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The map label for this gene is plsC [H]

Identifier: 119717328

GI number: 119717328

Start: 3307422

End: 3308165

Strand: Reverse

Name: plsC [H]

Synonym: Noca_3104

Alternate gene names: 119717328

Gene position: 3308165-3307422 (Counterclockwise)

Preceding gene: 119717332

Following gene: 119717327

Centisome position: 66.35

GC content: 70.03

Gene sequence:

>744_bases
GTGTTCTACTGGTTCTTGAAGTGGATCGCCCTCGGACCGTGGCTGCGCCTGGTGTTCCGGCCCCGCGTGTACGGCGCCGA
GAACGTCCCGCTCGAGGGCCCCGCGATCCTGGCCAGCAACCATCTGTCGTACGCCGACTGGCTGTTCATGCCGCTCACGC
TCCCGCGCCGCGTGACGTTCGTGGCCAAGGCCGAGTACTTCACCGGCAAGGGCCTCAAGGGCTGGCTGCAGCGGACGTTC
TTCGCGGGATCCGGCCAGGTGCCGATCGACCGGTCGGGAGGCGGCGCCGCAGAGGGCGCGATCATCTCCGCCAAGCGGGT
GCTCGCCGAGGGCGAGCTGTTCGGCATCTATCCGGAGGGCACCCGCTCGCACGACGGGCGGCTCTACCGCGGCAAGGTCG
GCGTCGCGCGGCTGGCGCTCGAGGCGAAGGTGCCGGTGGTCCCGGTCGCGGTCCTCGGCACCGACGTGGTGGCGCCGCCG
GGCAAGAAGTTCGGCCGGTTCACCCGCCCGGTCGTGCGCTTCGGGGCGCCGCTGGACTTCTCCCGCTACGACGGGATGGA
GAGCGACCGCTACATCCTGCGCTCGATCACCGACGAGATCATGTACGAGATCATGCGCCTCTCCGGCCAGGAGTACGTCG
ACATGTACGGCGCCCGGGCGAAGGAGGAGTCGCGGAAGAGCGAGAAGGACGCGGCCGCGCAGCAGGAGCCGGGTGAGCCC
GACGAGCCCAAGCTCGCGTCTTGA

Upstream 100 bases:

>100_bases
GCCGCACCCGAGGGTCCGGCCGACCTCGGTATGGGGGAAGTCGCGCGCGACGGTCTAGGCTTCGCCCGTCGGATGTCTCG
GGTCGGTTGGGAGGTCGTCG

Downstream 100 bases:

>100_bases
CGATCCACTCCGCGCACCCGTTCCTCGACCCGGAGCCCGACCCGGTCCGCCGGTTCCGCGGCCGGATCACCGGCACCGTC
GCCTTGGTGACCGCCGGTGA

Product: phospholipid/glycerol acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MFYWFLKWIALGPWLRLVFRPRVYGAENVPLEGPAILASNHLSYADWLFMPLTLPRRVTFVAKAEYFTGKGLKGWLQRTF
FAGSGQVPIDRSGGGAAEGAIISAKRVLAEGELFGIYPEGTRSHDGRLYRGKVGVARLALEAKVPVVPVAVLGTDVVAPP
GKKFGRFTRPVVRFGAPLDFSRYDGMESDRYILRSITDEIMYEIMRLSGQEYVDMYGARAKEESRKSEKDAAAQQEPGEP
DEPKLAS

Sequences:

>Translated_247_residues
MFYWFLKWIALGPWLRLVFRPRVYGAENVPLEGPAILASNHLSYADWLFMPLTLPRRVTFVAKAEYFTGKGLKGWLQRTF
FAGSGQVPIDRSGGGAAEGAIISAKRVLAEGELFGIYPEGTRSHDGRLYRGKVGVARLALEAKVPVVPVAVLGTDVVAPP
GKKFGRFTRPVVRFGAPLDFSRYDGMESDRYILRSITDEIMYEIMRLSGQEYVDMYGARAKEESRKSEKDAAAQQEPGEP
DEPKLAS
>Mature_247_residues
MFYWFLKWIALGPWLRLVFRPRVYGAENVPLEGPAILASNHLSYADWLFMPLTLPRRVTFVAKAEYFTGKGLKGWLQRTF
FAGSGQVPIDRSGGGAAEGAIISAKRVLAEGELFGIYPEGTRSHDGRLYRGKVGVARLALEAKVPVVPVAVLGTDVVAPP
GKKFGRFTRPVVRFGAPLDFSRYDGMESDRYILRSITDEIMYEIMRLSGQEYVDMYGARAKEESRKSEKDAAAQQEPGEP
DEPKLAS

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=136, Percent_Identity=34.5588235294118, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15100175, Length=136, Percent_Identity=34.5588235294118, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 27481; Mature: 27481

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYWFLKWIALGPWLRLVFRPRVYGAENVPLEGPAILASNHLSYADWLFMPLTLPRRVTF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHEEECCCCCCEEEE
VAKAEYFTGKGLKGWLQRTFFAGSGQVPIDRSGGGAAEGAIISAKRVLAEGELFGIYPEG
EEECCHHCCCCHHHHHHHHEECCCCCCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCC
TRSHDGRLYRGKVGVARLALEAKVPVVPVAVLGTDVVAPPGKKFGRFTRPVVRFGAPLDF
CCCCCCEEEECCCCEEHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCH
SRYDGMESDRYILRSITDEIMYEIMRLSGQEYVDMYGARAKEESRKSEKDAAAQQEPGEP
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
DEPKLAS
CCCCCCC
>Mature Secondary Structure
MFYWFLKWIALGPWLRLVFRPRVYGAENVPLEGPAILASNHLSYADWLFMPLTLPRRVTF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCHHHHEEECCCCCCEEEE
VAKAEYFTGKGLKGWLQRTFFAGSGQVPIDRSGGGAAEGAIISAKRVLAEGELFGIYPEG
EEECCHHCCCCHHHHHHHHEECCCCCCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCC
TRSHDGRLYRGKVGVARLALEAKVPVVPVAVLGTDVVAPPGKKFGRFTRPVVRFGAPLDF
CCCCCCEEEECCCCEEHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCH
SRYDGMESDRYILRSITDEIMYEIMRLSGQEYVDMYGARAKEESRKSEKDAAAQQEPGEP
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
DEPKLAS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]