Click here to switch to the map view.

The map label for this gene is yegE [C]

Identifier: 119715375

GI number: 119715375

Start: 1204275

End: 1206440

Strand: Direct

Name: yegE [C]

Synonym: Noca_1137

Alternate gene names: 119715375

Gene position: 1204275-1206440 (Clockwise)

Preceding gene: 119715374

Following gene: 119715378

Centisome position: 24.15

GC content: 74.05

Gene sequence:

>2166_bases
ATGACGGGGAAGGGTGCGGCGCTCGGTGAGCCGCTGGTACCACTCGCCTCGAGGACGGACGGTCTCCTGGCCAGTCCGCC
GCCGTCCGGGGGAATGATGCGCGAGATCGACCAGGGCCAGCTGTTGGCGAGCATCGCCGCGACCTCCCACGACTGCATCC
TCTCCCTCGACTCCGACGCCAGGATCCGGTGGGCGAGCCCGGCGACCGAGCAGGTCCTCGGCTGGCGCCCCGACGACCTG
GCCGGCTGCGAGCTCGGCGTGTTGTTCCCCCGCGACGGCAGCGAGCTGCGCGACGCCACGGTCGCCCGGCTGCTCACCGG
CGAGCAGGTCGAGCCGTTCATCGACGCCGGCGTCCGTCGCGACGGCTCCTCGTTCAAGGCGCAGGTCACCCTCGGCCCGG
TACACGGCCCCGGGGACGAGATCACCGGGGTGATCCTGATCCTGCGCGACGTGACCGCCCAGCTGCACGAGCAGCGCGAG
CTGGCGCTCGCCCTCGAGATGTCCCGCGCACACTTCGACCAGGCGACCACGGCGCAGGCGATCCTCGACCTGAGCGGCCG
CCTCGAGTCGGTCAACCCCGCATGGTGCGACCTGTTCGGCCACGGCGAGGGCTGGTTCGCCGACTGCGCGATCATCGGCC
TGGTCCACCCGCTCGACGCCGAGGACGTGCTGGCCCGGATCGCCCGGCTGCGGGCCGGTGAGATCGACTCGATCAGCTAC
CGCGGGCTGTTCCGCGACGCCGAGGGCGGCGACCTGCGGCTCCGGCTCGACGCGGCCCTGCTCCGCGAGCCCGGTGGCCG
GCCGTACGCGATCGCGGCCTCGGTCGGCGACCCCGACGACCTCGACGGCCCCGGCGACCTCGAGGGCGGGGCGGGCGCGG
TCGGTACGGCGGACGGGTCGGCGAGCGACCCCCAGGAGGCCCGCGGGCTTCGCGCCGAGGCCCTGGCCCGGCGGGCCTGG
GACGCCGCGGTGGTCATGGACCGTCGGCTGCAGATCGTCTTCGTCGCCGGGGCGCTGGCGCGGCTGCTGCGCTACCGCCC
CGACGAGCTGCTGCACCGCCGCGGCTCGGACTACGTCCACCCCGCCGACGCCCCCACCGTGTCCGGGATGCTGGGCCGGC
TGCTGGCCGAGCCGCGCAGCGCCGAGCACGCGGTGCTGCGGGTCCACGACGGCGAGCAGCGGTGGCGCTGGGTGGAGGTG
ACCGCCACCAACTGTCTCGACGACCCCGAGATCGGGGGCATCGTCGCCAACGTCCGCGACGTCACCGAACGGGTCCGCAC
CGAGGAGGCGCTGAAGCTCTCCGAGGCGCTGCACCGGGCGATGGTCGAGACCGCCCAGGAAGGCATCATGGCCACCTCGC
CCGAAGGCAAGGTGATGTTCGCCAACGAGACCGCCGCGGTGATCGTCGGCCGCCCGGTCGACGAGATGTACGGCGCGGAC
CCGCGGCGGCTGTTCGGGCTGCCGGACGCGGACTCCGACGACGAGGTCGCCACCCACGAGGTCGTCCACCTGCGCCCCGA
CGGCAGCGAGCGGATCCTGGAGATCTCGCTGCGTCCGCTCAACAGCCGCGACGGCCGGCTCGGCTCGTTGGTCTCGATCT
ACGACGTCACCGACGCCCGGCACGCGGAGCGGGCGCTGCGCCGTCGAGCCCTGCACGACTCGCTGACCTCGCTGCCGAAC
CGCTACCTGTTCCTCGACCGGCTCGAGACCGCGGCCGCCCGGCAGCGCCGCTTCGAGGGCCGGGGGACCGCCGTGCTGTT
CCTCGACCTCGATGGGTTCAAGCAGGTCAACGACGGCTTCGGCCACGAGGCCGGGGACGCGGTCCTGCGGGAGGTGGCGG
CGCGGCTGCTGGCCTCGGTGCGCGGGACGGACACGGTCGGCCGCCTGGGCGGCGACGAGTTCGCGGTGATCTGCGAGGAC
ACCGGCAGCGAGGAGGCGCTCGTGGTCGCCCAGCGCATCCTCGACGCCCTGCACGACCCGATCCGGGTCGGCGACCACGA
CCACCCGATCGGGCTGAGCATCGGGGTGGCGCTGGCACCGCCGTACGACTTCGACGAGCTGGTCCGCCGGGCCGACGAGG
CGATGTACCGGGCCAAGCACGTCGGCGGCAGCCGGATCGCGGTGGCCGGTCAGGACGACGGCGAGGGGCCGGTGCCCACG
GAGTAG

Upstream 100 bases:

>100_bases
GAGCGCTGGGGGAGCGCGGAGGGCATGACCGGTCCGGGGGGCGGTGCGGTCTACCGCAGAAGTCGGAATTTGTTCTAGGG
CGGAAGGACCGGCGACTAGC

Downstream 100 bases:

>100_bases
GCCCGGCACAGCGCGCCGGTCCGAGTCGCCTCCTCGGGGGACACGGCGGGGCTCCACAGCCAGCCCTGTCCCGCGTCGGC
GCCGAGGCGGCGCAGCACGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MTGKGAALGEPLVPLASRTDGLLASPPPSGGMMREIDQGQLLASIAATSHDCILSLDSDARIRWASPATEQVLGWRPDDL
AGCELGVLFPRDGSELRDATVARLLTGEQVEPFIDAGVRRDGSSFKAQVTLGPVHGPGDEITGVILILRDVTAQLHEQRE
LALALEMSRAHFDQATTAQAILDLSGRLESVNPAWCDLFGHGEGWFADCAIIGLVHPLDAEDVLARIARLRAGEIDSISY
RGLFRDAEGGDLRLRLDAALLREPGGRPYAIAASVGDPDDLDGPGDLEGGAGAVGTADGSASDPQEARGLRAEALARRAW
DAAVVMDRRLQIVFVAGALARLLRYRPDELLHRRGSDYVHPADAPTVSGMLGRLLAEPRSAEHAVLRVHDGEQRWRWVEV
TATNCLDDPEIGGIVANVRDVTERVRTEEALKLSEALHRAMVETAQEGIMATSPEGKVMFANETAAVIVGRPVDEMYGAD
PRRLFGLPDADSDDEVATHEVVHLRPDGSERILEISLRPLNSRDGRLGSLVSIYDVTDARHAERALRRRALHDSLTSLPN
RYLFLDRLETAAARQRRFEGRGTAVLFLDLDGFKQVNDGFGHEAGDAVLREVAARLLASVRGTDTVGRLGGDEFAVICED
TGSEEALVVAQRILDALHDPIRVGDHDHPIGLSIGVALAPPYDFDELVRRADEAMYRAKHVGGSRIAVAGQDDGEGPVPT
E

Sequences:

>Translated_721_residues
MTGKGAALGEPLVPLASRTDGLLASPPPSGGMMREIDQGQLLASIAATSHDCILSLDSDARIRWASPATEQVLGWRPDDL
AGCELGVLFPRDGSELRDATVARLLTGEQVEPFIDAGVRRDGSSFKAQVTLGPVHGPGDEITGVILILRDVTAQLHEQRE
LALALEMSRAHFDQATTAQAILDLSGRLESVNPAWCDLFGHGEGWFADCAIIGLVHPLDAEDVLARIARLRAGEIDSISY
RGLFRDAEGGDLRLRLDAALLREPGGRPYAIAASVGDPDDLDGPGDLEGGAGAVGTADGSASDPQEARGLRAEALARRAW
DAAVVMDRRLQIVFVAGALARLLRYRPDELLHRRGSDYVHPADAPTVSGMLGRLLAEPRSAEHAVLRVHDGEQRWRWVEV
TATNCLDDPEIGGIVANVRDVTERVRTEEALKLSEALHRAMVETAQEGIMATSPEGKVMFANETAAVIVGRPVDEMYGAD
PRRLFGLPDADSDDEVATHEVVHLRPDGSERILEISLRPLNSRDGRLGSLVSIYDVTDARHAERALRRRALHDSLTSLPN
RYLFLDRLETAAARQRRFEGRGTAVLFLDLDGFKQVNDGFGHEAGDAVLREVAARLLASVRGTDTVGRLGGDEFAVICED
TGSEEALVVAQRILDALHDPIRVGDHDHPIGLSIGVALAPPYDFDELVRRADEAMYRAKHVGGSRIAVAGQDDGEGPVPT
E
>Mature_720_residues
TGKGAALGEPLVPLASRTDGLLASPPPSGGMMREIDQGQLLASIAATSHDCILSLDSDARIRWASPATEQVLGWRPDDLA
GCELGVLFPRDGSELRDATVARLLTGEQVEPFIDAGVRRDGSSFKAQVTLGPVHGPGDEITGVILILRDVTAQLHEQREL
ALALEMSRAHFDQATTAQAILDLSGRLESVNPAWCDLFGHGEGWFADCAIIGLVHPLDAEDVLARIARLRAGEIDSISYR
GLFRDAEGGDLRLRLDAALLREPGGRPYAIAASVGDPDDLDGPGDLEGGAGAVGTADGSASDPQEARGLRAEALARRAWD
AAVVMDRRLQIVFVAGALARLLRYRPDELLHRRGSDYVHPADAPTVSGMLGRLLAEPRSAEHAVLRVHDGEQRWRWVEVT
ATNCLDDPEIGGIVANVRDVTERVRTEEALKLSEALHRAMVETAQEGIMATSPEGKVMFANETAAVIVGRPVDEMYGADP
RRLFGLPDADSDDEVATHEVVHLRPDGSERILEISLRPLNSRDGRLGSLVSIYDVTDARHAERALRRRALHDSLTSLPNR
YLFLDRLETAAARQRRFEGRGTAVLFLDLDGFKQVNDGFGHEAGDAVLREVAARLLASVRGTDTVGRLGGDEFAVICEDT
GSEEALVVAQRILDALHDPIRVGDHDHPIGLSIGVALAPPYDFDELVRRADEAMYRAKHVGGSRIAVAGQDDGEGPVPTE

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=311, Percent_Identity=33.1189710610932, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787541, Length=176, Percent_Identity=37.5, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI145693134, Length=198, Percent_Identity=33.8383838383838, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786584, Length=186, Percent_Identity=32.258064516129, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI87081881, Length=212, Percent_Identity=33.0188679245283, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=35.7142857142857, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI87082007, Length=176, Percent_Identity=33.5227272727273, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=39.5061728395062, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1787262, Length=178, Percent_Identity=32.5842696629214, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=37.037037037037, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=29.608938547486, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081974, Length=164, Percent_Identity=31.7073170731707, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=26.5060240963855, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77680; Mature: 77549

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00018 EF_HAND_1 ; PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGKGAALGEPLVPLASRTDGLLASPPPSGGMMREIDQGQLLASIAATSHDCILSLDSDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCEEEEECCCC
RIRWASPATEQVLGWRPDDLAGCELGVLFPRDGSELRDATVARLLTGEQVEPFIDAGVRR
EEEECCCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHCCCC
DGSSFKAQVTLGPVHGPGDEITGVILILRDVTAQLHEQRELALALEMSRAHFDQATTAQA
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILDLSGRLESVNPAWCDLFGHGEGWFADCAIIGLVHPLDAEDVLARIARLRAGEIDSISY
HHHHHCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEE
RGLFRDAEGGDLRLRLDAALLREPGGRPYAIAASVGDPDDLDGPGDLEGGAGAVGTADGS
CEEEECCCCCEEEEEEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
ASDPQEARGLRAEALARRAWDAAVVMDRRLQIVFVAGALARLLRYRPDELLHRRGSDYVH
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHCCCCCCC
PADAPTVSGMLGRLLAEPRSAEHAVLRVHDGEQRWRWVEVTATNCLDDPEIGGIVANVRD
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEHHHHH
VTERVRTEEALKLSEALHRAMVETAQEGIMATSPEGKVMFANETAAVIVGRPVDEMYGAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCEEEEEECCHHHHHCCC
PRRLFGLPDADSDDEVATHEVVHLRPDGSERILEISLRPLNSRDGRLGSLVSIYDVTDAR
HHHEECCCCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCHH
HAERALRRRALHDSLTSLPNRYLFLDRLETAAARQRRFEGRGTAVLFLDLDGFKQVNDGF
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHCCC
GHEAGDAVLREVAARLLASVRGTDTVGRLGGDEFAVICEDTGSEEALVVAQRILDALHDP
CCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
IRVGDHDHPIGLSIGVALAPPYDFDELVRRADEAMYRAKHVGGSRIAVAGQDDGEGPVPT
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
E
C
>Mature Secondary Structure 
TGKGAALGEPLVPLASRTDGLLASPPPSGGMMREIDQGQLLASIAATSHDCILSLDSDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHCCCCCEEEEECCCC
RIRWASPATEQVLGWRPDDLAGCELGVLFPRDGSELRDATVARLLTGEQVEPFIDAGVRR
EEEECCCCHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHCCCC
DGSSFKAQVTLGPVHGPGDEITGVILILRDVTAQLHEQRELALALEMSRAHFDQATTAQA
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILDLSGRLESVNPAWCDLFGHGEGWFADCAIIGLVHPLDAEDVLARIARLRAGEIDSISY
HHHHHCCCCCCCCHHEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEE
RGLFRDAEGGDLRLRLDAALLREPGGRPYAIAASVGDPDDLDGPGDLEGGAGAVGTADGS
CEEEECCCCCEEEEEEEHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
ASDPQEARGLRAEALARRAWDAAVVMDRRLQIVFVAGALARLLRYRPDELLHRRGSDYVH
CCCHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCHHHHHHCCCCCCC
PADAPTVSGMLGRLLAEPRSAEHAVLRVHDGEQRWRWVEVTATNCLDDPEIGGIVANVRD
CCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEHHHHH
VTERVRTEEALKLSEALHRAMVETAQEGIMATSPEGKVMFANETAAVIVGRPVDEMYGAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCCEEEEEECCHHHHHCCC
PRRLFGLPDADSDDEVATHEVVHLRPDGSERILEISLRPLNSRDGRLGSLVSIYDVTDAR
HHHEECCCCCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEECCCHH
HAERALRRRALHDSLTSLPNRYLFLDRLETAAARQRRFEGRGTAVLFLDLDGFKQVNDGF
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHCCC
GHEAGDAVLREVAARLLASVRGTDTVGRLGGDEFAVICEDTGSEEALVVAQRILDALHDP
CCCHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
IRVGDHDHPIGLSIGVALAPPYDFDELVRRADEAMYRAKHVGGSRIAVAGQDDGEGPVPT
CCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]