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The map label for this gene is ygjG [C]

Identifier: 119775775

GI number: 119775775

Start: 3166428

End: 3167810

Strand: Reverse

Name: ygjG [C]

Synonym: Sama_2643

Alternate gene names: 119775775

Gene position: 3167810-3166428 (Counterclockwise)

Preceding gene: 119775776

Following gene: 119775774

Centisome position: 73.56

GC content: 54.09

Gene sequence:

>1383_bases
ATGCAACAACAACAGCAAGATACCATCAGCGCACTGCAAGCCATGGATGCCGCACATCATCTGCATCCTTTTACCGACAG
TGCCGATTTGGCCAAACGCGGCACCCGCGTCATCGAGCGGGCCGAAGGTGTATACATCTGGGATGCCAAAGGTAATAAGC
TGCTCGATGCCATGGCTGGACTCTGGTGTGTCAACGTGGGCTATGGCCGAAAGTCCATCGCCGATGCTGCTTACGCTCAG
CTGCAAACCCTCCCTTTTTACAATAATTTCTTCCAGTGTACCCATGAGCCCGCCATTCGGCTCGCGTCGAAAATCGCCTC
CCTTGCCCCCGGGCACATGAATCGGGTGTTCTTTACCGGTTCGGGTTCTGAGGCTAATGACACCAATCTGCGCATGGTAC
GACGTTACTGGGACTTGAAGGGGATGCCCTCCAAGAAAACCATTATCAGTCGCAAGAATGCCTACCACGGTTCAACCGTG
GCAGGTGCCAGCCTCGGCGGCATGGGGTTTATGCATCAGCAGGGCGATCTGCCAATTCCGGGGATTGTCCACATCGATCA
GCCCTACTGGTTCGGTGAAGGCCGCGATATGTCTCCTGAGGCCTTTGGCATTAAAACAGCACAGGCATTGGAAGCCAAAA
TCCTCGAACTCGGTGAAGATAAGGTTGCCGCTTTTATCGCCGAACCATTTCAGGGTGCAGGGGGAGTCATCATCCCACCA
GACAGCTACTGGAATGAAATTAAAAGGATTCTGGAAAAGTACAATATTCTGTTTATTCTGGATGAGGTCATCAGCGGCTT
TGGGCGTACCGGCAATTGGTTTGCCGCCCAGACTCTGGGGCTCAAACCCGATTTAATCACCATCGCCAAGGGGATGACCT
CGGGATACATCCCCATGGGCGGGGTGATAGTGTCCGACCGGGTTGCCGACGTGCTCATCAGTGATGGCGGCGAGTTTGCC
CATGGTTTTACCTACTCAGGCCATCCGGTTGCGGCGGCGGTAGCGCTGGAGAATATCCGTATTCTCGAAGAGGAGCGCCT
GGTGGATAAGGTCAGAACCGACACAGGACCTTATTTGCAGGATAGGTTGCAAACCCTGAGCGCGCATCCGCTGGTGGGAG
AGGTCAGGGGCATGGGCATGGTCGGTGCCATTGAATTGGTGGCAGACAAACACAGCATGGTGCGATTCGGCTCAGAAATA
TCGGCCGGTATGCTCTGCCGTGAGGCCTGTATCGAAAGCGGTTTGGTGATGCGTGCCGTGGGTGACACCATGATTATTTC
GCCGCCACTTTGCATTACTCGTGATGAGATTGACGAACTGATTTTTAAAGCAAGTCAGGCACTTTCGCTGACGCTTGAGA
AGATTGCAGCTCGGGGTAACTGA

Upstream 100 bases:

>100_bases
TTCAGGCGTGTTGTCAGTGCCTGGGAGCGTGAATTCCTGCTGCTGACAGTATAAAAACACAGGCCGGGGGTGACCCCGGC
ACTTTAGAGGGAGGGCGAAG

Downstream 100 bases:

