| Definition | Paracoccus denitrificans PD1222 chromosome 2, complete sequence. |
|---|---|
| Accession | NC_008687 |
| Length | 1,730,097 |
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The map label for this gene is fabG [H]
Identifier: 119386252
GI number: 119386252
Start: 690013
End: 690750
Strand: Direct
Name: fabG [H]
Synonym: Pden_3541
Alternate gene names: 119386252
Gene position: 690013-690750 (Clockwise)
Preceding gene: 119386251
Following gene: 119386253
Centisome position: 39.88
GC content: 68.56
Gene sequence:
>738_bases ATGACCTCTCAACCGCTTACCACCGCAATCGTGACGGGCGCAGGCTCGGGCATAGGCCGGGCTATCGCGCATCGCCTGGC TGACGAGGGCCATGCCGTCGTCGTGGCCGACCGTGCCGCCGAGGGGGCGCAGGAAACCGTGCGCCAGCTTGTCGCCATGG GCCGCAGCGCCCGCGCCGCCGTGCTGGACATCACCGACCCGGCGGCGACGCAGGCGCTGATCGACGGCGCGGAAAACCTG CGCGTGCTGGTCAACAATGCCGGCATCTTCAACACCTGCGCATTCGATGCGCTGACCGCCGACGATTTCCGCGGGATGTA TGAGGTCAACCTGGTCGCCATGTTCACCCTTTGCCAGCAGGCGGCCCGCGTGCTGCCCGAGGGCGGACGGATCGTGAACC TTGCGTCGCGCGCGGCCTTCGGGGCGCGGAACTATGCGCATTACGTCGCCTCCAAGGCGGCGGTCGCCGGCTTGACCAAG GCATTGGCGCTGGAACTGGCCGGGCGGCAGATCACCGTGAATGCGGTGGCTCCGGGCGTGATCGCGACCGACATGCTGCT GGAACGGTCCGAGGGGCTGGAGGGCCTGCGCGTCCAGCAACCCACCGGCAAGCTGGGCACGCCCGAGCATATCGCCCATG CGGTCGCCTTTTTCGCCGATCCGCGTGCGGAATATGTCACCGGGCAAGTGCTGATCGTCGATGGCGGCCGCTCGGTCGGC GGCACCGCGGCATTCTGA
Upstream 100 bases:
>100_bases CGACGAAAACACCTTTGGCGTCGAATGATGCCGGGCCCCCGGGCGCGTTAGCGGGCCGGGGGCGATACTTACCGTCAACT GCCGGACCGACTGGTGAATC
Downstream 100 bases:
>100_bases AACGGGAGAGGGGAAATGCTGGAACCAAGCAATCTGGACGGACGGACGGCCATCGTGACCGGCGCGGGGCAGGGGATCGG CCTTGCGATCGCCGAGGCGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 245; Mature: 244
Protein sequence:
>245_residues MTSQPLTTAIVTGAGSGIGRAIAHRLADEGHAVVVADRAAEGAQETVRQLVAMGRSARAAVLDITDPAATQALIDGAENL RVLVNNAGIFNTCAFDALTADDFRGMYEVNLVAMFTLCQQAARVLPEGGRIVNLASRAAFGARNYAHYVASKAAVAGLTK ALALELAGRQITVNAVAPGVIATDMLLERSEGLEGLRVQQPTGKLGTPEHIAHAVAFFADPRAEYVTGQVLIVDGGRSVG GTAAF
Sequences:
>Translated_245_residues MTSQPLTTAIVTGAGSGIGRAIAHRLADEGHAVVVADRAAEGAQETVRQLVAMGRSARAAVLDITDPAATQALIDGAENL RVLVNNAGIFNTCAFDALTADDFRGMYEVNLVAMFTLCQQAARVLPEGGRIVNLASRAAFGARNYAHYVASKAAVAGLTK ALALELAGRQITVNAVAPGVIATDMLLERSEGLEGLRVQQPTGKLGTPEHIAHAVAFFADPRAEYVTGQVLIVDGGRSVG GTAAF >Mature_244_residues TSQPLTTAIVTGAGSGIGRAIAHRLADEGHAVVVADRAAEGAQETVRQLVAMGRSARAAVLDITDPAATQALIDGAENLR VLVNNAGIFNTCAFDALTADDFRGMYEVNLVAMFTLCQQAARVLPEGGRIVNLASRAAFGARNYAHYVASKAAVAGLTKA LALELAGRQITVNAVAPGVIATDMLLERSEGLEGLRVQQPTGKLGTPEHIAHAVAFFADPRAEYVTGQVLIVDGGRSVGG TAAF
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=33.1983805668016, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=37.1428571428571, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI40254992, Length=233, Percent_Identity=34.3347639484979, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=34.5679012345679, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=34.5528455284553, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI7705925, Length=234, Percent_Identity=32.9059829059829, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=31.6793893129771, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI66933014, Length=228, Percent_Identity=29.8245614035088, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=30.8333333333333, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI4758504, Length=250, Percent_Identity=31.2, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=30.1724137931034, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI225579078, Length=215, Percent_Identity=32.093023255814, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI166795268, Length=207, Percent_Identity=29.951690821256, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI83715985, Length=250, Percent_Identity=29.6, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=32.0855614973262, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI4504505, Length=182, Percent_Identity=29.1208791208791, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI142976729, Length=197, Percent_Identity=27.9187817258883, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=38.4937238493724, Blast_Score=134, Evalue=4e-33, Organism=Escherichia coli, GI1788459, Length=238, Percent_Identity=37.3949579831933, Blast_Score=120, Evalue=7e-29, Organism=Escherichia coli, GI1787905, Length=237, Percent_Identity=38.8185654008439, Blast_Score=117, Evalue=8e-28, Organism=Escherichia coli, GI87082160, Length=242, Percent_Identity=34.7107438016529, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=35.2, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=31.6666666666667, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=35.0806451612903, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=31.3807531380753, Blast_Score=103, Evalue=9e-24, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=30.7392996108949, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=33.7552742616034, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=30.327868852459, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=28.7937743190661, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=30.0884955752212, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=38.75, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=32.8301886792453, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=32.8, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17561402, Length=247, Percent_Identity=35.6275303643725, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=31.640625, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=34.3629343629344, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=31.9230769230769, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=32.3651452282158, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=32.183908045977, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=31.6981132075472, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=30.5343511450382, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=31.25, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=33.4630350194552, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=28.6274509803922, Blast_Score=94, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.4393939393939, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=30.078125, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=28.2352941176471, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=32.9457364341085, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17536651, Length=244, Percent_Identity=28.2786885245902, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=30.46875, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=30.46875, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17536025, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI115534694, Length=237, Percent_Identity=30.8016877637131, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=30.078125, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=237, Percent_Identity=27.8481012658228, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=27.8481012658228, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=24.8062015503876, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=26.0683760683761, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17567345, Length=196, Percent_Identity=29.0816326530612, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17568967, Length=187, Percent_Identity=31.5508021390374, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=31.0526315789474, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=28.4552845528455, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=258, Percent_Identity=28.6821705426357, Blast_Score=73, Evalue=5e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=166, Percent_Identity=31.9277108433735, Blast_Score=69, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=30.0492610837438, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322067, Length=231, Percent_Identity=29.8701298701299, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=36.9294605809129, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=35.8267716535433, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=33.7552742616034, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=32.5, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI23397609, Length=241, Percent_Identity=34.0248962655602, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=33.739837398374, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=31.9672131147541, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644337, Length=224, Percent_Identity=32.5892857142857, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=30.5418719211823, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=226, Percent_Identity=25.2212389380531, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25334; Mature: 25203
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSQPLTTAIVTGAGSGIGRAIAHRLADEGHAVVVADRAAEGAQETVRQLVAMGRSARAA CCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEE VLDITDPAATQALIDGAENLRVLVNNAGIFNTCAFDALTADDFRGMYEVNLVAMFTLCQQ EEECCCCHHHHHHHCCCCCEEEEEECCCEEHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH AARVLPEGGRIVNLASRAAFGARNYAHYVASKAAVAGLTKALALELAGRQITVNAVAPGV HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH IATDMLLERSEGLEGLRVQQPTGKLGTPEHIAHAVAFFADPRAEYVTGQVLIVDGGRSVG HHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHEECEEEEEECCCCCC GTAAF CCCCC >Mature Secondary Structure TSQPLTTAIVTGAGSGIGRAIAHRLADEGHAVVVADRAAEGAQETVRQLVAMGRSARAA CCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEE VLDITDPAATQALIDGAENLRVLVNNAGIFNTCAFDALTADDFRGMYEVNLVAMFTLCQQ EEECCCCHHHHHHHCCCCCEEEEEECCCEEHHHHHHHCCHHHHCCCHHHHHHHHHHHHHH AARVLPEGGRIVNLASRAAFGARNYAHYVASKAAVAGLTKALALELAGRQITVNAVAPGV HHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCH IATDMLLERSEGLEGLRVQQPTGKLGTPEHIAHAVAFFADPRAEYVTGQVLIVDGGRSVG HHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCHHHEECEEEEEECCCCCC GTAAF CCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]