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The map label for this gene is serB [H]

Identifier: 119716800

GI number: 119716800

Start: 2740788

End: 2742050

Strand: Reverse

Name: serB [H]

Synonym: Noca_2574

Alternate gene names: 119716800

Gene position: 2742050-2740788 (Counterclockwise)

Preceding gene: 119716801

Following gene: 119716795

Centisome position: 55.0

GC content: 72.84

Gene sequence:

>1263_bases
ATGAGGTCGGCCGCCGCGATAGCCTCGGCGACTGACATGACTAACGCGCAGGCCGGCCGCAAGCCGGAGACCCTCCTCAT
CACGCTGACCGGCAAGGACCGCCCCGGCGTGACGTCCTCGGTGTTCGCCACGCTCTCCGGGGCCGGCGTGGAGGTCGTCG
ACATCGAGCAGATCGTGCTGCGCGGCCGGCTCATCCTCGGCGTCCTCGTCACCGCACCCCACCACCCGCGCCGGGTGACG
GAGGCGGTCCAGGAGACTGCGGCGGCCCTCGGCATGAGCGTGGACGTCGAGCGGGGCGTGGGCGACAACAAGGCGCGGCG
GGGCGGCCGCTCGCACGTGACGATCATCGGCTCCCCGCTGCGAGCTGCGGCGATGGGCGCGATCGCCGGCCGGATCGCCG
ACGCCGGCGCCAACATCGACCGGATCGAGCGGATGGCCCGCTACCCGGTCACGGCGATCGACCTGCACGTCTCCGGGGTC
GACACCGCGGCGCTGCGCACCGTGCTCGCAGCCGAGGCGTCCCGGCAGGGCGTCGACATCGCGGTGCAGCCGGCGAACCT
CCTGCGGCGAGGTGCCCGCCTGATCGTGATGGACGTCGACTCCACCCTGATCCAGGGCGAGGTGATCGAGATGCTGGCCG
CGCACGCCGGGTGCGAGGCGGAGGTCGCGCGGGTCACCGAGGCCGCGATGCGCGGTGAGATCGACTTCGAGGCCTCGCTG
CGAGCGCGAGTGGCCCTGCTCGAAGGAGTCCCGGCGAGCGCGCTCGACGAGGTGTACGACGCCATCCTGCTCGCCCCCGG
CGCGCGCACGATGGTGCGCACCCTGCGCCGGCTCGGCTACCACTTCGCGATCGTCTCCGGAGGGTTCAGCCAGATCACCG
ACCGGCTGGCCACCGACCTCGGCATCGACTACTCCCGGGCCAACGAGCTGGAGATCGTCGACGGACGCCTGACGGGCCGG
ATCGTCGGTCCGGTCGTCGACCGCGCCGGCAAGGCCGCTGCGCTGCGGGAGTTCGCGGCCACCGCGGGCGTCGCGGAGGC
CGCGGTGATCGCCATCGGCGACGGCGCCAACGACCTGGACATGCTCAACGCGGCGGGCCTCGGCATCGCCTACAACGCGA
AGCCGCTGGTGCGCGACGCCGCCGACACCGCGGTGAACGTGCCCTACCTCGACGCGATCCTCTATCTCCTCGGCATCTCC
CGCGAGGAGATCGAGGCCGCCGACGCCGAGGCGGGCTTCGTCACCCCGGCACCGCCGGTCTGA

Upstream 100 bases:

>100_bases
CGTACGAGATCGCGGAGCGCCGCGGTGCCCTGGTGTCGCTCGCGCGCGCTGGCCGGCGGGCCCTGGTAGCGGCCTGCTCA
CCGGAGGCGTGGCCTCCGGC

Downstream 100 bases:

>100_bases
GGTCCGGGCCGGGCGTCAGCCGCGGCCGACGTGGAAGGCCACGAGGCGGGCGCTGGCGCCGGCGAGATCGGCCCAGGCGC
CGTCGTACTCGAAGACCGCC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MRSAAAIASATDMTNAQAGRKPETLLITLTGKDRPGVTSSVFATLSGAGVEVVDIEQIVLRGRLILGVLVTAPHHPRRVT
EAVQETAAALGMSVDVERGVGDNKARRGGRSHVTIIGSPLRAAAMGAIAGRIADAGANIDRIERMARYPVTAIDLHVSGV
DTAALRTVLAAEASRQGVDIAVQPANLLRRGARLIVMDVDSTLIQGEVIEMLAAHAGCEAEVARVTEAAMRGEIDFEASL
RARVALLEGVPASALDEVYDAILLAPGARTMVRTLRRLGYHFAIVSGGFSQITDRLATDLGIDYSRANELEIVDGRLTGR
IVGPVVDRAGKAAALREFAATAGVAEAAVIAIGDGANDLDMLNAAGLGIAYNAKPLVRDAADTAVNVPYLDAILYLLGIS
REEIEAADAEAGFVTPAPPV