>100_bases
GTGCATATTAAAAAGCCTGCCAATAGAGGAAGAGGTACTGGGCAGCAGCAACTGCCGATGCGGTTTTTCAGGTTGTAGCA
TTGGTCCTAACAATAAAATA

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MQQQQQDTISALQAMDAAHHLHPFTDSADLAKRGTRVIERAEGVYIWDAKGNKLLDAMAGLWCVNVGYGRKSIADAAYAQ
LQTLPFYNNFFQCTHEPAIRLASKIASLAPGHMNRVFFTGSGSEANDTNLRMVRRYWDLKGMPSKKTIISRKNAYHGSTV
AGASLGGMGFMHQQGDLPIPGIVHIDQPYWFGEGRDMSPEAFGIKTAQALEAKILELGEDKVAAFIAEPFQGAGGVIIPP
DSYWNEIKRILEKYNILFILDEVISGFGRTGNWFAAQTLGLKPDLITIAKGMTSGYIPMGGVIVSDRVADVLISDGGEFA
HGFTYSGHPVAAAVALENIRILEEERLVDKVRTDTGPYLQDRLQTLSAHPLVGEVRGMGMVGAIELVADKHSMVRFGSEI
SAGMLCREACIESGLVMRAVGDTMIISPPLCITRDEIDELIFKASQALSLTLEKIAARGN

Sequences:

>Translated_460_residues
MQQQQQDTISALQAMDAAHHLHPFTDSADLAKRGTRVIERAEGVYIWDAKGNKLLDAMAGLWCVNVGYGRKSIADAAYAQ
LQTLPFYNNFFQCTHEPAIRLASKIASLAPGHMNRVFFTGSGSEANDTNLRMVRRYWDLKGMPSKKTIISRKNAYHGSTV
AGASLGGMGFMHQQGDLPIPGIVHIDQPYWFGEGRDMSPEAFGIKTAQALEAKILELGEDKVAAFIAEPFQGAGGVIIPP
DSYWNEIKRILEKYNILFILDEVISGFGRTGNWFAAQTLGLKPDLITIAKGMTSGYIPMGGVIVSDRVADVLISDGGEFA
HGFTYSGHPVAAAVALENIRILEEERLVDKVRTDTGPYLQDRLQTLSAHPLVGEVRGMGMVGAIELVADKHSMVRFGSEI
SAGMLCREACIESGLVMRAVGDTMIISPPLCITRDEIDELIFKASQALSLTLEKIAARGN
>Mature_460_residues
MQQQQQDTISALQAMDAAHHLHPFTDSADLAKRGTRVIERAEGVYIWDAKGNKLLDAMAGLWCVNVGYGRKSIADAAYAQ
LQTLPFYNNFFQCTHEPAIRLASKIASLAPGHMNRVFFTGSGSEANDTNLRMVRRYWDLKGMPSKKTIISRKNAYHGSTV
AGASLGGMGFMHQQGDLPIPGIVHIDQPYWFGEGRDMSPEAFGIKTAQALEAKILELGEDKVAAFIAEPFQGAGGVIIPP
DSYWNEIKRILEKYNILFILDEVISGFGRTGNWFAAQTLGLKPDLITIAKGMTSGYIPMGGVIVSDRVADVLISDGGEFA
HGFTYSGHPVAAAVALENIRILEEERLVDKVRTDTGPYLQDRLQTLSAHPLVGEVRGMGMVGAIELVADKHSMVRFGSEI
SAGMLCREACIESGLVMRAVGDTMIISPPLCITRDEIDELIFKASQALSLTLEKIAARGN

