Structure 
TAVRLLDQVRARIRYKHYSLGTEQQYVYWVRTFLRFHGVRHPREMGATEVEQFLSWLAT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHC
DRKVAVSTHKQALSALLFLYRNVLGVDLPWLSEFERPKTPVRLPSVLSGEEVSALLDAME
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHC
GSNADLARLVYGTGMRLREALRLRVKDVDFQRRLIVVREGKGNKDRIVMLPHRCSNALRE
CCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHH
QLHRAYLLWAQDRADGTPGGRCPSPSRTNTRVQRNPGHGSGSGRRRRSRSIRARACPGGI
HHHHHHHEEECCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHCCHHCCCCCCC
TCTKSACSVRCAMQ
EECCHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]