Click here to switch to the map view.

The map label for this gene is lipB [H]

Identifier: 119716527

GI number: 119716527

Start: 2450068

End: 2450775

Strand: Reverse

Name: lipB [H]

Synonym: Noca_2300

Alternate gene names: 119716527

Gene position: 2450775-2450068 (Counterclockwise)

Preceding gene: 119716529

Following gene: 119716526

Centisome position: 49.15

GC content: 74.44

Gene sequence:

>708_bases
ATGGTCGAGTACGTCGCCGCGTGGGACCTGCAGCGCGAGGTGCACCAGCAGGTCGCGGACGGCAACGAGCCGGACACCGT
GCTGCTGCTCGAGCACCCGCCGGTCTTCACCGCCGGGAAGCGCACCGAGCCGCACGAGCGGCCGGCCGACCCGGGCGGCG
CGCCGGTCATCGACGTCGACCGCGGCGGCAAGATCACCTTCCACGGCCCCGGCCAGCTGGTCGGCTACCCGATCGTCACC
CTGCCCGACCACGTGCTGGTCGTCGACTACGTGCGCCGGCTCGAGGAGGCGCTGATCCGGGCGTGCGCCGACCTGGGCGT
CACCACCGCCCGGGTGCCGGGCCGCAGCGGCGTCTGGCTCAAGGCCGAGCCCGGGAGGTCCGAGGGCGGCGGAGCCCCCC
TCGGGGAGCGCAAGGTCGCGGCGATCGGCATCCGGGTCAGCCGCGGCGTGACCATGCACGGGTTCGCCCTCAACTGCGAC
GTCGACCTCGGGTGGTACGACCGGTTCGTCCCCTGCGGGATCGCGGACGCAGGCGTCACCTCGCTGAGCCGCGAGCTCGG
TCGCGACGTCAGCGTGGCCGAGGCGACGCCGTACGTCGAGCGGCGGCTGCGCGAGTACCTCGCCTGGGCGCCGTACGACC
CCACGCCCGACTACGAGCCGCGCCCCGACCCGGCCAAGCAGCCGCGGATCGAGCTGCTCACTCCCTGA

Upstream 100 bases:

>100_bases
GAGCGGCATGGTCCTCTCCTACCCCGACCGGTGCCCCGGGCCCGCCGTCGTCCACAGGGCGCGCAGTAGGCTCGAGCGCG
TGAAGCTCCAAGACGTCGGG

Downstream 100 bases:

>100_bases
GGCGGGACCGCCTCCACCCGCCGCGTACAGTTGGCCAACGTGACGCAAGCTCCCCCCTCCCCACAAGCAGAGGGCCGCAA
GCTGCTCCGGCTCGAGGCAC

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MVEYVAAWDLQREVHQQVADGNEPDTVLLLEHPPVFTAGKRTEPHERPADPGGAPVIDVDRGGKITFHGPGQLVGYPIVT
LPDHVLVVDYVRRLEEALIRACADLGVTTARVPGRSGVWLKAEPGRSEGGGAPLGERKVAAIGIRVSRGVTMHGFALNCD
VDLGWYDRFVPCGIADAGVTSLSRELGRDVSVAEATPYVERRLREYLAWAPYDPTPDYEPRPDPAKQPRIELLTP

Sequences:

>Translated_235_residues
MVEYVAAWDLQREVHQQVADGNEPDTVLLLEHPPVFTAGKRTEPHERPADPGGAPVIDVDRGGKITFHGPGQLVGYPIVT
LPDHVLVVDYVRRLEEALIRACADLGVTTARVPGRSGVWLKAEPGRSEGGGAPLGERKVAAIGIRVSRGVTMHGFALNCD
VDLGWYDRFVPCGIADAGVTSLSRELGRDVSVAEATPYVERRLREYLAWAPYDPTPDYEPRPDPAKQPRIELLTP
>Mature_235_residues
MVEYVAAWDLQREVHQQVADGNEPDTVLLLEHPPVFTAGKRTEPHERPADPGGAPVIDVDRGGKITFHGPGQLVGYPIVT
LPDHVLVVDYVRRLEEALIRACADLGVTTARVPGRSGVWLKAEPGRSEGGGAPLGERKVAAIGIRVSRGVTMHGFALNCD
VDLGWYDRFVPCGIADAGVTSLSRELGRDVSVAEATPYVERRLREYLAWAPYDPTPDYEPRPDPAKQPRIELLTP

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family [H]

Homologues:

Organism=Homo sapiens, GI221554520, Length=195, Percent_Identity=41.025641025641, Blast_Score=114, Evalue=7e-26,
Organism=Escherichia coli, GI87081767, Length=166, Percent_Identity=36.7469879518072, Blast_Score=106, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323268, Length=188, Percent_Identity=29.2553191489362, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355483, Length=203, Percent_Identity=40.3940886699507, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 25641; Mature: 25641

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01313 LIPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEYVAAWDLQREVHQQVADGNEPDTVLLLEHPPVFTAGKRTEPHERPADPGGAPVIDVD
CCCEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCCCEEEEC
RGGKITFHGPGQLVGYPIVTLPDHVLVVDYVRRLEEALIRACADLGVTTARVPGRSGVWL
CCCEEEECCCCCEECEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
KAEPGRSEGGGAPLGERKVAAIGIRVSRGVTMHGFALNCDVDLGWYDRFVPCGIADAGVT
EECCCCCCCCCCCCCCCEEEEEEEEEECCCEEEEEEEEEEEECCHHHCCCCCCCCHHHHH
SLSRELGRDVSVAEATPYVERRLREYLAWAPYDPTPDYEPRPDPAKQPRIELLTP
HHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MVEYVAAWDLQREVHQQVADGNEPDTVLLLEHPPVFTAGKRTEPHERPADPGGAPVIDVD
CCCEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCCCCCCCCCEEEEC
RGGKITFHGPGQLVGYPIVTLPDHVLVVDYVRRLEEALIRACADLGVTTARVPGRSGVWL
CCCEEEECCCCCEECEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEE
KAEPGRSEGGGAPLGERKVAAIGIRVSRGVTMHGFALNCDVDLGWYDRFVPCGIADAGVT
EECCCCCCCCCCCCCCCEEEEEEEEEECCCEEEEEEEEEEEECCHHHCCCCCCCCHHHHH
SLSRELGRDVSVAEATPYVERRLREYLAWAPYDPTPDYEPRPDPAKQPRIELLTP
HHHHHHCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA