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The map label for this gene is cobO [H]

Identifier: 119717112

GI number: 119717112

Start: 3071036

End: 3071650

Strand: Reverse

Name: cobO [H]

Synonym: Noca_2888

Alternate gene names: 119717112

Gene position: 3071650-3071036 (Counterclockwise)

Preceding gene: 119717113

Following gene: 119717111

Centisome position: 61.61

GC content: 68.46

Gene sequence:

>615_bases
ATGCCCCAGGGAGTTCCCACCGCCGTTCCCGACGACGGCCTCACCACACGCCAGCGCCGCAACCGGCCGTTGCTGATCGT
CCACACCGGCGAGAACAAGGGCAAGTCCACGGCCGCCTTCGGGCTCGGTCTGCGGGGGTGGAACCAGGGCTGGAACGTTG
CGGTCTTCCAGTTCGTGAAGTCGGCGAAGTGGAAGGTCGGCGAGGAGACCGCCTACCTCGCGCTCAACCGCGTGCACGAG
CAGACCGGCCAGGGCGGCCCGGTGCAGTGGAACAAGATGGGCGACGGTTGGTCCTGGTCGCGCAAGAAGGGCGAGGACGA
GGACCACGCCCAGGTCGCCCGCGACGGCTGGGCCGAGATCAAGCGCCGCATCCTCGCCGAGGAGCACGACCTCTACGTCC
TCGACGAGTTCGCCTACCCGGTGAAGTGGGGCTGGATCGACGCCGCCGAGGTCGCCGACTTCCTGGCGAGCCGGCCCGGT
CACCAGCACGTCGTCATCACCGGCCGCGACGTCGCCCCGGAGATCATCGAGGTCGCCGACCTCGTCACCGAGATGACGAA
GATCAAGCACCCGATGGACGCCGGCCAGAAGGGCCAGAAGGGCATCGAGTGGTGA

Upstream 100 bases:

>100_bases
TCGCGATCGGGCTGGCGCGAAGCCTCAACGCGGAGCACGTCCCCGTCGCCGAGGTCAGCGCCGAGGCGCTGACCAGAACC
GTCACCAGGAAGGTCGCCTG

Downstream 100 bases:

>100_bases
GGCTGCCCCGCCTCGTGGTGGCGGCGCCATCGACCGGTCAAGGCAAGACGACCGTCGCGACGGGGCTGATGGCGGCCCTG
CGCATCTCCGGCCACGAGGT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MPQGVPTAVPDDGLTTRQRRNRPLLIVHTGENKGKSTAAFGLGLRGWNQGWNVAVFQFVKSAKWKVGEETAYLALNRVHE
QTGQGGPVQWNKMGDGWSWSRKKGEDEDHAQVARDGWAEIKRRILAEEHDLYVLDEFAYPVKWGWIDAAEVADFLASRPG
HQHVVITGRDVAPEIIEVADLVTEMTKIKHPMDAGQKGQKGIEW

Sequences:

>Translated_204_residues
MPQGVPTAVPDDGLTTRQRRNRPLLIVHTGENKGKSTAAFGLGLRGWNQGWNVAVFQFVKSAKWKVGEETAYLALNRVHE
QTGQGGPVQWNKMGDGWSWSRKKGEDEDHAQVARDGWAEIKRRILAEEHDLYVLDEFAYPVKWGWIDAAEVADFLASRPG
HQHVVITGRDVAPEIIEVADLVTEMTKIKHPMDAGQKGQKGIEW
>Mature_203_residues
PQGVPTAVPDDGLTTRQRRNRPLLIVHTGENKGKSTAAFGLGLRGWNQGWNVAVFQFVKSAKWKVGEETAYLALNRVHEQ
TGQGGPVQWNKMGDGWSWSRKKGEDEDHAQVARDGWAEIKRRILAEEHDLYVLDEFAYPVKWGWIDAAEVADFLASRPGH
QHVVITGRDVAPEIIEVADLVTEMTKIKHPMDAGQKGQKGIEW

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=193, Percent_Identity=35.2331606217617, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22873; Mature: 22742

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGVPTAVPDDGLTTRQRRNRPLLIVHTGENKGKSTAAFGLGLRGWNQGWNVAVFQFVK
CCCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHH
SAKWKVGEETAYLALNRVHEQTGQGGPVQWNKMGDGWSWSRKKGEDEDHAQVARDGWAEI
HHCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KRRILAEEHDLYVLDEFAYPVKWGWIDAAEVADFLASRPGHQHVVITGRDVAPEIIEVAD
HHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
LVTEMTKIKHPMDAGQKGQKGIEW
HHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQGVPTAVPDDGLTTRQRRNRPLLIVHTGENKGKSTAAFGLGLRGWNQGWNVAVFQFVK
CCCCCCCCCCCCCCCHHHCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCHHHHHHHH
SAKWKVGEETAYLALNRVHEQTGQGGPVQWNKMGDGWSWSRKKGEDEDHAQVARDGWAEI
HHCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KRRILAEEHDLYVLDEFAYPVKWGWIDAAEVADFLASRPGHQHVVITGRDVAPEIIEVAD
HHHHHHCCCCEEEEECCCCCEEECCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
LVTEMTKIKHPMDAGQKGQKGIEW
HHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]