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The map label for this gene is siaP [H]

Identifier: 119386208

GI number: 119386208

Start: 643024

End: 644049

Strand: Direct

Name: siaP [H]

Synonym: Pden_3497

Alternate gene names: 119386208

Gene position: 643024-644049 (Clockwise)

Preceding gene: 119386207

Following gene: 119386209

Centisome position: 37.17

GC content: 67.74

Gene sequence:

>1026_bases
ATGAAAACCCTGATCCTGTCGGCCATCGCCTCGCTTTCGCTGGGCGGCGCGGCCTTTGCCGCCGATGTGACGCTGCGCGT
CCATCACTTCCTGTCGGCCGATGCGCCGCTGCAAACCGAGATCCTGATCCCCTGGGAAAAGGCCGTCGAGGAACAGTCGG
GCGGCCGCATCGACGTGCAACTGTTTCCCTCGATGCAATTGGGAGGCAAGCCGCCGCAGCTGTTCGACCAGGCCCGCGAC
GGCATCGTGGACATTTCCTGGACGCTGCTGGGCTACACGCCCGGCCGCTTCCCCGTGGCCGAGGTGTTCGAGCTGCCCTT
CATGTCCGGCACCGCCGTCCAGACCACCGCCGCGCTGCAAGACTTCCAGGCGAAATACCTGGGCGACGAGATGGGGCAGG
TGAAGCCGCTCTTGCTGCATGCCCCGGCGGGCTACAAGTTCCACATGCGCAGCGGCCCGATCACCTCGCTGGCCGACCTC
AAGGGCAAGAAGATCCGCGCCCCCTCGCGCGCGATGACCGATGCGCTGAACGCGCTGGGCGCCACTGCGGTGGGCATGCC
GGTGCCCGAGGTCGCTCAGGCCCTGACCACCGGCGTGATCGACGGCGCCCAGATCCCGTGGGAGGTCGTGGGCTCGCTGC
GGGTCAACGAGATCACCAACGCCCATAGCGAAATCGGGGTCGAGAACGGCGGCGTTTCCACCGCGGTCATGGCGCTGGTG
ATGAACCGGGCGAAATACGACAGCCTGCCCGACGACCTGAAAAAGGTGATCGACGACAATTCCGGTGCCAACCTGGCGGT
GCTGGCCGGCGAGGCCCTGGACCGGGTCGAGGCCGAGGAACGGCAGAAAGCCCTGGACGCTGGCGCGCAGATCAACGTGA
TCCCGGCCGAGCAGATGGAGGAATGGCGCAGCGCGGTGCAGCCGGTGGTGGACGGTTGGGTCAAGGCCATGGACGGCCGC
GGCCTGGACGGACAGGCGATGCTGGACGACGCGCGCGCCATGCTGGCCGCGGCCGGCGCCGAGTAA

Upstream 100 bases:

>100_bases
GGACTGGGCCGAGGCGCTGCGGCCCGAAAACCTGACCGGCGCCGCGCCAGACCAGGCGCGCGCCGCACGACCGATCTGAA
CAACGCAACGGGAGGAAACC

Downstream 100 bases:

>100_bases
GGGGAGGCGAGGGCGACATGACCGAAGCCGAACCCCTGACCGAACAGCCCCATCCGGTGCCGGTGCCCGGCTGGCTGGTC
GCCCTCTGCCGCTGGTTTGC

Product: TRAP dicarboxylate transporter- DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKTLILSAIASLSLGGAAFAADVTLRVHHFLSADAPLQTEILIPWEKAVEEQSGGRIDVQLFPSMQLGGKPPQLFDQARD
GIVDISWTLLGYTPGRFPVAEVFELPFMSGTAVQTTAALQDFQAKYLGDEMGQVKPLLLHAPAGYKFHMRSGPITSLADL
KGKKIRAPSRAMTDALNALGATAVGMPVPEVAQALTTGVIDGAQIPWEVVGSLRVNEITNAHSEIGVENGGVSTAVMALV
MNRAKYDSLPDDLKKVIDDNSGANLAVLAGEALDRVEAEERQKALDAGAQINVIPAEQMEEWRSAVQPVVDGWVKAMDGR
GLDGQAMLDDARAMLAAAGAE

Sequences:

>Translated_341_residues
MKTLILSAIASLSLGGAAFAADVTLRVHHFLSADAPLQTEILIPWEKAVEEQSGGRIDVQLFPSMQLGGKPPQLFDQARD
GIVDISWTLLGYTPGRFPVAEVFELPFMSGTAVQTTAALQDFQAKYLGDEMGQVKPLLLHAPAGYKFHMRSGPITSLADL
KGKKIRAPSRAMTDALNALGATAVGMPVPEVAQALTTGVIDGAQIPWEVVGSLRVNEITNAHSEIGVENGGVSTAVMALV
MNRAKYDSLPDDLKKVIDDNSGANLAVLAGEALDRVEAEERQKALDAGAQINVIPAEQMEEWRSAVQPVVDGWVKAMDGR
GLDGQAMLDDARAMLAAAGAE
>Mature_341_residues
MKTLILSAIASLSLGGAAFAADVTLRVHHFLSADAPLQTEILIPWEKAVEEQSGGRIDVQLFPSMQLGGKPPQLFDQARD
GIVDISWTLLGYTPGRFPVAEVFELPFMSGTAVQTTAALQDFQAKYLGDEMGQVKPLLLHAPAGYKFHMRSGPITSLADL
KGKKIRAPSRAMTDALNALGATAVGMPVPEVAQALTTGVIDGAQIPWEVVGSLRVNEITNAHSEIGVENGGVSTAVMALV
MNRAKYDSLPDDLKKVIDDNSGANLAVLAGEALDRVEAEERQKALDAGAQINVIPAEQMEEWRSAVQPVVDGWVKAMDGR
GLDGQAMLDDARAMLAAAGAE

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=245, Percent_Identity=26.1224489795918, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36163; Mature: 36163

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLILSAIASLSLGGAAFAADVTLRVHHFLSADAPLQTEILIPWEKAVEEQSGGRIDVQ
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCEEEEE
LFPSMQLGGKPPQLFDQARDGIVDISWTLLGYTPGRFPVAEVFELPFMSGTAVQTTAALQ
ECCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHH
DFQAKYLGDEMGQVKPLLLHAPAGYKFHMRSGPITSLADLKGKKIRAPSRAMTDALNALG
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHHHC
ATAVGMPVPEVAQALTTGVIDGAQIPWEVVGSLRVNEITNAHSEIGVENGGVSTAVMALV
CHHCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
MNRAKYDSLPDDLKKVIDDNSGANLAVLAGEALDRVEAEERQKALDAGAQINVIPAEQME
HHHHHCCCCHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEECHHHHH
EWRSAVQPVVDGWVKAMDGRGLDGQAMLDDARAMLAAAGAE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKTLILSAIASLSLGGAAFAADVTLRVHHFLSADAPLQTEILIPWEKAVEEQSGGRIDVQ
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHCCCCEEEEE
LFPSMQLGGKPPQLFDQARDGIVDISWTLLGYTPGRFPVAEVFELPFMSGTAVQTTAALQ
ECCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHCCCCCCCHHHHHHHHH
DFQAKYLGDEMGQVKPLLLHAPAGYKFHMRSGPITSLADLKGKKIRAPSRAMTDALNALG
HHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHHHC
ATAVGMPVPEVAQALTTGVIDGAQIPWEVVGSLRVNEITNAHSEIGVENGGVSTAVMALV
CHHCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHH
MNRAKYDSLPDDLKKVIDDNSGANLAVLAGEALDRVEAEERQKALDAGAQINVIPAEQME
HHHHHCCCCHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCEEEEECHHHHH
EWRSAVQPVVDGWVKAMDGRGLDGQAMLDDARAMLAAAGAE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA