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The map label for this gene is etfA [H]

Identifier: 119714887

GI number: 119714887

Start: 676625

End: 677590

Strand: Reverse

Name: etfA [H]

Synonym: Noca_0639

Alternate gene names: 119714887

Gene position: 677590-676625 (Counterclockwise)

Preceding gene: 119714888

Following gene: 119714886

Centisome position: 13.59

GC content: 69.77

Gene sequence:

>966_bases
ATGTCTGAAGTTCTCGTTCTCATCGACCACGTCGACGGCGCGGTGCGCAAGCCGACGTACGAGCTCCTGACCATCGCCAA
GCGGCTCGGCGAGCCGTCGGCGGTCTTCATCGGCAGCTCGGCCCAGGGCGCCGACGTGGCCGAGAAGGTGAAGAAGTACG
GCGCCGAGAAGGTCTACGTCGTCGACGACGCGCAGCTCAAGGGCTACCTGGTGGCGCCCAAGGCCGAGGCCCTCCAGCAG
CTGGCGGAGAAGGCTCAGGCCGGTGGGGGCGTCGCGGCGATCCTGATCCCCTCCACCATGGAGGGCAAGGAGATCGCCGG
TCGCCTCGCGATCAAGCTCGAGTCCGGCCTGATCACCGACGCGGTCGACGTGGAGGCCGACGGCACCACCACCCAGTCGG
TCTTCGCGGGCAACTACACCGCCAAGGCCAAGGTCACCCAGGGCACCCCGATCATCACGGTCAAGCCGAACTCCGCCGCG
CCGGAGGAGGCCGCCGGTGCCGGGACCGTCGAGGAGTTCGCCGCGACCGTGTCCGACGACGCGAAGGCCGCACAGATCGT
GGCCTCCCAGCCGCGGAAGGCGACCGGGCGTCCCGAGCTGACCGAGGCCGCGATCGTGGTCGCCGGCGGTCGTGGCACCG
GTGGCAGCTTCGAGGCCGTCGAAGGCCTCGCGGATGCGCTGGGTGGTGCCGTCGGCGCCTCGCGGGCCGCGGTCGACTCC
GGCTGGATCCCGCACACCTTCCAGATCGGCCAGACCGGCAAGACCGTCTCGCCGCAGCTCTACATCGCCACCGGCATCTC
CGGCGCGATCCAGCACCGCGCCGGTATGCAGACCTCGAAGACGATCGTCGCGGTCAACAAGGACGAGGAGGCCCCGATCT
TCGAGCTCGTCGACTTCGGCGTGGTGGGCGACCTGCACACGGTCCTCCCCGCGCTGACCGACGAAGTCACCAAGCGCAAG
GGCTGA

Upstream 100 bases:

>100_bases
CGCGCACCGCCGGCGAGATCGTCAAGGACGAGGACGGCTCGGGCGCCACGGCGCTGGCCGGGTTCCTCGCCTCGAAGAAG
TTCATCTGAGGAGCTGACCG

Downstream 100 bases:

>100_bases
GTGCGACATGGTCCGTCTGCTAGGCGTCGTCAACGTGACGCCCGACTCCTTCTCCGATGGCGGTCTCTACCCCAGCGTTG
ACGCAGCTGTAGGCGCGGGA

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSSAQGADVAEKVKKYGAEKVYVVDDAQLKGYLVAPKAEALQQ
LAEKAQAGGGVAAILIPSTMEGKEIAGRLAIKLESGLITDAVDVEADGTTTQSVFAGNYTAKAKVTQGTPIITVKPNSAA
PEEAAGAGTVEEFAATVSDDAKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFEAVEGLADALGGAVGASRAAVDS
GWIPHTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGDLHTVLPALTDEVTKRK
G

Sequences:

>Translated_321_residues
MSEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSSAQGADVAEKVKKYGAEKVYVVDDAQLKGYLVAPKAEALQQ
LAEKAQAGGGVAAILIPSTMEGKEIAGRLAIKLESGLITDAVDVEADGTTTQSVFAGNYTAKAKVTQGTPIITVKPNSAA
PEEAAGAGTVEEFAATVSDDAKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFEAVEGLADALGGAVGASRAAVDS
GWIPHTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGDLHTVLPALTDEVTKRK
G
>Mature_320_residues
SEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSSAQGADVAEKVKKYGAEKVYVVDDAQLKGYLVAPKAEALQQL
AEKAQAGGGVAAILIPSTMEGKEIAGRLAIKLESGLITDAVDVEADGTTTQSVFAGNYTAKAKVTQGTPIITVKPNSAAP
EEAAGAGTVEEFAATVSDDAKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFEAVEGLADALGGAVGASRAAVDSG
WIPHTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFGVVGDLHTVLPALTDEVTKRKG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=320, Percent_Identity=39.375, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI189181759, Length=269, Percent_Identity=41.2639405204461, Blast_Score=181, Evalue=5e-46,
Organism=Escherichia coli, GI1787990, Length=291, Percent_Identity=31.6151202749141, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786226, Length=327, Percent_Identity=31.1926605504587, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI87082157, Length=224, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17506929, Length=316, Percent_Identity=39.5569620253165, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6325261, Length=319, Percent_Identity=34.1692789968652, Blast_Score=157, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=40.3846153846154, Blast_Score=207, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=40.3846153846154, Blast_Score=207, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32861; Mature: 32729

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSSAQGADVAEKVKKYGAEKVYV
CCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCEEEE
VDDAQLKGYLVAPKAEALQQLAEKAQAGGGVAAILIPSTMEGKEIAGRLAIKLESGLITD
EECCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCEEEEEEECCCEEC
AVDVEADGTTTQSVFAGNYTAKAKVTQGTPIITVKPNSAAPEEAAGAGTVEEFAATVSDD
EEEECCCCCCCCEEEECCCEEEEEEECCCEEEEECCCCCCCHHHCCCCCHHHHHHHHCCC
AKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFEAVEGLADALGGAVGASRAAVDS
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCC
GWIPHTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFG
CCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHC
VVGDLHTVLPALTDEVTKRKG
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEVLVLIDHVDGAVRKPTYELLTIAKRLGEPSAVFIGSSAQGADVAEKVKKYGAEKVYV
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCCEEEE
VDDAQLKGYLVAPKAEALQQLAEKAQAGGGVAAILIPSTMEGKEIAGRLAIKLESGLITD
EECCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCEEEEEEECCCEEC
AVDVEADGTTTQSVFAGNYTAKAKVTQGTPIITVKPNSAAPEEAAGAGTVEEFAATVSDD
EEEECCCCCCCCEEEECCCEEEEEEECCCEEEEECCCCCCCHHHCCCCCHHHHHHHHCCC
AKAAQIVASQPRKATGRPELTEAAIVVAGGRGTGGSFEAVEGLADALGGAVGASRAAVDS
HHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCC
GWIPHTFQIGQTGKTVSPQLYIATGISGAIQHRAGMQTSKTIVAVNKDEEAPIFELVDFG
CCCCCEEEECCCCCCCCCEEEEEECCCHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHC
VVGDLHTVLPALTDEVTKRKG
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]