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The map label for this gene is dipZ [H]

Identifier: 119773678

GI number: 119773678

Start: 663245

End: 665068

Strand: Reverse

Name: dipZ [H]

Synonym: Sama_0538

Alternate gene names: 119773678

Gene position: 665068-663245 (Counterclockwise)

Preceding gene: 119773679

Following gene: 119773677

Centisome position: 15.44

GC content: 54.28

Gene sequence:

>1824_bases
ATGAAAAAAATCATCACCCTGCTGTTTAGTTGTCTGCTGTTATTGGCCCCATCGACCCATGCCAATGATATTTTTGGTAA
AAAATTCGATTTCCTCAAGGGCGAGCCCGAGCTGATGCCCGTGAATGAAGCCTTTGTGTTTGATGCCGTCCAGGACGGGA
ATCGGGTGCGGGTGTCCTTTGTGATTGCCGATGGCTATTACCTTTACCGCGACAAACTCAAGTTTGAAGCCGACAACGCC
ACCCTGGGTGAGGTCGCGCTGCCGCCGGGTAAGCTGCACAACGACGAGTACTTTGGCGAGCAGCAGGTATTTTACAGCTA
TGTTGAGTTTACCGTTGCCCTCAAAGAAGCCATGGATCAGGGTACACTGACCCTCACCTTCATGGGCTGCGCCGAAGGCA
AACTCTGCTTCCCACCCACCAGGGTCAGCAAGCAGCTTACCGCTGTGGCCCCCAACGATGGCAAGCTGTCAGGCGAATCC
GCAAAACCTGTATCTGACGGCACAGTATCAGGCACTTCAACCTCTGCACCTCTGACCCAACAGGACAGTCTGGCGCAGAT
GCTGACCGAAGGAAACCTCGGTTGGACCTTGCTGATTTTCTTCGGTTTGGGCATTGGTTTAGCGCTTACGCCCTGCGTAT
TCCCCATGTACCCTATTCTGTCGGGCATTATCGTCGGTCAGGGTGAAAAGTTATCCACGGGCCGCGCCTTTACCCTGTCC
ATGGCCTATGTGCAAGGTATGGCGATTACCTATTCGCTGCTGGGTTTGGTGGTGGCGTCGGCAGGGATGAAATATCAAGC
CGCGCTGCAACACCCAGCGGTACTGATTGGTCTGGCGATACTCTTCTTCGTCCTCAGCCTGTCTATGTTTGGCCTGTATG
ACCTCAAATTGCCCTCTTCCTGGCAGGAAAAGATGAATGGCCTGTCCAACAACCAGAAAGGTGGCAACCTCACCGGCGTC
TTCATTATGGGGGTGATCTCCGGTCTGGTGGCATCGCCATGCACCACGGCCCCCTTGTCGGGCGCTCTGGTGTACGTGGC
GCAAAGTGGCGACCTGCTGATGGGCTTTGCCGCCCTGTACGTGCTTAGTATGGGCATGGGTCTGCCATTGCTGCTGATGG
GCACTTCCGGTGGTAAATTGCTGCCCCGCGCAGGCGCCTGGATGGAAATCATCAAGACTGTGTTTGGCTTCCTGTTAATT
GCGGTATCTGTGATGATGATTGGTCGTATCTGGCCAGGTATGGTGTCCGATTTGCTGTGGGCTCTGTGGGGCGTAGCACT
TGCGGGCTATCTGCTGCATCAAAACAAAAAGACCGAATTCAACTGGAAACAAACCGTGCGCACTGTGCTGCTGATGCTCG
GACTGCTGGCCGCATTCTCTTACGGCTTCCAGGCTGTGATGGGCGGTTTGGGCTATCAGATGCCCACCAACAATACTGCA
CAACAATCCGTAAAAGGGGTTGAATTCAAGCGCATCAAGTCAGTAGAAGATCTCAATGCCGAGCTGGCCATAGCCCGCTT
TGAAGGCAAGTTTGTGATGCTGGACCTCTACGCCGACTGGTGTGTGGCCTGTAAGGAATTTGAGCACATTACGTTCCCTG
ATCCGGAAGTGAAAAAGCGCCTGGATAACATGGTGCTGCTTCAGGCCGATGTGACCAAGTCTGACGCCATCGACGTAACC
TTGCTGGAGACCTACGATGTGCTTGGTCTGCCGACACTGCTGCTGTTCGATCCCCAGAGCGGCCTGCGTGATGACTTAAG
AGTCACCGGCTTTATGGGCCCCAAAGACTTTGCGGCGCACCTGGACCTGCTGCAAGTGCATTAA

Upstream 100 bases:

>100_bases
TTTCTGAGCTGCATCCCTATGAGTTGCCTGAGATTATCGCGACGCCCGTAACCGAGGCCCTGCCCGGCTATTTGAACTGG
ATAAACGACAATACACAATC

Downstream 100 bases:

>100_bases
TCCCCTTTTTCCCTTATAACTAAAGGCAAAGATTTCACTGAAATCTTTGCCTTTTTCATCTCACATTAAATAAAGTCCGC
TAAGATACCTGATTTATAGC

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MKKIITLLFSCLLLLAPSTHANDIFGKKFDFLKGEPELMPVNEAFVFDAVQDGNRVRVSFVIADGYYLYRDKLKFEADNA
TLGEVALPPGKLHNDEYFGEQQVFYSYVEFTVALKEAMDQGTLTLTFMGCAEGKLCFPPTRVSKQLTAVAPNDGKLSGES
AKPVSDGTVSGTSTSAPLTQQDSLAQMLTEGNLGWTLLIFFGLGIGLALTPCVFPMYPILSGIIVGQGEKLSTGRAFTLS
MAYVQGMAITYSLLGLVVASAGMKYQAALQHPAVLIGLAILFFVLSLSMFGLYDLKLPSSWQEKMNGLSNNQKGGNLTGV
FIMGVISGLVASPCTTAPLSGALVYVAQSGDLLMGFAALYVLSMGMGLPLLLMGTSGGKLLPRAGAWMEIIKTVFGFLLI
AVSVMMIGRIWPGMVSDLLWALWGVALAGYLLHQNKKTEFNWKQTVRTVLLMLGLLAAFSYGFQAVMGGLGYQMPTNNTA
QQSVKGVEFKRIKSVEDLNAELAIARFEGKFVMLDLYADWCVACKEFEHITFPDPEVKKRLDNMVLLQADVTKSDAIDVT
LLETYDVLGLPTLLLFDPQSGLRDDLRVTGFMGPKDFAAHLDLLQVH

Sequences:

>Translated_607_residues
MKKIITLLFSCLLLLAPSTHANDIFGKKFDFLKGEPELMPVNEAFVFDAVQDGNRVRVSFVIADGYYLYRDKLKFEADNA
TLGEVALPPGKLHNDEYFGEQQVFYSYVEFTVALKEAMDQGTLTLTFMGCAEGKLCFPPTRVSKQLTAVAPNDGKLSGES
AKPVSDGTVSGTSTSAPLTQQDSLAQMLTEGNLGWTLLIFFGLGIGLALTPCVFPMYPILSGIIVGQGEKLSTGRAFTLS
MAYVQGMAITYSLLGLVVASAGMKYQAALQHPAVLIGLAILFFVLSLSMFGLYDLKLPSSWQEKMNGLSNNQKGGNLTGV
FIMGVISGLVASPCTTAPLSGALVYVAQSGDLLMGFAALYVLSMGMGLPLLLMGTSGGKLLPRAGAWMEIIKTVFGFLLI
AVSVMMIGRIWPGMVSDLLWALWGVALAGYLLHQNKKTEFNWKQTVRTVLLMLGLLAAFSYGFQAVMGGLGYQMPTNNTA
QQSVKGVEFKRIKSVEDLNAELAIARFEGKFVMLDLYADWCVACKEFEHITFPDPEVKKRLDNMVLLQADVTKSDAIDVT
LLETYDVLGLPTLLLFDPQSGLRDDLRVTGFMGPKDFAAHLDLLQVH
>Mature_607_residues
MKKIITLLFSCLLLLAPSTHANDIFGKKFDFLKGEPELMPVNEAFVFDAVQDGNRVRVSFVIADGYYLYRDKLKFEADNA
TLGEVALPPGKLHNDEYFGEQQVFYSYVEFTVALKEAMDQGTLTLTFMGCAEGKLCFPPTRVSKQLTAVAPNDGKLSGES
AKPVSDGTVSGTSTSAPLTQQDSLAQMLTEGNLGWTLLIFFGLGIGLALTPCVFPMYPILSGIIVGQGEKLSTGRAFTLS
MAYVQGMAITYSLLGLVVASAGMKYQAALQHPAVLIGLAILFFVLSLSMFGLYDLKLPSSWQEKMNGLSNNQKGGNLTGV
FIMGVISGLVASPCTTAPLSGALVYVAQSGDLLMGFAALYVLSMGMGLPLLLMGTSGGKLLPRAGAWMEIIKTVFGFLLI
AVSVMMIGRIWPGMVSDLLWALWGVALAGYLLHQNKKTEFNWKQTVRTVLLMLGLLAAFSYGFQAVMGGLGYQMPTNNTA
QQSVKGVEFKRIKSVEDLNAELAIARFEGKFVMLDLYADWCVACKEFEHITFPDPEVKKRLDNMVLLQADVTKSDAIDVT
LLETYDVLGLPTLLLFDPQSGLRDDLRVTGFMGPKDFAAHLDLLQVH

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=594, Percent_Identity=43.4343434343434, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 65935; Mature: 65935

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIITLLFSCLLLLAPSTHANDIFGKKFDFLKGEPELMPVNEAFVFDAVQDGNRVRVSF
CHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCEEECCHHEEEEECCCCCEEEEEE
VIADGYYLYRDKLKFEADNATLGEVALPPGKLHNDEYFGEQQVFYSYVEFTVALKEAMDQ
EEECCEEEEECCEEEECCCCCCCCEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCC
GTLTLTFMGCAEGKLCFPPTRVSKQLTAVAPNDGKLSGESAKPVSDGTVSGTSTSAPLTQ
CCEEEEEEECCCCCEECCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QDSLAQMLTEGNLGWTLLIFFGLGIGLALTPCVFPMYPILSGIIVGQGEKLSTGRAFTLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCEEEEH
MAYVQGMAITYSLLGLVVASAGMKYQAALQHPAVLIGLAILFFVLSLSMFGLYDLKLPSS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCEEEECCCCH
WQEKMNGLSNNQKGGNLTGVFIMGVISGLVASPCTTAPLSGALVYVAQSGDLLMGFAALY
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
VLSMGMGLPLLLMGTSGGKLLPRAGAWMEIIKTVFGFLLIAVSVMMIGRIWPGMVSDLLW
HHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ALWGVALAGYLLHQNKKTEFNWKQTVRTVLLMLGLLAAFSYGFQAVMGGLGYQMPTNNTA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
QQSVKGVEFKRIKSVEDLNAELAIARFEGKFVMLDLYADWCVACKEFEHITFPDPEVKKR
HHHHCCCHHHHHHCHHHCCCEEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHH
LDNMVLLQADVTKSDAIDVTLLETYDVLGLPTLLLFDPQSGLRDDLRVTGFMGPKDFAAH
HCCEEEEEECCCCCCCEEEEEEEHHHHHCCCEEEEECCCCCCCCCCEEEECCCCHHHHHH
LDLLQVH
HHHHCCC
>Mature Secondary Structure
MKKIITLLFSCLLLLAPSTHANDIFGKKFDFLKGEPELMPVNEAFVFDAVQDGNRVRVSF
CHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCEEECCHHEEEEECCCCCEEEEEE
VIADGYYLYRDKLKFEADNATLGEVALPPGKLHNDEYFGEQQVFYSYVEFTVALKEAMDQ
EEECCEEEEECCEEEECCCCCCCCEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCC
GTLTLTFMGCAEGKLCFPPTRVSKQLTAVAPNDGKLSGESAKPVSDGTVSGTSTSAPLTQ
CCEEEEEEECCCCCEECCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QDSLAQMLTEGNLGWTLLIFFGLGIGLALTPCVFPMYPILSGIIVGQGEKLSTGRAFTLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCEEEEH
MAYVQGMAITYSLLGLVVASAGMKYQAALQHPAVLIGLAILFFVLSLSMFGLYDLKLPSS
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHCEEEECCCCH
WQEKMNGLSNNQKGGNLTGVFIMGVISGLVASPCTTAPLSGALVYVAQSGDLLMGFAALY
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
VLSMGMGLPLLLMGTSGGKLLPRAGAWMEIIKTVFGFLLIAVSVMMIGRIWPGMVSDLLW
HHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ALWGVALAGYLLHQNKKTEFNWKQTVRTVLLMLGLLAAFSYGFQAVMGGLGYQMPTNNTA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
QQSVKGVEFKRIKSVEDLNAELAIARFEGKFVMLDLYADWCVACKEFEHITFPDPEVKKR
HHHHCCCHHHHHHCHHHCCCEEEEEEECCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHH
LDNMVLLQADVTKSDAIDVTLLETYDVLGLPTLLLFDPQSGLRDDLRVTGFMGPKDFAAH
HCCEEEEEECCCCCCCEEEEEEEHHHHHCCCEEEEECCCCCCCCCCEEEECCCCHHHHHH
LDLLQVH
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA