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The map label for this gene is corA [H]

Identifier: 119716849

GI number: 119716849

Start: 2793021

End: 2793992

Strand: Reverse

Name: corA [H]

Synonym: Noca_2624

Alternate gene names: 119716849

Gene position: 2793992-2793021 (Counterclockwise)

Preceding gene: 119716855

Following gene: 119716847

Centisome position: 56.04

GC content: 69.24

Gene sequence:

>972_bases
GTGATCGTCGACTGCGCCCTGTACCGCGACGGCAGGCGGGTCGAGGGCGGCACCCACTGGCGGGAGCTGCGGGCGAAGGC
GGACGCGGACGGCGACTTCATCTGGATCGGGATGCACGAACCCACGCACGACGAGGTGCACGAGGTCGCCGAGGTGTTCG
GGCTCCACCAGCTCGCGGTCGAGGACGCCGTGAAGGCGCACCAGCGGCCGAAGCTGGAGCGGTTCGACGACATGGTGTTC
CTGATCCTCAAGACGCTGTGGTACGTCGACGAGCAGGACGCGGTCGAGACCGGCGAGATCGCGATGTTCGTCGGCGCGGA
CTTCGTCGTCTCCGTCCGCCACGGTCAGGGCAACGAGCTGCACTCGGCCCGCGCGGAGCTGGAGTCGAGCAGGAGGGTGC
TCAGCCACGGCCCGGGCGGGGTGCTGTACGCGGTGATCGACCGGGTCGTGGACGAGTACCTCGACGTCGTCGACGAGCTG
GTCGTCGACGTGGACGAGATCGAGGCGTCGGTGTTCTCCGACGACCGCACCAACGACTCCGCCCGCATCTACGTGCTCAA
GCGGGAGATCGCGGAGGTACGCCGCGCGGTGCTGCCGCTGCGGGACCCGATGACCCGGCTGGCCGCCGGGACGGTCACCG
GGATCCCGGAGGAGGCGGCGCCGTTCTTCCGCGATGTCGGCGACCACCTGGCCCGGGCGGCGGAGACCGTGGACACCCTG
GACACCCTGCTCTCGACGGCGTTCGACGCCCACCTCGCCCAGATCTCGGTGCAGCAGAACAACGACATGCGCAAGATCTC
CGCAGGAGCCGCACTGGTGGTCGTGCCGACCCTGATCGCCGGGGTCTACGGCATGAACTTCCGGCACATGCCCGAGCTCG
ACTGGACCTACGGCTACCCGTTCGCGCTCGCGCTGATGGCGGCGGTCGCCCTGGGGCTGTGGGTGCTGTTCAAGAAGTCC
GGGTGGTTGTAG

Upstream 100 bases:

>100_bases
CGGCCGGTCAGGGTACCCGCGGCGTTCGCCGTCGTCCGACCGTGTCGGACGAGGATCACGGTTGCCATGCGGTGGACTGT
AGTGGGGCTACCGTGGGCGC

Downstream 100 bases:

>100_bases
GGGCCGAGGCCGGCCAGCCCCGCTGGCGCATCTGCGCTACGCCGCGATCACGCCGGTCGCGACCAGGACCAGCGTCGCCG
CACCGAGGGCCACGCGGTAC

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MIVDCALYRDGRRVEGGTHWRELRAKADADGDFIWIGMHEPTHDEVHEVAEVFGLHQLAVEDAVKAHQRPKLERFDDMVF
LILKTLWYVDEQDAVETGEIAMFVGADFVVSVRHGQGNELHSARAELESSRRVLSHGPGGVLYAVIDRVVDEYLDVVDEL
VVDVDEIEASVFSDDRTNDSARIYVLKREIAEVRRAVLPLRDPMTRLAAGTVTGIPEEAAPFFRDVGDHLARAAETVDTL
DTLLSTAFDAHLAQISVQQNNDMRKISAGAALVVVPTLIAGVYGMNFRHMPELDWTYGYPFALALMAAVALGLWVLFKKS
GWL

Sequences:

>Translated_323_residues
MIVDCALYRDGRRVEGGTHWRELRAKADADGDFIWIGMHEPTHDEVHEVAEVFGLHQLAVEDAVKAHQRPKLERFDDMVF
LILKTLWYVDEQDAVETGEIAMFVGADFVVSVRHGQGNELHSARAELESSRRVLSHGPGGVLYAVIDRVVDEYLDVVDEL
VVDVDEIEASVFSDDRTNDSARIYVLKREIAEVRRAVLPLRDPMTRLAAGTVTGIPEEAAPFFRDVGDHLARAAETVDTL
DTLLSTAFDAHLAQISVQQNNDMRKISAGAALVVVPTLIAGVYGMNFRHMPELDWTYGYPFALALMAAVALGLWVLFKKS
GWL
>Mature_323_residues
MIVDCALYRDGRRVEGGTHWRELRAKADADGDFIWIGMHEPTHDEVHEVAEVFGLHQLAVEDAVKAHQRPKLERFDDMVF
LILKTLWYVDEQDAVETGEIAMFVGADFVVSVRHGQGNELHSARAELESSRRVLSHGPGGVLYAVIDRVVDEYLDVVDEL
VVDVDEIEASVFSDDRTNDSARIYVLKREIAEVRRAVLPLRDPMTRLAAGTVTGIPEEAAPFFRDVGDHLARAAETVDTL
DTLLSTAFDAHLAQISVQQNNDMRKISAGAALVVVPTLIAGVYGMNFRHMPELDWTYGYPFALALMAAVALGLWVLFKKS
GWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=306, Percent_Identity=24.5098039215686, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787604, Length=296, Percent_Identity=21.6216216216216, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 35981; Mature: 35981

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDCALYRDGRRVEGGTHWRELRAKADADGDFIWIGMHEPTHDEVHEVAEVFGLHQLAV
CEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
EDAVKAHQRPKLERFDDMVFLILKTLWYVDEQDAVETGEIAMFVGADFVVSVRHGQGNEL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCHH
HSARAELESSRRVLSHGPGGVLYAVIDRVVDEYLDVVDELVVDVDEIEASVFSDDRTNDS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARIYVLKREIAEVRRAVLPLRDPMTRLAAGTVTGIPEEAAPFFRDVGDHLARAAETVDTL
EEEEEHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTLLSTAFDAHLAQISVQQNNDMRKISAGAALVVVPTLIAGVYGMNFRHMPELDWTYGYP
HHHHHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
FALALMAAVALGLWVLFKKSGWL
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIVDCALYRDGRRVEGGTHWRELRAKADADGDFIWIGMHEPTHDEVHEVAEVFGLHQLAV
CEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
EDAVKAHQRPKLERFDDMVFLILKTLWYVDEQDAVETGEIAMFVGADFVVSVRHGQGNEL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCHH
HSARAELESSRRVLSHGPGGVLYAVIDRVVDEYLDVVDELVVDVDEIEASVFSDDRTNDS
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ARIYVLKREIAEVRRAVLPLRDPMTRLAAGTVTGIPEEAAPFFRDVGDHLARAAETVDTL
EEEEEHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DTLLSTAFDAHLAQISVQQNNDMRKISAGAALVVVPTLIAGVYGMNFRHMPELDWTYGYP
HHHHHHHHHHHHHHEEECCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
FALALMAAVALGLWVLFKKSGWL
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]