Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 119715176

GI number: 119715176

Start: 978478

End: 979404

Strand: Direct

Name: aroB [H]

Synonym: Noca_0931

Alternate gene names: 119715176

Gene position: 978478-979404 (Clockwise)

Preceding gene: 119715175

Following gene: 119715177

Centisome position: 19.63

GC content: 74.54

Gene sequence:

>927_bases
GTGCGTGTAGCGCCCGTCGCAGCCATCGACTGCGGCACCAACACGATCAAGCTCCTGGTGGGCACCGTGCCCGAGGCGGG
GGGCCTCGAGGTCGACGTGCGGGAGATGCGGATCGTGCGGCTCGGCCAGGACCTCGACCGCACCGGCCGGATCGCCGAGG
AGGCACTGGAGCGGACGTTCGCCGCCATCGACGAGTACGCCGCGGTGATCCGCGGCCACGACGTGCCGCCCGAGCGGATC
CGCTTCGTCGCGACCTCGGCCACCCGCGACGCGGCGAACGCCGTGGACTTCGTCGCCGGCGTCCGCGAGCGGCTGGGCGT
CGAGCCCGACGTGGTCACCGGAGCCGCGGAGGCCGCCCTGGCCTTCGACGGAGCGGTCCGCAACCTGCGCACCGCGCCGG
CCGCGCCGGTGCTGGTCGTCGACATCGGCGGCGGGTCCACCGAGCTGATCCTGGGCAGCACCGAGCCGGCAAGCGCCCAC
TCGATGGACATCGGCTCGGTGCGGCTGCATGAGCGACACCTGGCCGGCGACCCTCCGACGCCCCAGCAGGTGGCGGCCTG
CCTCGCCGACATCGACGCCCACCTCGACGCCAGCCCCGTGGACCTCGCTGCCGCCGCGACCGTCGTCGGCGTGGCCGGGA
CGATCACCACGGTGGGCGCCGCGGTGCTGGACCTCCCGGCGTACGACCGCGACGCCCTCGACCAGGCGGTCCTCGACGTC
GCCGACGTGCACGCCGCGGTCGACCGGCTGGTCGCGATGAGCCACCAGGAGCGCCGCGCCCTGGGCTTCATGCACCCCGG
CCGCGCGGACGTCATCGACGCCGGTGCGTTGATCCTCTCCGCGGTCCTGCGCCGCACCCGCGTGGCCGACCTCGTGGTGT
CCGAGGCCGACATCCTCGACGGGATCGCTTGGTCGATCGGCCGGTGA

Upstream 100 bases:

>100_bases
TGCACGTGCTCGCCGGCCAGGCTCTCGCCCAGGGCCGCGGCGTCAACCCGCTGGGCGACGAGGTCCTCGACCTCCTCGGC
CCCTGGTGGGGGTCCGGCCC

Downstream 100 bases:

>100_bases
GACCGGCGGCTGACGTACGGGCGTTTCTGGACCGGGCCTGGTGGGCACCGGGGCCCCATGACCGATCCGCGTACGACGAC
CGATGAACCAGTCGGCGCAC

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRVAPVAAIDCGTNTIKLLVGTVPEAGGLEVDVREMRIVRLGQDLDRTGRIAEEALERTFAAIDEYAAVIRGHDVPPERI
RFVATSATRDAANAVDFVAGVRERLGVEPDVVTGAAEAALAFDGAVRNLRTAPAAPVLVVDIGGGSTELILGSTEPASAH
SMDIGSVRLHERHLAGDPPTPQQVAACLADIDAHLDASPVDLAAAATVVGVAGTITTVGAAVLDLPAYDRDALDQAVLDV
ADVHAAVDRLVAMSHQERRALGFMHPGRADVIDAGALILSAVLRRTRVADLVVSEADILDGIAWSIGR

Sequences:

>Translated_308_residues
MRVAPVAAIDCGTNTIKLLVGTVPEAGGLEVDVREMRIVRLGQDLDRTGRIAEEALERTFAAIDEYAAVIRGHDVPPERI
RFVATSATRDAANAVDFVAGVRERLGVEPDVVTGAAEAALAFDGAVRNLRTAPAAPVLVVDIGGGSTELILGSTEPASAH
SMDIGSVRLHERHLAGDPPTPQQVAACLADIDAHLDASPVDLAAAATVVGVAGTITTVGAAVLDLPAYDRDALDQAVLDV
ADVHAAVDRLVAMSHQERRALGFMHPGRADVIDAGALILSAVLRRTRVADLVVSEADILDGIAWSIGR
>Mature_308_residues
MRVAPVAAIDCGTNTIKLLVGTVPEAGGLEVDVREMRIVRLGQDLDRTGRIAEEALERTFAAIDEYAAVIRGHDVPPERI
RFVATSATRDAANAVDFVAGVRERLGVEPDVVTGAAEAALAFDGAVRNLRTAPAAPVLVVDIGGGSTELILGSTEPASAH
SMDIGSVRLHERHLAGDPPTPQQVAACLADIDAHLDASPVDLAAAATVVGVAGTITTVGAAVLDLPAYDRDALDQAVLDV
ADVHAAVDRLVAMSHQERRALGFMHPGRADVIDAGALILSAVLRRTRVADLVVSEADILDGIAWSIGR

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=171, Percent_Identity=40.3508771929825, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788848, Length=177, Percent_Identity=29.9435028248588, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 32033; Mature: 32033

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAPVAAIDCGTNTIKLLVGTVPEAGGLEVDVREMRIVRLGQDLDRTGRIAEEALERTF
CCCCCEEEEECCCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAIDEYAAVIRGHDVPPERIRFVATSATRDAANAVDFVAGVRERLGVEPDVVTGAAEAAL
HHHHHHHHHHHCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AFDGAVRNLRTAPAAPVLVVDIGGGSTELILGSTEPASAHSMDIGSVRLHERHLAGDPPT
HHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEHHHCCCCCCC
PQQVAACLADIDAHLDASPVDLAAAATVVGVAGTITTVGAAVLDLPAYDRDALDQAVLDV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ADVHAAVDRLVAMSHQERRALGFMHPGRADVIDAGALILSAVLRRTRVADLVVSEADILD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAWSIGR
HHHHHCCC
>Mature Secondary Structure
MRVAPVAAIDCGTNTIKLLVGTVPEAGGLEVDVREMRIVRLGQDLDRTGRIAEEALERTF
CCCCCEEEEECCCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AAIDEYAAVIRGHDVPPERIRFVATSATRDAANAVDFVAGVRERLGVEPDVVTGAAEAAL
HHHHHHHHHHHCCCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AFDGAVRNLRTAPAAPVLVVDIGGGSTELILGSTEPASAHSMDIGSVRLHERHLAGDPPT
HHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEHHHCCCCCCC
PQQVAACLADIDAHLDASPVDLAAAATVVGVAGTITTVGAAVLDLPAYDRDALDQAVLDV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ADVHAAVDRLVAMSHQERRALGFMHPGRADVIDAGALILSAVLRRTRVADLVVSEADILD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAWSIGR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]