Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 119386275

GI number: 119386275

Start: 716125

End: 716892

Strand: Direct

Name: ompR [H]

Synonym: Pden_3566

Alternate gene names: 119386275

Gene position: 716125-716892 (Clockwise)

Preceding gene: 119386274

Following gene: 119386278

Centisome position: 41.39

GC content: 68.75

Gene sequence:

>768_bases
ATGGAACGCCCCGCCATGATTTCCCAGCCGGCCGGCACTCCGGCCCTGACGCATGAGACGGAACCCCCTCAGCGCATCCT
TTTCGTCGAGGATGACCGCAAGCTCAGCGCTTTTCTCTGCCGCTACTTCACCGAACAGGGCTATCTGGTCGAGGCCGCGC
ATGACGGCGCCGCGATGCGCCGGGCGCTGGCCGCCAAGGGGTTCGACCTCGTGGTGCTGGACGTGGGCCTGCCGGGCCGA
GAGGACGGCTATGTGCTGGCGCGCGAACTGAAGAAAGAGCGCGACATCGGCATCCTGTTCCTCTCGGCCCGGCAAGATGC
GCTGGACCGCATCGTCGGGCTCGAGATCGGCGCCGACGATTTCCTGGTCAAGCCCTTCGAGCCGCGCGAGCTTCTGGCCC
GTATCCGCGCCATCCTGCGCCGCCTGCCCGCCGGCACGGCCCGGCCGCGGGGCGAAGGGCGCCGGATCGGCTTCGACGGC
TGGTTGCTGGATCTCGATGCCCGCGTGTTGCGGGATGCGCAGGGCGGGGTGCAGAACCTGACCACGCAGGAGTTCAACCT
GCTCAGCGTGCTGGCGCAGCGGCCCGGACGGGTGCTGAGCCGGGACCAACTTCTGGACCTTACCGTCAGCCGCCACTGGT
CGCCCTACGACCGCTCGGTCGATGTGATGATCGGCAAGATCCGCCGCAAGATCGGCGACAACGGGCCGGAGCCGCGCCGC
ATCCGCACCATCCGCGGCACCGGCTACATGTTCTCGCCCGAGCCCTGA

Upstream 100 bases:

>100_bases
GCCCCGGAGCTTGCGAGGGGGCTATGAAGGCCGATTTCGCTCGGCTATGTTGAGAAAGCTCCAGGTTTCCCGACGCCTGA
ACCGGCCGCATCCAAGCCTG

Downstream 100 bases:

>100_bases
TCCGGCCCGGTGCACGGCTTCAGGCAGGGCAGGTCCAGCACCGCGCGCGCGCCGCCGCCCTCGGCATTGCCGATGCGAAA
GTCGCCGCCGCTGACCAGCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MERPAMISQPAGTPALTHETEPPQRILFVEDDRKLSAFLCRYFTEQGYLVEAAHDGAAMRRALAAKGFDLVVLDVGLPGR
EDGYVLARELKKERDIGILFLSARQDALDRIVGLEIGADDFLVKPFEPRELLARIRAILRRLPAGTARPRGEGRRIGFDG
WLLDLDARVLRDAQGGVQNLTTQEFNLLSVLAQRPGRVLSRDQLLDLTVSRHWSPYDRSVDVMIGKIRRKIGDNGPEPRR
IRTIRGTGYMFSPEP

Sequences:

>Translated_255_residues
MERPAMISQPAGTPALTHETEPPQRILFVEDDRKLSAFLCRYFTEQGYLVEAAHDGAAMRRALAAKGFDLVVLDVGLPGR
EDGYVLARELKKERDIGILFLSARQDALDRIVGLEIGADDFLVKPFEPRELLARIRAILRRLPAGTARPRGEGRRIGFDG
WLLDLDARVLRDAQGGVQNLTTQEFNLLSVLAQRPGRVLSRDQLLDLTVSRHWSPYDRSVDVMIGKIRRKIGDNGPEPRR
IRTIRGTGYMFSPEP
>Mature_255_residues
MERPAMISQPAGTPALTHETEPPQRILFVEDDRKLSAFLCRYFTEQGYLVEAAHDGAAMRRALAAKGFDLVVLDVGLPGR
EDGYVLARELKKERDIGILFLSARQDALDRIVGLEIGADDFLVKPFEPRELLARIRAILRRLPAGTARPRGEGRRIGFDG
WLLDLDARVLRDAQGGVQNLTTQEFNLLSVLAQRPGRVLSRDQLLDLTVSRHWSPYDRSVDVMIGKIRRKIGDNGPEPRR
IRTIRGTGYMFSPEP

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=236, Percent_Identity=43.2203389830509, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=39.1304347826087, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.8974358974359, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=36.4444444444444, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=35.4700854700855, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=35.7758620689655, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=36.2445414847162, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=34.061135371179, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=33.920704845815, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=36.4035087719298, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=30.8333333333333, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.4978165938865, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.0175438596491, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=31.2775330396476, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28680; Mature: 28680

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERPAMISQPAGTPALTHETEPPQRILFVEDDRKLSAFLCRYFTEQGYLVEAAHDGAAMR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHH
RALAAKGFDLVVLDVGLPGREDGYVLARELKKERDIGILFLSARQDALDRIVGLEIGADD
HHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCEEECCCC
FLVKPFEPRELLARIRAILRRLPAGTARPRGEGRRIGFDGWLLDLDARVLRDAQGGVQNL
CEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEHHHHHHHHHCCCHHHC
TTQEFNLLSVLAQRPGRVLSRDQLLDLTVSRHWSPYDRSVDVMIGKIRRKIGDNGPEPRR
CHHHHHHHHHHHHCCCCCCCCHHHHEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
IRTIRGTGYMFSPEP
EEEEECCCEEECCCC
>Mature Secondary Structure
MERPAMISQPAGTPALTHETEPPQRILFVEDDRKLSAFLCRYFTEQGYLVEAAHDGAAMR
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHH
RALAAKGFDLVVLDVGLPGREDGYVLARELKKERDIGILFLSARQDALDRIVGLEIGADD
HHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCHHHHHHHHCEEECCCC
FLVKPFEPRELLARIRAILRRLPAGTARPRGEGRRIGFDGWLLDLDARVLRDAQGGVQNL
CEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEHHHHHHHHHCCCHHHC
TTQEFNLLSVLAQRPGRVLSRDQLLDLTVSRHWSPYDRSVDVMIGKIRRKIGDNGPEPRR
CHHHHHHHHHHHHCCCCCCCCHHHHEEHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
IRTIRGTGYMFSPEP
EEEEECCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]