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The map label for this gene is pilD [H]

Identifier: 119715374

GI number: 119715374

Start: 1203269

End: 1204054

Strand: Direct

Name: pilD [H]

Synonym: Noca_1136

Alternate gene names: 119715374

Gene position: 1203269-1204054 (Clockwise)

Preceding gene: 119715373

Following gene: 119715375

Centisome position: 24.13

GC content: 77.35

Gene sequence:

>786_bases
GTGACCCTGGCGTCGAGCCTCGGGTTCGGGCTGCTCGGCCTGCTGATCGGCTCGTTCCTCAACGTGGTCATCCACCGGGT
CCCGGCCGGGCTGTCCCTGGTCTCGCCGGGCTCGGCCTGCCCGGCCTGCGCGCACCCGGTGCGGGCCCGCGACAACGTGC
CGGTGCTCTCGTGGCTGCTGCTGCACGGCCGCTGCCGCGACTGCGCGGCCCCGATCGCCGCCCGCTACCCGCTCGTGGAG
CTCGCCACCGCGGCCCTGTTCGCGAGCGTCGGCTGGCGGTTCGGCGCCACGCCGTACACCGCCGCCGCGCTGGTCGTGGC
CGCCGCCGGCGTCGCCCTGTTCATGATCGACCTGGACCACCGCCGGCTGCCCTTCGAGATCACCGGCGCGATGGCGCTCG
GCACGACGATCGCGCTGGCCATCGACGCGGCCCGGCACGGCACCGCCCCGGTCGTCCCCGCGCTGCTGGCCGCCGCGCTC
TGGCTCGCCGTGTACGGCGGGATCTGGCTGGTCACGGCCGGCCGGGGGATGGGCCTGGGCGACGTCGCCCTGGCGCCGGT
CCTCGGCCTGGCACTCGGCTGGCTCGGCTGGGGAGCCGCGCTCGTGGGCCTGGGCGCCGGCTTCGTGATCGGCGCGGCGG
TCGGGGTGGGGCTGCTCGCCGCCGGGCGCGCCCGGGCCGGCGCCAGGATCCCGCACGGACCCTTCTTGCTCAGCGGCGCC
GCACTCGGCATGCTCGCGGGTGGCCCGCTCGCCGCGTCGTACCTCACGCTCGTCGGCCTGGGCTAG

Upstream 100 bases:

>100_bases
CGGACCGCGGCGGGGACCGCGGCCGGCTGATCTCCGTGCTCGGCGCCGCCGAGCGGGACGCGCTGGCGCGCACGCTGGAG
CCGGAGCCGGAGCCGGCGTC

Downstream 100 bases:

>100_bases
GACGCGCGAGCGCGCACCGGCACGAACCCGTATGAACTCCTGAGAGCCAGTACGAACCGGTGGCCCGGGTGACTCAAGTG
GCGGCCCGTCCGCACCGATG

Product: peptidase A24A domain-containing protein

Products: NA

Alternate protein names: Leader peptidase; Prepilin peptidase; N-methyltransferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTLASSLGFGLLGLLIGSFLNVVIHRVPAGLSLVSPGSACPACAHPVRARDNVPVLSWLLLHGRCRDCAAPIAARYPLVE
LATAALFASVGWRFGATPYTAAALVVAAAGVALFMIDLDHRRLPFEITGAMALGTTIALAIDAARHGTAPVVPALLAAAL
WLAVYGGIWLVTAGRGMGLGDVALAPVLGLALGWLGWGAALVGLGAGFVIGAAVGVGLLAAGRARAGARIPHGPFLLSGA
ALGMLAGGPLAASYLTLVGLG

Sequences:

>Translated_261_residues
MTLASSLGFGLLGLLIGSFLNVVIHRVPAGLSLVSPGSACPACAHPVRARDNVPVLSWLLLHGRCRDCAAPIAARYPLVE
LATAALFASVGWRFGATPYTAAALVVAAAGVALFMIDLDHRRLPFEITGAMALGTTIALAIDAARHGTAPVVPALLAAAL
WLAVYGGIWLVTAGRGMGLGDVALAPVLGLALGWLGWGAALVGLGAGFVIGAAVGVGLLAAGRARAGARIPHGPFLLSGA
ALGMLAGGPLAASYLTLVGLG
>Mature_260_residues
TLASSLGFGLLGLLIGSFLNVVIHRVPAGLSLVSPGSACPACAHPVRARDNVPVLSWLLLHGRCRDCAAPIAARYPLVEL
ATAALFASVGWRFGATPYTAAALVVAAAGVALFMIDLDHRRLPFEITGAMALGTTIALAIDAARHGTAPVVPALLAAALW
LAVYGGIWLVTAGRGMGLGDVALAPVLGLALGWLGWGAALVGLGAGFVIGAAVGVGLLAAGRARAGARIPHGPFLLSGAA
LGMLAGGPLAASYLTLVGLG

Specific function: Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue [H]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family [H]

Homologues:

Organism=Escherichia coli, GI87082194, Length=246, Percent_Identity=34.9593495934959, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010627
- InterPro:   IPR014032
- InterPro:   IPR000045 [H]

Pfam domain/function: PF06750 DiS_P_DiS; PF01478 Peptidase_A24 [H]

EC number: =3.4.23.43 [H]

Molecular weight: Translated: 25998; Mature: 25867

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASSLGFGLLGLLIGSFLNVVIHRVPAGLSLVSPGSACPACAHPVRARDNVPVLSWLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCCCCCCCCCHHHHHHH
LHGRCRDCAAPIAARYPLVELATAALFASVGWRFGATPYTAAALVVAAAGVALFMIDLDH
HHCCCHHHHCHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCC
RRLPFEITGAMALGTTIALAIDAARHGTAPVVPALLAAALWLAVYGGIWLVTAGRGMGLG
CCCCEEEHHHHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCH
DVALAPVLGLALGWLGWGAALVGLGAGFVIGAAVGVGLLAAGRARAGARIPHGPFLLSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALGMLAGGPLAASYLTLVGLG
HHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TLASSLGFGLLGLLIGSFLNVVIHRVPAGLSLVSPGSACPACAHPVRARDNVPVLSWLL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHCCCCCCCCCCHHHHHHH
LHGRCRDCAAPIAARYPLVELATAALFASVGWRFGATPYTAAALVVAAAGVALFMIDLDH
HHCCCHHHHCHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCC
RRLPFEITGAMALGTTIALAIDAARHGTAPVVPALLAAALWLAVYGGIWLVTAGRGMGLG
CCCCEEEHHHHHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCH
DVALAPVLGLALGWLGWGAALVGLGAGFVIGAAVGVGLLAAGRARAGARIPHGPFLLSGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
ALGMLAGGPLAASYLTLVGLG
HHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA