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The map label for this gene is cobIJ [H]

Identifier: 119717116

GI number: 119717116

Start: 3075793

End: 3077316

Strand: Reverse

Name: cobIJ [H]

Synonym: Noca_2892

Alternate gene names: 119717116

Gene position: 3077316-3075793 (Counterclockwise)

Preceding gene: 119717117

Following gene: 119717115

Centisome position: 61.72

GC content: 71.46

Gene sequence:

>1524_bases
ATGAACGGCACGTTCACGGTCGTGGGAATCGGCCCGGGCGATCCGGAGCTGATGACCCTCAAGGCCGTTCGCCTCATCGG
CGACGCGCAGGTCGTCGCCTTCCATGCGGGCGTGAAGAAGCGGTCGCACGCCCGCCGCATCGCCGATTCCGTGATCCCGG
CGGGAGCGATCGAGGAGGAGTTGCGCTATCCGGTGACGACCGGAACGACCGACCACCCGGGCGGGTACGTCGGCGCGATG
GCCGACTTCTACGAGGAGTGCGCCGTACGACTGTCCGCGCACCTGGACGCCGGGCGGGACGTCGTGCTCCTCGCTGAGGG
GGACCCGCTGTTCTACGGCTCGTCGATGTACCTGCACGACCGGTTCAAGCACGCCTATGACACGGCGGTGGTGCCGGGCG
TGCCTGCGTTCGCCGCGGCGACGGCTGCGGTCTCGACGCCGTTGGTCAGGCAGACCGACGTCCTCACGGTGCTGACGGGC
ACGCTGCCTGAGCCCGAGCTGGCCCGCAGGCTGGCCGACACCGACGGCGCGATCATCATGAAGCTCGGTCGTACCTTCCC
CGCCGTGCGGTCCGCACTGGAGCAGGCCGGACGGCTCGACGGTGCGTGGTACGTCGAGCGTGCCTCGCAGGCGGAAGAGC
GTTGGCTGCCCGTGGCCGAGGTGGACCCGGACTCGGTGCCCTACTTCTCGCTCGTCTTCGTGCCGGGTGACACGGCCCAG
ACGCCGAGTGCGGAGCGCATGCGGGTGGGCCTCCTCGATGGCGGACCCGTGGTGGCGGAGAGGCCGGCGGCCGAGCTGCT
GGTCGTGGGCCTGGGCCCGGGACCGGACGGCTGGCTGACTCCGGAGGCCGCCGATGCGCTTGCCGGCGTCGACCATGTCG
TCGGCTACGGCCGCTACGTCGAGCGGGTACCGCAACGCGCGGGCCTGACGCGCCACGCCAGCGGCAACACGGTCGAGGTC
GATCGCGCCCGTGCAGCGCTCGACCTGGCCCGGGCAGGGGAGAAGGTGGCCGTGGTGTCCGGCGGCGACGCCGGCGTGTT
CGGGATGGCATCGGCTGTCTTCGAGGCCGCCGAGGATCCGGCGTACGCCGACGTCACGATCCGGGTCCTGCCCGGACTGA
GCGCGGTCCAGGCGGTCGCGGCACGTGCTGGCGCGCCGATCGGTGCCGACTTCGCCGTCGTCTCCCTCAGCGACCGGCTC
AAGCCGTGGGAGGTCGTCGAGCGACGCCTGCGAGCCATCGCGGAGGCCGACCTCGTGCTCGCGATCTACAACCCGTCTTC
GCGCTCACGGACCGGACAGCTCGCCACGGCTCGCGACGTGCTCCTGGAGCACCGGAAGCCGGACACGGTGGTCATCGTCG
GTCGCGACATCGGCCGGGCCGAGGAGTCGCTCGTCGTCACCACGCTCGGCGACCTCGACCCGGCCACGATCGACATGAAG
TGCCTGCTGATCGTTGGCGCCACCTCGACCCGCGTCACGCGCGGCCGGGTCTGGACACCGCGGTTCGTGAAGGCCGGCCC
ATGA

Upstream 100 bases:

>100_bases
ACCAGCATGGGATCGACATCCCCTTCGTCACCGTCCGCGGTCGCCGTGGCGGTTCGGCGATGACCTCCTCCGCACTCAAC
GCACTCGCCCAGGAGATCGA

Downstream 100 bases:

>100_bases
CGAAGCCTGCCACGATCGTCCACTTCGTCGGGGCCGGACCCGGCGCCGCCGATCTGTTGACGGTGCGCGCGACCAGGCTG
CTGGGCGAGGCGGACGTGGT

Product: precorrin-3 methyltransferase / precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: Precorrin-2 C(20)-methyltransferase; S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT; Precorrin-3B C17-methyltransferase; S-adenosyl-L-methionine--precorrin-3B methyltransferase [H]

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MNGTFTVVGIGPGDPELMTLKAVRLIGDAQVVAFHAGVKKRSHARRIADSVIPAGAIEEELRYPVTTGTTDHPGGYVGAM
ADFYEECAVRLSAHLDAGRDVVLLAEGDPLFYGSSMYLHDRFKHAYDTAVVPGVPAFAAATAAVSTPLVRQTDVLTVLTG
TLPEPELARRLADTDGAIIMKLGRTFPAVRSALEQAGRLDGAWYVERASQAEERWLPVAEVDPDSVPYFSLVFVPGDTAQ
TPSAERMRVGLLDGGPVVAERPAAELLVVGLGPGPDGWLTPEAADALAGVDHVVGYGRYVERVPQRAGLTRHASGNTVEV
DRARAALDLARAGEKVAVVSGGDAGVFGMASAVFEAAEDPAYADVTIRVLPGLSAVQAVAARAGAPIGADFAVVSLSDRL
KPWEVVERRLRAIAEADLVLAIYNPSSRSRTGQLATARDVLLEHRKPDTVVIVGRDIGRAEESLVVTTLGDLDPATIDMK
CLLIVGATSTRVTRGRVWTPRFVKAGP

Sequences:

>Translated_507_residues
MNGTFTVVGIGPGDPELMTLKAVRLIGDAQVVAFHAGVKKRSHARRIADSVIPAGAIEEELRYPVTTGTTDHPGGYVGAM
ADFYEECAVRLSAHLDAGRDVVLLAEGDPLFYGSSMYLHDRFKHAYDTAVVPGVPAFAAATAAVSTPLVRQTDVLTVLTG
TLPEPELARRLADTDGAIIMKLGRTFPAVRSALEQAGRLDGAWYVERASQAEERWLPVAEVDPDSVPYFSLVFVPGDTAQ
TPSAERMRVGLLDGGPVVAERPAAELLVVGLGPGPDGWLTPEAADALAGVDHVVGYGRYVERVPQRAGLTRHASGNTVEV
DRARAALDLARAGEKVAVVSGGDAGVFGMASAVFEAAEDPAYADVTIRVLPGLSAVQAVAARAGAPIGADFAVVSLSDRL
KPWEVVERRLRAIAEADLVLAIYNPSSRSRTGQLATARDVLLEHRKPDTVVIVGRDIGRAEESLVVTTLGDLDPATIDMK
CLLIVGATSTRVTRGRVWTPRFVKAGP
>Mature_507_residues
MNGTFTVVGIGPGDPELMTLKAVRLIGDAQVVAFHAGVKKRSHARRIADSVIPAGAIEEELRYPVTTGTTDHPGGYVGAM
ADFYEECAVRLSAHLDAGRDVVLLAEGDPLFYGSSMYLHDRFKHAYDTAVVPGVPAFAAATAAVSTPLVRQTDVLTVLTG
TLPEPELARRLADTDGAIIMKLGRTFPAVRSALEQAGRLDGAWYVERASQAEERWLPVAEVDPDSVPYFSLVFVPGDTAQ
TPSAERMRVGLLDGGPVVAERPAAELLVVGLGPGPDGWLTPEAADALAGVDHVVGYGRYVERVPQRAGLTRHASGNTVEV
DRARAALDLARAGEKVAVVSGGDAGVFGMASAVFEAAEDPAYADVTIRVLPGLSAVQAVAARAGAPIGADFAVVSLSDRL
KPWEVVERRLRAIAEADLVLAIYNPSSRSRTGQLATARDVLLEHRKPDTVVIVGRDIGRAEESLVVTTLGDLDPATIDMK
CLLIVGATSTRVTRGRVWTPRFVKAGP

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR006364
- InterPro:   IPR006363
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130; =2.1.1.131 [H]

Molecular weight: Translated: 53599; Mature: 53599

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGTFTVVGIGPGDPELMTLKAVRLIGDAQVVAFHAGVKKRSHARRIADSVIPAGAIEEE
CCCEEEEEEECCCCCCEEEEEEHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHH
LRYPVTTGTTDHPGGYVGAMADFYEECAVRLSAHLDAGRDVVLLAEGDPLFYGSSMYLHD
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCEEHHHH
RFKHAYDTAVVPGVPAFAAATAAVSTPLVRQTDVLTVLTGTLPEPELARRLADTDGAIIM
HHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCEEEE
KLGRTFPAVRSALEQAGRLDGAWYVERASQAEERWLPVAEVDPDSVPYFSLVFVPGDTAQ
ECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
TPSAERMRVGLLDGGPVVAERPAAELLVVGLGPGPDGWLTPEAADALAGVDHVVGYGRYV
CCCCHHEEEEEECCCCCEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ERVPQRAGLTRHASGNTVEVDRARAALDLARAGEKVAVVSGGDAGVFGMASAVFEAAEDP
HHHHHHCCCEECCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCC
AYADVTIRVLPGLSAVQAVAARAGAPIGADFAVVSLSDRLKPWEVVERRLRAIAEADLVL
CEEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEE
AIYNPSSRSRTGQLATARDVLLEHRKPDTVVIVGRDIGRAEESLVVTTLGDLDPATIDMK
EEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCEECEE
CLLIVGATSTRVTRGRVWTPRFVKAGP
EEEEEECCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNGTFTVVGIGPGDPELMTLKAVRLIGDAQVVAFHAGVKKRSHARRIADSVIPAGAIEEE
CCCEEEEEEECCCCCCEEEEEEHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCHHH
LRYPVTTGTTDHPGGYVGAMADFYEECAVRLSAHLDAGRDVVLLAEGDPLFYGSSMYLHD
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCEEHHHH
RFKHAYDTAVVPGVPAFAAATAAVSTPLVRQTDVLTVLTGTLPEPELARRLADTDGAIIM
HHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCEEEE
KLGRTFPAVRSALEQAGRLDGAWYVERASQAEERWLPVAEVDPDSVPYFSLVFVPGDTAQ
ECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCC
TPSAERMRVGLLDGGPVVAERPAAELLVVGLGPGPDGWLTPEAADALAGVDHVVGYGRYV
CCCCHHEEEEEECCCCCEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ERVPQRAGLTRHASGNTVEVDRARAALDLARAGEKVAVVSGGDAGVFGMASAVFEAAEDP
HHHHHHCCCEECCCCCEEEEHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCC
AYADVTIRVLPGLSAVQAVAARAGAPIGADFAVVSLSDRLKPWEVVERRLRAIAEADLVL
CEEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEE
AIYNPSSRSRTGQLATARDVLLEHRKPDTVVIVGRDIGRAEESLVVTTLGDLDPATIDMK
EEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCEECEE
CLLIVGATSTRVTRGRVWTPRFVKAGP
EEEEEECCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]