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The map label for this gene is cobM [H]

Identifier: 119717115

GI number: 119717115

Start: 3075011

End: 3075796

Strand: Reverse

Name: cobM [H]

Synonym: Noca_2891

Alternate gene names: 119717115

Gene position: 3075796-3075011 (Counterclockwise)

Preceding gene: 119717116

Following gene: 119717113

Centisome position: 61.69

GC content: 72.9

Gene sequence:

>786_bases
ATGACGAAGCCTGCCACGATCGTCCACTTCGTCGGGGCCGGACCCGGCGCCGCCGATCTGTTGACGGTGCGCGCGACCAG
GCTGCTGGGCGAGGCGGACGTGGTGCTCTATCCGGGCACCTACCTCGACCCCGACGTCCTCTCCCACGTGAGCCCCGGCG
CCGAGCTGGTGGACACCCAGGGTCTCGACCTCGACCAGATCAGCGCGTGCCTGATCGCCGCCGCCCGGACGGCCAAGCAG
GTGGTGCGCCTGACCTCCGGGGACCCCTCGCTCTACTCCGCCCTGGCTGAGCAGACCCGGCGGCTCGCCGCTGAGGGAGT
CGCGTGGGATGTGACGCCCGGGGTGCCGGCGTACGCGGCGGCGGCGGCGCTCGTCGGCACCGAGCTCACGGTGCCGTTGG
TGAGCCAGTCCGTCGTGCTGACCCGCACCCGGGCACGCTCGAGCGCGATGCCCGAGACCGAGGCACTCGCGACCTTCGCC
AGCACCCGCGCGACCTTGGTCCTCCACCTCGCGATCACCCGGGTGCGGGCGATCATGGCCGAGATCGAGCCGGAGCACGG
CGCCGACTGTCCCGTCGTGGTGGTCCACCGGGCCAGTCAGCCCGGCGAGCGCGTGCTGCGCGGGACGGTCGCGACGATCG
CCGACCTCGTCGACGACGCAGACCTCCGGCAGGCAGCCGTGATCCTGGTCGGCCGGGCACTGGCCGATGACGGCGGCGAG
TCCTGGCTCTACGCCGCTCACCGCGACAGGAGCGTCACGAGCCCTTCGCGTACGCCCACTGGGTGA

Upstream 100 bases:

>100_bases
CGGCCACGATCGACATGAAGTGCCTGCTGATCGTTGGCGCCACCTCGACCCGCGTCACGCGCGGCCGGGTCTGGACACCG
CGGTTCGTGAAGGCCGGCCC

Downstream 100 bases:

>100_bases
CGGCACGTGCGGGCGTCCAACCGGTGAAGGTCCCGACCGGGCCGGCCGACTCGACGGAGATCCGGGTCAGCTCGCCACCC
TGCTCCTCGTAGAGCCGAGC

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTKPATIVHFVGAGPGAADLLTVRATRLLGEADVVLYPGTYLDPDVLSHVSPGAELVDTQGLDLDQISACLIAAARTAKQ
VVRLTSGDPSLYSALAEQTRRLAAEGVAWDVTPGVPAYAAAAALVGTELTVPLVSQSVVLTRTRARSSAMPETEALATFA
STRATLVLHLAITRVRAIMAEIEPEHGADCPVVVVHRASQPGERVLRGTVATIADLVDDADLRQAAVILVGRALADDGGE
SWLYAAHRDRSVTSPSRTPTG

Sequences:

>Translated_261_residues
MTKPATIVHFVGAGPGAADLLTVRATRLLGEADVVLYPGTYLDPDVLSHVSPGAELVDTQGLDLDQISACLIAAARTAKQ
VVRLTSGDPSLYSALAEQTRRLAAEGVAWDVTPGVPAYAAAAALVGTELTVPLVSQSVVLTRTRARSSAMPETEALATFA
STRATLVLHLAITRVRAIMAEIEPEHGADCPVVVVHRASQPGERVLRGTVATIADLVDDADLRQAAVILVGRALADDGGE
SWLYAAHRDRSVTSPSRTPTG
>Mature_260_residues
TKPATIVHFVGAGPGAADLLTVRATRLLGEADVVLYPGTYLDPDVLSHVSPGAELVDTQGLDLDQISACLIAAARTAKQV
VRLTSGDPSLYSALAEQTRRLAAEGVAWDVTPGVPAYAAAAALVGTELTVPLVSQSVVLTRTRARSSAMPETEALATFAS
TRATLVLHLAITRVRAIMAEIEPEHGADCPVVVVHRASQPGERVLRGTVATIADLVDDADLRQAAVILVGRALADDGGES
WLYAAHRDRSVTSPSRTPTG

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=248, Percent_Identity=28.2258064516129, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322922, Length=236, Percent_Identity=25, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 27227; Mature: 27096

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPATIVHFVGAGPGAADLLTVRATRLLGEADVVLYPGTYLDPDVLSHVSPGAELVDTQ
CCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCHHHCCC
GLDLDQISACLIAAARTAKQVVRLTSGDPSLYSALAEQTRRLAAEGVAWDVTPGVPAYAA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHH
AAALVGTELTVPLVSQSVVLTRTRARSSAMPETEALATFASTRATLVLHLAITRVRAIMA
HHHHHCCCCCHHHHCCHHHEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEPEHGADCPVVVVHRASQPGERVLRGTVATIADLVDDADLRQAAVILVGRALADDGGE
HCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
SWLYAAHRDRSVTSPSRTPTG
CEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKPATIVHFVGAGPGAADLLTVRATRLLGEADVVLYPGTYLDPDVLSHVSPGAELVDTQ
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCHHHCCC
GLDLDQISACLIAAARTAKQVVRLTSGDPSLYSALAEQTRRLAAEGVAWDVTPGVPAYAA
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHH
AAALVGTELTVPLVSQSVVLTRTRARSSAMPETEALATFASTRATLVLHLAITRVRAIMA
HHHHHCCCCCHHHHCCHHHEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEPEHGADCPVVVVHRASQPGERVLRGTVATIADLVDDADLRQAAVILVGRALADDGGE
HCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCC
SWLYAAHRDRSVTSPSRTPTG
CEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]