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The map label for this gene is visC [H]

Identifier: 119775854

GI number: 119775854

Start: 3256945

End: 3258126

Strand: Reverse

Name: visC [H]

Synonym: Sama_2722

Alternate gene names: 119775854

Gene position: 3258126-3256945 (Counterclockwise)

Preceding gene: 119775855

Following gene: 119775853

Centisome position: 75.66

GC content: 58.71

Gene sequence:

>1182_bases
ATGATGACAACCCAAAGCTGTGATGTGGCCATTGTAGGTGGCGGCATGGTGGGATTGGCAACCGCCATCGGCCTTGCCGA
GGCCGGGCTTAAGGTGACAGTCCTGGATGCGGGCAGCCAGAGTGCTGTTGCAGGCGAGCCGCGTCTTCGGGTCAGCGCCA
TCAACCGCGCCAGCGAAGATTTGCTCAAATCTCTGGGCGCCTGGCCGCTGATGGACAGCCAGCGCACCGCCTCCTATGGC
CGTATGCAGGTGTGGGACAAAGACGGCATGGGCAAAATTGGTTTTGATGCCAATGAACTGGGCGAATCAAGCCTTGGCAC
CATCATCGAAAACGACAATATTGCCGCCGCGCTGGCAAAACGTGCCGGAGAGTTCGATAACCTGGATTACCGGGAAGGTG
TGCGTTTAAGCCGCCTTGCCTTTGGTGAAAAGGAAGCCTGGCTGACCCTGGAAGAGGGCGACATGCTCTCGGCTGCGCTG
GTGATTGCCGCCGACGGCGCAAACAGTTGGGTGCGCAGCCAGTGCAATATTCCGCTGACGTTCTGGGACTATGGCCACAC
CGCCATTGTTGCCACCATAGAAACCGCCGAGCCCCACGAGAGCTGTGCCCGACAGGTGTTTTTGCCTGACGGCCCGCTGG
CGTTTTTGCCGCTGTTTCAGGCAAATCTTTGCTCCATCGTTTGGTCGGTAACCGAGCCTCGGGCGCAGGAACTGCTGGCG
ATGGATGATGAAAATTTTTCAAAGTCGCTTACCGCCGCCTTCGATGCCCGCCTTGGTCTGTGCCACGTAAAGAGTGAGCG
TATCGGCTTTAACCTGCGCATGCGCTATGCCCGCCATTTTGCCCGTCACCGGCTGCTGCTGGCGGGGGATGCGGCCCACA
CCATACACCCGTTGGCGGGGCAGGGCGTTAACCTGGGTTTTCAGGACGCCGCCGCCATTATCGAGACCATTGGTCGCCTG
AAAGCCGAGGGCAAAGATATAGGTGACTACCGTCTGCTCCGGCCGCTGGAGCGTGAGCGCAAGGCCGCCGCCCAGGAAAT
GATTGCTACCATGGAAGGCTTCAAACGCCTCTTTGAAGGCAGCAACCCCATCAAGCAGGCCGTGCGGGATCTGGGATTGA
ACCTGGTGGATAAGTTGCCTGGACTGAAAACAGTGTTCATCAAACAGGCCATGGGCAGATAA

Upstream 100 bases:

>100_bases
GTCCGCCGCTCAAGGCGCCGCTTGCAAGCCGGGCCATGGGCTGGCGCCGTGGTGTCCGCCTGACGCCCAACCTGTAACTA
TTTCGTCCGAGGACTGACAG

Downstream 100 bases:

>100_bases
GCAAACAGTCTCTGTGAAATATTTGATAACAGCGGCTGGCCCAACAGCCGTTAAAGGTGATTTTTGCAGCAAATATCAAA
CAATTGGCGGCGAAAAATTG

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MMTTQSCDVAIVGGGMVGLATAIGLAEAGLKVTVLDAGSQSAVAGEPRLRVSAINRASEDLLKSLGAWPLMDSQRTASYG
RMQVWDKDGMGKIGFDANELGESSLGTIIENDNIAAALAKRAGEFDNLDYREGVRLSRLAFGEKEAWLTLEEGDMLSAAL
VIAADGANSWVRSQCNIPLTFWDYGHTAIVATIETAEPHESCARQVFLPDGPLAFLPLFQANLCSIVWSVTEPRAQELLA
MDDENFSKSLTAAFDARLGLCHVKSERIGFNLRMRYARHFARHRLLLAGDAAHTIHPLAGQGVNLGFQDAAAIIETIGRL
KAEGKDIGDYRLLRPLERERKAAAQEMIATMEGFKRLFEGSNPIKQAVRDLGLNLVDKLPGLKTVFIKQAMGR

Sequences:

>Translated_393_residues
MMTTQSCDVAIVGGGMVGLATAIGLAEAGLKVTVLDAGSQSAVAGEPRLRVSAINRASEDLLKSLGAWPLMDSQRTASYG
RMQVWDKDGMGKIGFDANELGESSLGTIIENDNIAAALAKRAGEFDNLDYREGVRLSRLAFGEKEAWLTLEEGDMLSAAL
VIAADGANSWVRSQCNIPLTFWDYGHTAIVATIETAEPHESCARQVFLPDGPLAFLPLFQANLCSIVWSVTEPRAQELLA
MDDENFSKSLTAAFDARLGLCHVKSERIGFNLRMRYARHFARHRLLLAGDAAHTIHPLAGQGVNLGFQDAAAIIETIGRL
KAEGKDIGDYRLLRPLERERKAAAQEMIATMEGFKRLFEGSNPIKQAVRDLGLNLVDKLPGLKTVFIKQAMGR
>Mature_393_residues
MMTTQSCDVAIVGGGMVGLATAIGLAEAGLKVTVLDAGSQSAVAGEPRLRVSAINRASEDLLKSLGAWPLMDSQRTASYG
RMQVWDKDGMGKIGFDANELGESSLGTIIENDNIAAALAKRAGEFDNLDYREGVRLSRLAFGEKEAWLTLEEGDMLSAAL
VIAADGANSWVRSQCNIPLTFWDYGHTAIVATIETAEPHESCARQVFLPDGPLAFLPLFQANLCSIVWSVTEPRAQELLA
MDDENFSKSLTAAFDARLGLCHVKSERIGFNLRMRYARHFARHRLLLAGDAAHTIHPLAGQGVNLGFQDAAAIIETIGRL
KAEGKDIGDYRLLRPLERERKAAAQEMIATMEGFKRLFEGSNPIKQAVRDLGLNLVDKLPGLKTVFIKQAMGR

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=399, Percent_Identity=32.5814536340852, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI32967307, Length=343, Percent_Identity=32.3615160349854, Blast_Score=151, Evalue=9e-37,
Organism=Escherichia coli, GI1789273, Length=390, Percent_Identity=55.3846153846154, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1786883, Length=394, Percent_Identity=35.7868020304569, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1789274, Length=390, Percent_Identity=29.2307692307692, Blast_Score=161, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI25146631, Length=430, Percent_Identity=31.1627906976744, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321694, Length=451, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI19920760, Length=436, Percent_Identity=33.4862385321101, Blast_Score=176, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42657; Mature: 42657

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTQSCDVAIVGGGMVGLATAIGLAEAGLKVTVLDAGSQSAVAGEPRLRVSAINRASED
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHH
LLKSLGAWPLMDSQRTASYGRMQVWDKDGMGKIGFDANELGESSLGTIIENDNIAAALAK
HHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCCCCEEECCCHHHHHHH
RAGEFDNLDYREGVRLSRLAFGEKEAWLTLEEGDMLSAALVIAADGANSWVRSQCNIPLT
HCCCCCCCCHHCCCEEHHHHCCCCCEEEEECCCCCEEEEEEEEECCCCHHHHCCCCCEEE
FWDYGHTAIVATIETAEPHESCARQVFLPDGPLAFLPLFQANLCSIVWSVTEPRAQELLA
EECCCCEEEEEEEECCCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
MDDENFSKSLTAAFDARLGLCHVKSERIGFNLRMRYARHFARHRLLLAGDAAHTIHPLAG
CCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCHHHCCCCCC
QGVNLGFQDAAAIIETIGRLKAEGKDIGDYRLLRPLERERKAAAQEMIATMEGFKRLFEG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SNPIKQAVRDLGLNLVDKLPGLKTVFIKQAMGR
CCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MMTTQSCDVAIVGGGMVGLATAIGLAEAGLKVTVLDAGSQSAVAGEPRLRVSAINRASED
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEHHHHHHHHH
LLKSLGAWPLMDSQRTASYGRMQVWDKDGMGKIGFDANELGESSLGTIIENDNIAAALAK
HHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCCCCEEECCCHHHHHHH
RAGEFDNLDYREGVRLSRLAFGEKEAWLTLEEGDMLSAALVIAADGANSWVRSQCNIPLT
HCCCCCCCCHHCCCEEHHHHCCCCCEEEEECCCCCEEEEEEEEECCCCHHHHCCCCCEEE
FWDYGHTAIVATIETAEPHESCARQVFLPDGPLAFLPLFQANLCSIVWSVTEPRAQELLA
EECCCCEEEEEEEECCCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
MDDENFSKSLTAAFDARLGLCHVKSERIGFNLRMRYARHFARHRLLLAGDAAHTIHPLAG
CCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHCEEEEECCCHHHCCCCCC
QGVNLGFQDAAAIIETIGRLKAEGKDIGDYRLLRPLERERKAAAQEMIATMEGFKRLFEG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SNPIKQAVRDLGLNLVDKLPGLKTVFIKQAMGR
CCHHHHHHHHCCCHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]