Sequences:

>Translated_420_residues
MRSAAAIASATDMTNAQAGRKPETLLITLTGKDRPGVTSSVFATLSGAGVEVVDIEQIVLRGRLILGVLVTAPHHPRRVT
EAVQETAAALGMSVDVERGVGDNKARRGGRSHVTIIGSPLRAAAMGAIAGRIADAGANIDRIERMARYPVTAIDLHVSGV
DTAALRTVLAAEASRQGVDIAVQPANLLRRGARLIVMDVDSTLIQGEVIEMLAAHAGCEAEVARVTEAAMRGEIDFEASL
RARVALLEGVPASALDEVYDAILLAPGARTMVRTLRRLGYHFAIVSGGFSQITDRLATDLGIDYSRANELEIVDGRLTGR
IVGPVVDRAGKAAALREFAATAGVAEAAVIAIGDGANDLDMLNAAGLGIAYNAKPLVRDAADTAVNVPYLDAILYLLGIS
REEIEAADAEAGFVTPAPPV
>Mature_420_residues
MRSAAAIASATDMTNAQAGRKPETLLITLTGKDRPGVTSSVFATLSGAGVEVVDIEQIVLRGRLILGVLVTAPHHPRRVT
EAVQETAAALGMSVDVERGVGDNKARRGGRSHVTIIGSPLRAAAMGAIAGRIADAGANIDRIERMARYPVTAIDLHVSGV
DTAALRTVLAAEASRQGVDIAVQPANLLRRGARLIVMDVDSTLIQGEVIEMLAAHAGCEAEVARVTEAAMRGEIDFEASL
RARVALLEGVPASALDEVYDAILLAPGARTMVRTLRRLGYHFAIVSGGFSQITDRLATDLGIDYSRANELEIVDGRLTGR
IVGPVVDRAGKAAALREFAATAGVAEAAVIAIGDGANDLDMLNAAGLGIAYNAKPLVRDAADTAVNVPYLDAILYLLGIS
REEIEAADAEAGFVTPAPPV

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=216, Percent_Identity=28.7037037037037, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790849, Length=192, Percent_Identity=48.9583333333333, Blast_Score=168, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI115534454, Length=181, Percent_Identity=32.5966850828729, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115534456, Length=181, Percent_Identity=32.5966850828729, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=233, Percent_Identity=41.2017167381974, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24661601, Length=185, Percent_Identity=28.1081081081081, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 43711; Mature: 43711

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAAAIASATDMTNAQAGRKPETLLITLTGKDRPGVTSSVFATLSGAGVEVVDIEQIVL
CCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHH
RGRLILGVLVTAPHHPRRVTEAVQETAAALGMSVDVERGVGDNKARRGGRSHVTIIGSPL
HHHHHEEHEECCCCCHHHHHHHHHHHHHHHCCCEEHHCCCCCCHHHCCCCCEEEEEECCH
RAAAMGAIAGRIADAGANIDRIERMARYPVTAIDLHVSGVDTAALRTVLAAEASRQGVDI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEE
AVQPANLLRRGARLIVMDVDSTLIQGEVIEMLAAHAGCEAEVARVTEAAMRGEIDFEASL
EEECHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
RARVALLEGVPASALDEVYDAILLAPGARTMVRTLRRLGYHFAIVSGGFSQITDRLATDL
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHC
GIDYSRANELEIVDGRLTGRIVGPVVDRAGKAAALREFAATAGVAEAAVIAIGDGANDLD
CCCCCCCCCEEEECCCCCCEEHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
MLNAAGLGIAYNAKPLVRDAADTAVNVPYLDAILYLLGISREEIEAADAEAGFVTPAPPV
HHHHCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSAAAIASATDMTNAQAGRKPETLLITLTGKDRPGVTSSVFATLSGAGVEVVDIEQIVL
CCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEEHHHHHH
RGRLILGVLVTAPHHPRRVTEAVQETAAALGMSVDVERGVGDNKARRGGRSHVTIIGSPL
HHHHHEEHEECCCCCHHHHHHHHHHHHHHHCCCEEHHCCCCCCHHHCCCCCEEEEEECCH
RAAAMGAIAGRIADAGANIDRIERMARYPVTAIDLHVSGVDTAALRTVLAAEASRQGVDI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEE
AVQPANLLRRGARLIVMDVDSTLIQGEVIEMLAAHAGCEAEVARVTEAAMRGEIDFEASL
EEECHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
RARVALLEGVPASALDEVYDAILLAPGARTMVRTLRRLGYHFAIVSGGFSQITDRLATDL
HHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHC
GIDYSRANELEIVDGRLTGRIVGPVVDRAGKAAALREFAATAGVAEAAVIAIGDGANDLD
CCCCCCCCCEEEECCCCCCEEHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
MLNAAGLGIAYNAKPLVRDAADTAVNVPYLDAILYLLGISREEIEAADAEAGFVTPAPPV
HHHHCCCCEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA