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The map label for this gene is fmdA [H]

Identifier: 119386278

GI number: 119386278

Start: 720832

End: 722058

Strand: Direct

Name: fmdA [H]

Synonym: Pden_3569

Alternate gene names: 119386278

Gene position: 720832-722058 (Clockwise)

Preceding gene: 119386275

Following gene: 119386279

Centisome position: 41.66

GC content: 65.2

Gene sequence:

>1227_bases
ATGTCGAAAACCGTATTCAAGGTCGATCTCAACACGGCCCCCGAGGACGCCGCGCAAAAGCCGCACAACCGCTGGCATCC
CGACATCCCGATGGTCGAGACCTTCAAGCCCGGCGAGGTGCTGCGCATCGAATGCTACGACTGGACCGGCGGCCAGATCG
GCAACAACGACAGTGCCAACGATATCCGCGACGTCGACCTGACGCGGGTGCATTACCTGTCCGGTCCCTTCGGCTTCGAG
GGGGCCGAGCCGGGCGACCTGCTGGTGGTGGACATCCTCGATATCGGTGCGCTCGAGGATTCGCGCTGGGGCTTCAACGG
GCTTTTCGCCAAGGAGAACGGCGGCGGCTTCCTGACCGAGCATTACCCGCAGGCCACCAAGTCGATCTGGGATTTCGAGG
GCATCTACACCACCTCGCGCCATATCCCCGGCGTGCGCTATCCCGGCCTGATCCATCCCGGCCTGATCGGCTGCCTGCCC
GACCACAAGCTGCTGGCCGAGGCGAACCGGCGCGAGGCGGCGCTGATCGCCACCGACCCGAACCGCGTCCCGCCGCTGGC
GGCGCCGCCCCATGCCGCGACCGCGCTGATGGGGCAGATGAAGGGCGCCGCCGCGCAAAGCGCCGCCGATGAGGCCTGGC
GCACGGTGCCGCCGCGCGAGCATGGCGGCAACTGCGACATCAAGAACCTGTCGCGCGGCTCCAAGGTCTATTTCCCGGTC
TATGTGAAGGGCGGCGGCCTTTCGATGGGCGACATTCATTTCAGCCAGGGCGACGGCGAGATCACCTTTTGCGGCGCCAT
CGAGATGGCCGGCTGGATCGAGATCAAGGTCGAGATCATCAAGGGCGGCATGGCGAAATACGGCGTCATCAACCCGATCT
TCCGGCCTTCGCCCATCGACCCGCATTTCGACGACTACCTGATCTTCGAGGGCATCTCGGTCGACGAGCACACGGGCGAG
CAATATTACCTGGACGCCCATGTCGCCTATCGCCGGGCCTGCCTCAACGCCATCGAATACCTGAAGAAGTTCGGCTATTC
GGGCGAGCAGGCCTATATGATCCTCGGCACCGCCCCGGTCGAGGGCCGCATCGCCGGCATCGTGGACATCCCCAATGTCT
GCGCGACGCTGGCGATCCCGACCGGCATCTTCGACTTCGACATCCGGCCCAACGGCGACGGGCCGAAACGCTCGGTCCCC
GAGGTTTCGGTCGCCAGAACCAGCTGA

Upstream 100 bases:

>100_bases
TTACATTTCCGCGGCTTTCGGCATGCATTGCGATTACATGCCCGGCCCAGGCTGGTCGGGGAACCGGCCTGCCCGCCGGT
CCGCAAGGAGGGAGGAGAAC

Downstream 100 bases:

>100_bases
CGGTTCCACGCGCCCGCGTCCCGGCCTTCGGGGCGCGCGGCTCCACAGGAGGAGAGGTCCATGCTGCTTGGTTTTCTATT
GTTCTATGTGGGCGCGGTGC

Product: formamidase

Products: NA

Alternate protein names: Formamide amidohydrolase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSKTVFKVDLNTAPEDAAQKPHNRWHPDIPMVETFKPGEVLRIECYDWTGGQIGNNDSANDIRDVDLTRVHYLSGPFGFE
GAEPGDLLVVDILDIGALEDSRWGFNGLFAKENGGGFLTEHYPQATKSIWDFEGIYTTSRHIPGVRYPGLIHPGLIGCLP
DHKLLAEANRREAALIATDPNRVPPLAAPPHAATALMGQMKGAAAQSAADEAWRTVPPREHGGNCDIKNLSRGSKVYFPV
YVKGGGLSMGDIHFSQGDGEITFCGAIEMAGWIEIKVEIIKGGMAKYGVINPIFRPSPIDPHFDDYLIFEGISVDEHTGE
QYYLDAHVAYRRACLNAIEYLKKFGYSGEQAYMILGTAPVEGRIAGIVDIPNVCATLAIPTGIFDFDIRPNGDGPKRSVP
EVSVARTS

Sequences:

>Translated_408_residues
MSKTVFKVDLNTAPEDAAQKPHNRWHPDIPMVETFKPGEVLRIECYDWTGGQIGNNDSANDIRDVDLTRVHYLSGPFGFE
GAEPGDLLVVDILDIGALEDSRWGFNGLFAKENGGGFLTEHYPQATKSIWDFEGIYTTSRHIPGVRYPGLIHPGLIGCLP
DHKLLAEANRREAALIATDPNRVPPLAAPPHAATALMGQMKGAAAQSAADEAWRTVPPREHGGNCDIKNLSRGSKVYFPV
YVKGGGLSMGDIHFSQGDGEITFCGAIEMAGWIEIKVEIIKGGMAKYGVINPIFRPSPIDPHFDDYLIFEGISVDEHTGE
QYYLDAHVAYRRACLNAIEYLKKFGYSGEQAYMILGTAPVEGRIAGIVDIPNVCATLAIPTGIFDFDIRPNGDGPKRSVP
EVSVARTS
>Mature_407_residues
SKTVFKVDLNTAPEDAAQKPHNRWHPDIPMVETFKPGEVLRIECYDWTGGQIGNNDSANDIRDVDLTRVHYLSGPFGFEG
AEPGDLLVVDILDIGALEDSRWGFNGLFAKENGGGFLTEHYPQATKSIWDFEGIYTTSRHIPGVRYPGLIHPGLIGCLPD
HKLLAEANRREAALIATDPNRVPPLAAPPHAATALMGQMKGAAAQSAADEAWRTVPPREHGGNCDIKNLSRGSKVYFPVY
VKGGGLSMGDIHFSQGDGEITFCGAIEMAGWIEIKVEIIKGGMAKYGVINPIFRPSPIDPHFDDYLIFEGISVDEHTGEQ
YYLDAHVAYRRACLNAIEYLKKFGYSGEQAYMILGTAPVEGRIAGIVDIPNVCATLAIPTGIFDFDIRPNGDGPKRSVPE
VSVARTS

Specific function: Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. Also acts, more slowly, on acetamide, propanamide and butanamide [H]

COG id: COG2421

COG function: function code C; Predicted acetamidase/formamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetamidase/formamidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004304 [H]

Pfam domain/function: PF03069 FmdA_AmdA [H]

EC number: =3.5.1.49 [H]

Molecular weight: Translated: 44493; Mature: 44362

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTVFKVDLNTAPEDAAQKPHNRWHPDIPMVETFKPGEVLRIECYDWTGGQIGNNDSAN
CCCEEEEEECCCCCCHHHHCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCC
DIRDVDLTRVHYLSGPFGFEGAEPGDLLVVDILDIGALEDSRWGFNGLFAKENGGGFLTE
CCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCC
HYPQATKSIWDFEGIYTTSRHIPGVRYPGLIHPGLIGCLPDHKLLAEANRREAALIATDP
CCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCCCEEEEEECC
NRVPPLAAPPHAATALMGQMKGAAAQSAADEAWRTVPPREHGGNCDIKNLSRGSKVYFPV
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEE
YVKGGGLSMGDIHFSQGDGEITFCGAIEMAGWIEIKVEIIKGGMAKYGVINPIFRPSPID
EEECCCCEECEEEEECCCCCEEEEEEEEECCEEEEEEEEEECCCHHCCCCCCCCCCCCCC
PHFDDYLIFEGISVDEHTGEQYYLDAHVAYRRACLNAIEYLKKFGYSGEQAYMILGTAPV
CCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
EGRIAGIVDIPNVCATLAIPTGIFDFDIRPNGDGPKRSVPEVSVARTS
CCEEEEEEECCHHHHHHEECCCEEEEEECCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
SKTVFKVDLNTAPEDAAQKPHNRWHPDIPMVETFKPGEVLRIECYDWTGGQIGNNDSAN
CCEEEEEECCCCCCHHHHCCCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCC
DIRDVDLTRVHYLSGPFGFEGAEPGDLLVVDILDIGALEDSRWGFNGLFAKENGGGFLTE
CCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCC
HYPQATKSIWDFEGIYTTSRHIPGVRYPGLIHPGLIGCLPDHKLLAEANRREAALIATDP
CCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHCCCCCEEEEEECC
NRVPPLAAPPHAATALMGQMKGAAAQSAADEAWRTVPPREHGGNCDIKNLSRGSKVYFPV
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEE
YVKGGGLSMGDIHFSQGDGEITFCGAIEMAGWIEIKVEIIKGGMAKYGVINPIFRPSPID
EEECCCCEECEEEEECCCCCEEEEEEEEECCEEEEEEEEEECCCHHCCCCCCCCCCCCCC
PHFDDYLIFEGISVDEHTGEQYYLDAHVAYRRACLNAIEYLKKFGYSGEQAYMILGTAPV
CCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
EGRIAGIVDIPNVCATLAIPTGIFDFDIRPNGDGPKRSVPEVSVARTS
CCEEEEEEECCHHHHHHEECCCEEEEEECCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841393 [H]