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The map label for this gene is galE [C]

Identifier: 119717217

GI number: 119717217

Start: 3183339

End: 3184379

Strand: Reverse

Name: galE [C]

Synonym: Noca_2993

Alternate gene names: 119717217

Gene position: 3184379-3183339 (Counterclockwise)

Preceding gene: 119717218

Following gene: 119717215

Centisome position: 63.87

GC content: 68.68

Gene sequence:

>1041_bases
GTGACCGAGGGAGCGGGCCAGCGGGTCCTGGTGACCGGGTCGGCCGGGTTCATCGGCGGCTATGTCGTGGAGGACCTCCT
CCGTCGTGGGTACGCCGTGACCGGGATCGACAACTACTCCAAGTACGGTCCGGTCACGAAGTCCTACGACGACCATCCGG
CGTACCACTTCGTCGAGGGCGACGTGCGCGACCTCGAGCTGATGGCCGACCTCGTCGCCGACTGCGACCACCTCGTCGCG
GGGGCGGCCCTGATCGGCGGGATCTCCTACTTCCACACCTACCCCTACGACCTGCTCGCGACCAACGAGCGGATCATCGC
GGCCACCTGTGACACCGCGATCCGGGCGATGCCCGCCGGCCGGCTGCGCAAGGTGACCTATCTCAGCTCCTCGATGGTCT
TCGAGTCCACGGACCGATGGCCGTCGAAGGAAGGCGACGAGCGGGTGATCCCGCCGCCGCTGTCGTCGTACGGCTTCCAG
AAGCTCGCGGTGGAGTACTTCGCCCGCGCGGCCTGGGACCAGTACCGCGTCCCCTACACCATCGTCCGCCCGTTCAACTG
CGTCGGGGTGGGGGAGGGCCGCGCGCTCGGCGACGTCGAGATCCCGAGCGGCAACATCAAGCTCGCGATGAGCCACGTGG
TCCCGGACCTGATCCAGAAGGTGCTCCGGGGCCAGGATCCGGTGCACGTGCTCGGCGACGGCAGCCAGGTGCGGCACTAC
ACCTACGGTGCGGACCTCGCCGAAGGCATCATCCGCGCGATGTCGTCCGAGCGGGCGCTCAACGACGACTTCAACCTCTC
CACCGCCCGGTCGACCACCGTGCTCGAGCTGGCCGAGCTGATCTGGCGAAAGTGCCATGGGCCGGACCGCCCGTTCGCGG
TCGTGAGCGACGAGCCGTTCGAGCACGACGTGCAGCGTCGCGTCCCCGACGTCACCAAGGCCGAGGAGGTCCTCGGCTTC
CGGGCCACCACCACGCTGGACGAGATGCTCGACGTGGTGATCCCGTGGGTGGCGCAGGCCCTCCAGGACGGCCTGATCTG
A

Upstream 100 bases:

>100_bases
TGCGCTGGTACCGCTTCGCCTTCGGTCCAGAGCTCACCGTCGAGCAGGTGCGCGCCGAGGGTGCGAGGATCGCTGCTCGC
AACGACAGGAGGGGACGTCC

Downstream 100 bases:

>100_bases
CGAGGGTCCGACCGGGCTGCCGGGTCAGGGCCGCCGGCCGACGACCAACATCTGCTTGCCGAGGACCCGCCAGGCCGGGC
GGCAGCGCAGGTAGCCGCGT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTEGAGQRVLVTGSAGFIGGYVVEDLLRRGYAVTGIDNYSKYGPVTKSYDDHPAYHFVEGDVRDLELMADLVADCDHLVA
GAALIGGISYFHTYPYDLLATNERIIAATCDTAIRAMPAGRLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQ
KLAVEYFARAAWDQYRVPYTIVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKVLRGQDPVHVLGDGSQVRHY
TYGADLAEGIIRAMSSERALNDDFNLSTARSTTVLELAELIWRKCHGPDRPFAVVSDEPFEHDVQRRVPDVTKAEEVLGF
RATTTLDEMLDVVIPWVAQALQDGLI

Sequences:

>Translated_346_residues
MTEGAGQRVLVTGSAGFIGGYVVEDLLRRGYAVTGIDNYSKYGPVTKSYDDHPAYHFVEGDVRDLELMADLVADCDHLVA
GAALIGGISYFHTYPYDLLATNERIIAATCDTAIRAMPAGRLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQ
KLAVEYFARAAWDQYRVPYTIVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKVLRGQDPVHVLGDGSQVRHY
TYGADLAEGIIRAMSSERALNDDFNLSTARSTTVLELAELIWRKCHGPDRPFAVVSDEPFEHDVQRRVPDVTKAEEVLGF
RATTTLDEMLDVVIPWVAQALQDGLI
>Mature_345_residues
TEGAGQRVLVTGSAGFIGGYVVEDLLRRGYAVTGIDNYSKYGPVTKSYDDHPAYHFVEGDVRDLELMADLVADCDHLVAG
AALIGGISYFHTYPYDLLATNERIIAATCDTAIRAMPAGRLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQK
LAVEYFARAAWDQYRVPYTIVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKVLRGQDPVHVLGDGSQVRHYT
YGADLAEGIIRAMSSERALNDDFNLSTARSTTVLELAELIWRKCHGPDRPFAVVSDEPFEHDVQRRVPDVTKAEEVLGFR
ATTTLDEMLDVVIPWVAQALQDGLI

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=349, Percent_Identity=25.7879656160458, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786974, Length=359, Percent_Identity=28.133704735376, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788365, Length=348, Percent_Identity=23.5632183908046, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=25.8928571428571, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21356223, Length=342, Percent_Identity=25.7309941520468, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38144; Mature: 38012

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGAGQRVLVTGSAGFIGGYVVEDLLRRGYAVTGIDNYSKYGPVTKSYDDHPAYHFVEG
CCCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHCCCCCCCCCCCCCEEEECC
DVRDLELMADLVADCDHLVAGAALIGGISYFHTYPYDLLATNERIIAATCDTAIRAMPAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEHHHHHHHCCCC
RLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQKLAVEYFARAAWDQYRVPYT
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
IVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKVLRGQDPVHVLGDGSQVRHY
EECCCEEEECCCCCCCCCEECCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCEEEEE
TYGADLAEGIIRAMSSERALNDDFNLSTARSTTVLELAELIWRKCHGPDRPFAVVSDEPF
ECCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCH
EHDVQRRVPDVTKAEEVLGFRATTTLDEMLDVVIPWVAQALQDGLI
HHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEGAGQRVLVTGSAGFIGGYVVEDLLRRGYAVTGIDNYSKYGPVTKSYDDHPAYHFVEG
CCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHCCCCCCCCCCCCCEEEECC
DVRDLELMADLVADCDHLVAGAALIGGISYFHTYPYDLLATNERIIAATCDTAIRAMPAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEEHHHHHHHCCCC
RLRKVTYLSSSMVFESTDRWPSKEGDERVIPPPLSSYGFQKLAVEYFARAAWDQYRVPYT
HHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
IVRPFNCVGVGEGRALGDVEIPSGNIKLAMSHVVPDLIQKVLRGQDPVHVLGDGSQVRHY
EECCCEEEECCCCCCCCCEECCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECCCCEEEEE
TYGADLAEGIIRAMSSERALNDDFNLSTARSTTVLELAELIWRKCHGPDRPFAVVSDEPF
ECCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCH
EHDVQRRVPDVTKAEEVLGFRATTTLDEMLDVVIPWVAQALQDGLI
HHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]