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=456, Percent_Identity=28.0701754385965, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI226442705, Length=456, Percent_Identity=28.2894736842105, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI24119277, Length=427, Percent_Identity=28.1030444964871, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4557809, Length=444, Percent_Identity=27.2522522522523, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI226442709, Length=428, Percent_Identity=27.803738317757, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=28.5714285714286, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI284507298, Length=324, Percent_Identity=28.3950617283951, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI188536080, Length=482, Percent_Identity=22.4066390041494, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI38679950, Length=482, Percent_Identity=22.4066390041494, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI38679946, Length=482, Percent_Identity=22.4066390041494, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI145693181, Length=408, Percent_Identity=30.6372549019608, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1788044, Length=402, Percent_Identity=29.1044776119403, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=27.6190476190476, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1789016, Length=421, Percent_Identity=29.4536817102138, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786991, Length=443, Percent_Identity=27.5395033860045, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1787560, Length=357, Percent_Identity=31.0924369747899, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=412, Percent_Identity=28.3980582524272, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=439, Percent_Identity=28.9293849658314, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=29.7235023041475, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=244, Percent_Identity=33.6065573770492, Blast_Score=131, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323470, Length=451, Percent_Identity=26.8292682926829, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6324386, Length=469, Percent_Identity=26.4392324093817, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324432, Length=431, Percent_Identity=25.0580046403712, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=361, Percent_Identity=23.5457063711911, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356575, Length=429, Percent_Identity=30.5361305361305, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI161085790, Length=447, Percent_Identity=28.6353467561521, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=30.0469483568075, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21357415, Length=448, Percent_Identity=26.5625, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281366494, Length=391, Percent_Identity=22.2506393861893, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667139, Length=391, Percent_Identity=22.2506393861893, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667143, Length=391, Percent_Identity=22.2506393861893, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50103; Mature: 50103

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQQQDTISALQAMDAAHHLHPFTDSADLAKRGTRVIERAEGVYIWDAKGNKLLDAMAG
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHC
LWCVNVGYGRKSIADAAYAQLQTLPFYNNFFQCTHEPAIRLASKIASLAPGHMNRVFFTG
CEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEC
SGSEANDTNLRMVRRYWDLKGMPSKKTIISRKNAYHGSTVAGASLGGMGFMHQQGDLPIP
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
GIVHIDQPYWFGEGRDMSPEAFGIKTAQALEAKILELGEDKVAAFIAEPFQGAGGVIIPP
CEEEECCCEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECC
DSYWNEIKRILEKYNILFILDEVISGFGRTGNWFAAQTLGLKPDLITIAKGMTSGYIPMG
HHHHHHHHHHHHHCCEEEEHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCC
GVIVSDRVADVLISDGGEFAHGFTYSGHPVAAAVALENIRILEEERLVDKVRTDTGPYLQ
CEEECCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DRLQTLSAHPLVGEVRGMGMVGAIELVADKHSMVRFGSEISAGMLCREACIESGLVMRAV
HHHHHHHCCCCHHHHCCCCCHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEC
GDTMIISPPLCITRDEIDELIFKASQALSLTLEKIAARGN
CCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQQQQDTISALQAMDAAHHLHPFTDSADLAKRGTRVIERAEGVYIWDAKGNKLLDAMAG
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHC
LWCVNVGYGRKSIADAAYAQLQTLPFYNNFFQCTHEPAIRLASKIASLAPGHMNRVFFTG
CEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEC
SGSEANDTNLRMVRRYWDLKGMPSKKTIISRKNAYHGSTVAGASLGGMGFMHQQGDLPIP
CCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
GIVHIDQPYWFGEGRDMSPEAFGIKTAQALEAKILELGEDKVAAFIAEPFQGAGGVIIPP
CEEEECCCEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECC
DSYWNEIKRILEKYNILFILDEVISGFGRTGNWFAAQTLGLKPDLITIAKGMTSGYIPMG
HHHHHHHHHHHHHCCEEEEHHHHHHHCCCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCC
GVIVSDRVADVLISDGGEFAHGFTYSGHPVAAAVALENIRILEEERLVDKVRTDTGPYLQ
CEEECCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DRLQTLSAHPLVGEVRGMGMVGAIELVADKHSMVRFGSEISAGMLCREACIESGLVMRAV
HHHHHHHCCCCHHHHCCCCCHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEC
GDTMIISPPLCITRDEIDELIFKASQALSLTLEKIAARGN
CCEEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]