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The map label for this gene is yajO [H]

Identifier: 119716847

GI number: 119716847

Start: 2791139

End: 2792086

Strand: Reverse

Name: yajO [H]

Synonym: Noca_2622

Alternate gene names: 119716847

Gene position: 2792086-2791139 (Counterclockwise)

Preceding gene: 119716849

Following gene: 119716846

Centisome position: 56.0

GC content: 74.37

Gene sequence:

>948_bases
ATGCAGCAGCGGCGTGTCGGCGCGACCGGCCTCACCGTGTCCCGTCTGGCGCTCGGCACGATGACGTGGGGACGCGACAC
CGACGAGCACGAGGCGCGCGACCAGCTGGTCGCGTTCACCGAGGCCGGCGGCACGCTGGTCGACACCGCGGCCGGCTACG
GCAACGGTGCGTCCGAGGAGCTGATCGGCACCCTCATCGGCGACGTCGTCGCCCGCGACGACGTCGTGCTCGCCACCAAG
GCCGGGATCACCGCCCGGCGAGGTGGCCGTGAGTACAACACCTCACGCGGCCACCTGCTCGCCACCCTCGACGCCTCCCT
CCGCCGCCTCGGGGTCGCCCATGTCGACCTCTGGCAGGTGCACATCTGGTCCGACGAGGCGCCGCTCGAGGAGACCCTCG
CGGCGCTGGACACCGCCGTGCAGAGCGGGCGGGCGTCGTACGTCGGCGTCTCGAACTACTCGGGTTGGCAGACGGCCCAA
GCGGCGACCTGGCAACGGGCGGTGCCGGGGCGCACCCCGCTGGCGAGCACCCAGGTGGAGTACTCCCTGCTCAACCGGGT
CGCCGAGCACGAGGTGCTCCCGGCGGCCGCCGCGCTCGGGCTCGGCGTGCTGCCGTGGTCGCCGCTCGGTCGCGGCGTGC
TGACCGGCAAGTACCGCACCGGCACCCCCTCGGACTCCCGCGCGGCCTCCGCGCACTTCGCGAACTTCGTCAGCCCCTAC
CTCGACGAGCGGTCCGGGGGCATCGTCGAGGCCGTCGCCCGGGCCGCGGACGGCCTCGGCTGGACGCCGCTCGAGGTCGC
GTTGGCGTGGGTCCGCGACCGACCGGGCGTCACGGCCCCCGTTGTCGGTGCCCGTACCGCTGCCCAGCTGCGCGGAGCCC
TCGGCGTCGAGGAGCTGAGCCTGCCCGCCGAGATCACCGCCGCCCTGGACGACGTGTCCGCCGATTGA

Upstream 100 bases:

>100_bases
CACGAGGGCCTGGAGGAAGTCCACCACGGCGGGAACTCTACGGGCGGCCGCTGGGCGTGCCGGTGCAGGGCCGCGTGGAG
TCGCCGACTACCTTGTCGCC

Downstream 100 bases:

>100_bases
CCCCTGTCCGACCGCTGACGAGACGGAGACCAGATGAGCCGAGAGCTGCGTAGGCCCCCCGCTCGTGGTGTCGAGTGGGA
GTTCGACAAGGTGACCTTCT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQQRRVGATGLTVSRLALGTMTWGRDTDEHEARDQLVAFTEAGGTLVDTAAGYGNGASEELIGTLIGDVVARDDVVLATK
AGITARRGGREYNTSRGHLLATLDASLRRLGVAHVDLWQVHIWSDEAPLEETLAALDTAVQSGRASYVGVSNYSGWQTAQ
AATWQRAVPGRTPLASTQVEYSLLNRVAEHEVLPAAAALGLGVLPWSPLGRGVLTGKYRTGTPSDSRAASAHFANFVSPY
LDERSGGIVEAVARAADGLGWTPLEVALAWVRDRPGVTAPVVGARTAAQLRGALGVEELSLPAEITAALDDVSAD

Sequences:

>Translated_315_residues
MQQRRVGATGLTVSRLALGTMTWGRDTDEHEARDQLVAFTEAGGTLVDTAAGYGNGASEELIGTLIGDVVARDDVVLATK
AGITARRGGREYNTSRGHLLATLDASLRRLGVAHVDLWQVHIWSDEAPLEETLAALDTAVQSGRASYVGVSNYSGWQTAQ
AATWQRAVPGRTPLASTQVEYSLLNRVAEHEVLPAAAALGLGVLPWSPLGRGVLTGKYRTGTPSDSRAASAHFANFVSPY
LDERSGGIVEAVARAADGLGWTPLEVALAWVRDRPGVTAPVVGARTAAQLRGALGVEELSLPAEITAALDDVSAD
>Mature_315_residues
MQQRRVGATGLTVSRLALGTMTWGRDTDEHEARDQLVAFTEAGGTLVDTAAGYGNGASEELIGTLIGDVVARDDVVLATK
AGITARRGGREYNTSRGHLLATLDASLRRLGVAHVDLWQVHIWSDEAPLEETLAALDTAVQSGRASYVGVSNYSGWQTAQ
AATWQRAVPGRTPLASTQVEYSLLNRVAEHEVLPAAAALGLGVLPWSPLGRGVLTGKYRTGTPSDSRAASAHFANFVSPY
LDERSGGIVEAVARAADGLGWTPLEVALAWVRDRPGVTAPVVGARTAAQLRGALGVEELSLPAEITAALDDVSAD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=319, Percent_Identity=29.7805642633229, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI27436964, Length=318, Percent_Identity=29.559748427673, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4504825, Length=316, Percent_Identity=29.746835443038, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=29.559748427673, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=29.559748427673, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI27436971, Length=300, Percent_Identity=28.6666666666667, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI223718702, Length=211, Percent_Identity=34.5971563981043, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI41327764, Length=219, Percent_Identity=32.4200913242009, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41152114, Length=218, Percent_Identity=30.7339449541284, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI223718708, Length=159, Percent_Identity=34.5911949685535, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081735, Length=318, Percent_Identity=37.1069182389937, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=33.641975308642, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789199, Length=343, Percent_Identity=30.0291545189504, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=27.4096385542169, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788081, Length=316, Percent_Identity=28.7974683544304, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994888, Length=312, Percent_Identity=27.2435897435897, Blast_Score=68, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=27.0348837209302, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=28.4375, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=28.8135593220339, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319951, Length=320, Percent_Identity=27.1875, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=26.8, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646159, Length=226, Percent_Identity=30.5309734513274, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640980, Length=318, Percent_Identity=25.7861635220126, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45549126, Length=318, Percent_Identity=25.7861635220126, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24646155, Length=229, Percent_Identity=28.82096069869, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33070; Mature: 33070

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRRVGATGLTVSRLALGTMTWGRDTDEHEARDQLVAFTEAGGTLVDTAAGYGNGASEE
CCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHEEEEECCCCEEEECCCCCCCCCHHH
LIGTLIGDVVARDDVVLATKAGITARRGGREYNTSRGHLLATLDASLRRLGVAHVDLWQV
HHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCEEEEEEE
HIWSDEAPLEETLAALDTAVQSGRASYVGVSNYSGWQTAQAATWQRAVPGRTPLASTQVE
EEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
YSLLNRVAEHEVLPAAAALGLGVLPWSPLGRGVLTGKYRTGTPSDSRAASAHFANFVSPY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHH
LDERSGGIVEAVARAADGLGWTPLEVALAWVRDRPGVTAPVVGARTAAQLRGALGVEELS
HHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHC
LPAEITAALDDVSAD
CCHHHHHHHHHCCCC
>Mature Secondary Structure
MQQRRVGATGLTVSRLALGTMTWGRDTDEHEARDQLVAFTEAGGTLVDTAAGYGNGASEE
CCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHEEEEECCCCEEEECCCCCCCCCHHH
LIGTLIGDVVARDDVVLATKAGITARRGGREYNTSRGHLLATLDASLRRLGVAHVDLWQV
HHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCCCCCCCEEEEHHHHHHHHCCCEEEEEEE
HIWSDEAPLEETLAALDTAVQSGRASYVGVSNYSGWQTAQAATWQRAVPGRTPLASTQVE
EEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
YSLLNRVAEHEVLPAAAALGLGVLPWSPLGRGVLTGKYRTGTPSDSRAASAHFANFVSPY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHH
LDERSGGIVEAVARAADGLGWTPLEVALAWVRDRPGVTAPVVGARTAAQLRGALGVEELS
HHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCHHHHC
LPAEITAALDDVSAD
CCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]